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Azithromycin | CAS#83905-01-5貨號B1226-100

A macrolide antibiotic

產品描述:  阿奇黴素 (Azithromycin) 是一種屬於大環內酯(macrolide antibiotic)的抗生素。阿奇黴素可抑制革蘭氏陽性(gram positive)和陰性細菌(negative bacteria)在轉肽(transpeptidation)步驟中50S核醣體亞基的形成和延長。與小鼠模型中的紅黴素(erythromycin)相比，體內活性顯示出改善的藥代動力學特性(pharmacokinetic properties)。

Alternate Name	13-[(2,6-Dideoxy-3-C-methyl-3-O-methyl-α-L-ribo-hexopyranosyl)oxy]-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-[[3,4,6-trideoxy-3-(dimethylamino)-β-D-xylo-hexopyranosyl]oxy]-1-oxa-6-azacyclopentadecan-15-one
Appearance	White solid
CAS #	83905-01-5
Molecular Formula	C₃₈H₇₂N₂O₁₂
Molecular Weight	748.98
Purity	≥98% by HPLC
Solubility	DMSO (>50 mg/ml)
SMILES	CCC1C(C(C(N(CC(CC(C(C(C(C(C(=O)O1)C)OC2CC(C(C(O2)C)O)(C)OC)C)OC3C(C(CC(O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O
InChi	CC[C@@H]1[C@@]([C@@H]([C@H](N(C[C@@H](C[C@@]([C@@H]([C@H]([C@@H]([C@H](C(=O)O1)C)O[C@H]2C[C@@]([C@H]([C@@H](O2)C)O)(C)OC)C)O[C@H]3[C@@H]([C@H](C[C@H](O3)C)N(C)C)O)(C)O)C)C)C)O)(C)O
InChi Key	MQTOSJVFKKJCRP-BICOPXKESA-N
PubChem CID	447043

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