BRCA2 抗體 | tumor suppressor貨號3675
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BRCA2 抗體 | tumor suppressor貨號3675
產品介紹: BRCA 1和2是乳腺癌易感性蛋白(breast cancer susceptibility proteins),在DNA損傷(DNA damage),修復(repair),細胞週期進程(cell cycle progression),轉錄(transcription)和細胞凋亡(apoptosis)等過程中發揮作用。BRCA1基因在許多組織(包括乳房和卵巢)中表達,編碼的預測蛋白為1863氨基酸。已顯示BRCA2是Rad51 localization DSBs(雙鏈斷裂, double stranded breaks)位點所必需的。缺少BRCA1和BRCA2的細胞無法通過Rad51依賴性過程修復DSB(雙鏈斷裂 double stranded breaks)。
Antibody Target | BRCA2 |
Host | Rabbit |
Antibody Type | Polyclonal |
Isotype | Rabbit IgG |
Immunogen | Synthetic peptide mapping to the N-terminus of human BRCA2 |
Accession # | P51587 |
Gene ID | 675 |
Appearance | Colorless liquid |
Concentration | 0.5 mg/ml |
Formulation | 0.5 mg/ml in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% proclin |
Purification | Affinity purified |
Species Reactivity | Human, mouse |
Application | Western blot |
Application & Usage | Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. HeLa cell lysate can be used as a positive control. |
Handling | The antibody solution should be gently mixed before use. |
Storage Conditions | -20 °C |
Shipping Conditions | Gel Pack |
Olaparib (PARP抑制劑) | Rucapar (PARP抑制劑) | Tosylate | Talazoparib | PARP1 (Human) ELISA Kit |BRCA1 抗體 |BRCA2 抗體