BDNF腦源性神經營養因子重組蛋白 | 貨號4004 (ab285446)
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BDNF腦源性神經營養因子重組蛋白 | 貨號4004 (ab285446)
A potent neurotrophic factor supporting the growth and survival of nerve/glial cells
產品描述：人腦源性神經營養因子/血清腦源性神經營養因素（Human Brain-Derived Neurotrophic Factor , BDGF）是一種有效的神經營養因子 (neurotrophic factor)，可支持神經 (nerve) 和神經膠質細胞 (nerve and glial cells) 的生長和存活。 BDNF的活性形式是27.0kDa二聚體，由兩個相同的119個氨基酸亞基通過強疏水相互作用結合在一起形成。
| Alternate Name | Brain-derived neurotrophic factor, Short name=BDNF, Abrineurin |
| Gene Symbol | BDNF |
| Gene ID | 627 |
| Accession # | P23560 |
| Source | E. coli |
| Appearance | Lyophilized protein |
| Physical Form Description | Sterile filtered and lyophilized with no additives |
| Molecular Weight | 27.0 kDa |
| Purity by SDS-PAGE | ≥98% |
| Purity by | ≥98% |
| Endotoxin Level | <0.1 ng/μg |
| Biological Activity | The ED₅₀ determined by its ability to stimulate chick E8 neurite outgrowth was found to be 0.1-1.0 ng/ml. |
| Reconstitution Instructions | Reconstitute in H₂O to a concentration of 0.1-1.0 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use. |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
引用文獻
Kobayashi et al., Phosphorylation of Cyclin-dependent Kinase 5 (Cdk5) at Tyr-15 Is Inhibited by Cdk5 Activators and Does Not Contribute to the Activation of Cdk5. J. Biol. Chem., Jul 2014; 289: 19627 – 19636.
