IPTG ( Isopropyl β-D-thiogalactoside) | MCE (MedChem Express)貨號HY-15921
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MCE inhibitors台灣代理經銷-MCE (MedChem Express) -IPTG ( Isopropyl β-D-thiogalactoside)
MCE總部位於美國新澤西，提供種類齊全的化學及生化研究用產品，包括創新的生命科學試劑，reference compounds(標準化合物)，APIs(原料藥)及Natural compounds(天然化合物)以提供實驗室或科學研究之用，MedChemExpress(MCE)產品50000+ 特異性抑制劑、化合物庫、重組蛋白，專注於信號通路和疾病研究領域。全球文獻廣泛引用，質控體系嚴格，品質100%。
IPTG (Synonyms: Isopropyl β-D-thiogalactoside)
IPTG, Allosteric lac repressor protein inhibitor | MCE貨號HY-15921
IPTG (Isopropyl β-D-thiogalactoside)是異乳糖(allolactose)的分子模擬物，異乳糖(allolactose)是一種乳糖代謝物(lactose metabolite)，可觸發 lac 操縱子的轉錄，因此可用於誘導基因在 lac 操縱子控制下的蛋白質表達。變構 lac 抑制蛋白抑制。IPTG (Isopropyl β-D-thiogalactoside)經常被用來作為乳糖操縱子的誘導物。誘導 β-半乳糖苷酶 (LacZ) 表達。與 X-gal 結合使用，用於重組細菌的藍/白篩選。
IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator.
H2O : 100 mg/mL (419.64 mM; Need ultrasonic)
DMSO : ≥ 60 mg/mL (251.78 mM)
“Cell viability and specific cell death were measured by flow cytometry.Cell viability and specific cell death were measured by flow cytometry.. The following small-molecule inhibitors were used: venetoclax/ABT-199, Q-VD-OPh, IPTG (MedChemExpress, Princeton, NJ, USA), silmitasertib/CX-4945, S63845, MK2206 (Selleckchem, Houston, TX, USA), cycloheximide, puromycin (Sigma-Aldrich, St. Louis, MO, USA), and blasticidin (Thermo Fisher Scientific, Waltham, MA, USA).
| Description |
IPTG is a molecular mimic of allolactose, a lactose metabolite that triggers transcription of the lac operon, and it is therefore used to induce protein expression where the gene is under the control of the lac operator. |
|---|---|
| In Vitro |
IPTG uptake by E. coli can be independent of the action of lactose permease, since other transport pathways are also involved. At low concentration, IPTG enters cells through lactose permease, but at high concentrations (typically used for protein induction), IPTG can enter the cells independently of lactose permease[1]. MCE has not independently confirmed the accuracy of these methods. They are for reference only. |
| Molecular Weight |
238.30 |
| Appearance |
Solid |
| Formula |
C9H18O5S |
| CAS No. | |
| SMILES |
O[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1SC(C)C |
| Shipping |
Room temperature in continental US; may vary elsewhere. |
MCE台灣代理商-BRAND/AGENCY/代理品牌/ MedChemexpress（MCE）台灣代理商
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