PARP1 (Human) ELISA Kit 貨號K4218

PARP1 (Human) ELISA Kit

鹼基切除修復（base excision repair pathway , BER）途徑，通過催化參與染色質結構(chromatin architecture)和DNA代謝(DNA metabolism)的有限數量受體蛋白(acceptor proteins) 的聚（ADP-核糖基）化。 這種修飾是在DNA損傷後進行的，並作為檢測(detection )/信號通路(signaling pathway)中必不可少的步驟，導致DNA鏈斷裂的修復。Mediates APLF和CHFR的聚（ADP-核糖基）化。正調節MTUS1的轉錄(transcription)，負調節MTUS2 / TIP150的轉錄(transcription)。與EEF1A1和TXK形成複合物(complex)，該複合物充當T輔助1（Th1）細胞特異性轉錄因子(cell-specific transcription factor)，並與IFN-γ的啟動子結合，直接調節其轉錄，因此重要地參與了Th1細胞因子的產生。 BioVision的PARP1 ELISA試劑盒是一種夾心ELISA測定法 ( sandwich ELISA assay)，用於定量測量血清(serum)，血漿(plasma)和細胞培養上清液中(culture supernatants) 的人PARP1。顏色的密度與從樣品中捕獲的PARP1的數量成正比。此產品需由儀器進行定量 ELISA儀器設備請按此。

Cat # +Size	K4218-100
Size	100 assays
Detection Method	Absorbance (450 nm)
Species Reactivity	Human
Applications	This ELISA kit is used for quantitative measurement of PARP-1 in human serum, plasma, tissue homogenates and other biological fluids.
Features & Benefits	• Easy, convenient and time-saving method to measure the level of PARP-1 in serum, plasma, tissue homogenates, culture supernatants and other biological fluids. Detection Range: 0.625 – 40 ng/ml Sensitivity: < 0.375 ng/ml • Cross Reactivity: No significant cross-reactivity or interference between this analyte and its analogues was observed.
Kit Components	• Microplate: 96 wells • Lyophilized Standard • Sample / Standard dilution buffer • Biotin- detection antibody (Concentrated) • Antibody dilution buffer • HRP-Streptavidin Conjugate (SABC) • SABC dilution buffer • TMB substrate • Stop Solution • Wash buffer (25X) • Plate sealers
Storage Conditions	4°C
Shipping Conditions	Gel Pack

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