Hygromycin B | An antibiotic and a selection agent貨號2589 (ab286934)
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Hygromycin B | 貨號2589 (ab286934)
An antibiotic and a selection agent
產品描述：Hygromycin B是由吸水鏈黴菌（Streptomyces hygroscopicus）產生的氨基糖苷類抗生素，其通常用作含有hph或hygHygromycin B抗性基因的細胞選擇劑。 Hygromycin B被認為通過加強核醣體受體（“A”）位點中肽基-tRNA的相互作用來抑制蛋白質合成，從而防止EF-2（延伸因子-2）的易位。Hygromycin B對大多數細菌，真菌和高等真核生物都有效。
| Alternate Name | (3’R,3aS,4S,4’R,5’R,6R,6’R,7S,7aS)-4-[(1R,2S,3R,5S,6R)-3-amino-2,6-dihydroxy-5-(methylamino)cyclohexyl]oxy-6′-[(1S)-1-amino-2-hydroxyethyl]-6-(hydroxymethyl)spiro[4,6,7,7a-tetrahydro-3aH-[1,3]dioxolo[4,5-c]pyran-2,2′-oxane]-3′,4′,5′,7-tetrol |
| Appearance | Off-white to light tan powder |
| CAS # | 31282-04-9 |
| Molecular Formula | C₂₀H₃₇N₃O₃ |
| Molecular Weight | 527.52 |
| Purity | ≥90% by HPLC |
| Solubility | H₂O (~ 50 mg/ml) |
| InChi Key | GRRNUXAQVGOGFE-KPBUCVLVSA-N |
| PubChem CID | 35766 |
| MDL Number | MFCD06795479 |
| Handling | Protect from light and moisture |
| Storage Conditions | 2-8ºC |
