Recombinant Human EGF表皮生長因子重組蛋白 |貨號Z100139 (1MG)
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特點
【Growth factors&cytokines細胞生長因子】 CHO cell/HEK293 /E.coli表現系統
生長因子(Growth factors)和細胞因子(cytokines)，是天然存在的信號分子(signaling molecules)，它們是高等生物細胞之間攜帶調節信號的關鍵因素。儘管細胞因子主要與免疫系統(immune system housekeeping)相關，生長因子(Growth factors)在生物體的發育和成熟階段調節具廣泛的過程；不受控制的生長因子激活通常與腫瘤(oncogenesis)發生相關。生長因子(Growth factors)和細胞因子對於細胞的許多功能是不可缺少的。傳統的細胞生物學實驗使用動物血清作為正常細胞代謝所需的生長因子和營養來源。但是，使用動物血清，容易增加病毒，支原體和朊病毒污染的風險；與血清收集相關的高成本和倫理問題；對可能還含有生長抑制劑。高品質Growth factors&cytokines產品具有以下特點：(A) 嚴格條件下的高純度生產確保質量保持一致，每批批次純度≥95％通過SDS-PAGE. (B) 內毒素最小 – Limulus Amebocyte Lysate (LAL) assay。低於1 EU/ug recombinant protein。(C) 確保每一批生物活性。
Recombinant Human EGF表皮生長因子重組蛋白 |貨號Z100139 (1MG)
產品介紹: 表皮生長因子 (Epidermal growth factor , EGF) 是一種小的促有絲分裂蛋白( small mitogenic protein )，被認為參與正常細胞生長( normal cell growth)、腫瘤發生(oncogenesis)和傷口癒合(wound healing)等機制。該蛋白與人類 α 型轉化生長因子 (human type-alpha transforming growth factor, hTGF α) 表現出強烈的序列和功能同源性，hTGF α 是 EGF 受體位點(EGF receptor sites)的競爭者。 EGF受體(EGF receptors)幾乎在所有類型的組織中表現。壁內胚層(Parietal endoderm)、成熟骨骼肌(mature skeletal muscles)和造血組織( hematopoietic tissues)不表達此受體。 EGF 受體(EGF receptor)，稱為 HER1，是一種 170 kDa 跨膜糖蛋白(transmembrane glycoprotein)，長度為 1186 個胺基酸(1186 amino acids)。它與先前描述的稱為 SA-7（species antigen 7) 物種抗原 7的糖蛋白相同。胞外受體結構域(extracellular receptor domain)長度為621個胺基酸，包括11個糖基化天門冬胺酸殘基(glycosylated asparagine residues)和51個半胱胺酸殘基(cysteine residues)。此結構域包含 EGF 結合位點，也結合哺乳動物 TGF-α。
| Cat. No. | Z100139 |
| Name | Recombinant Human EGF |
| Description | Epidermal growth factor (EGF) is a small mitogenic protein that is thought to be involved in mechanisms such as normal cell growth, oncogenesis, and wound healing. This protein shows both strong sequential and functional homology with human type-alpha transforming growth factor (hTGF alpha), which is a competitor for EGF receptor sites. EGF receptors are expressed in almost all types of tissues. Parietal endoderm, mature skeletal muscles, and hematopoietic tissues do not express the receptor. The EGF receptor, designated HER1, is a 170 kDa transmembrane glycoprotein with a length of 1186 amino acids. It is identical with a previously described glycoprotein called SA-7 (species antigen 7). The extracellular receptor domain has a length of 621 amino acids, including 11 glycosylated asparagine residues and 51 cysteine residues. This domain contains the EGF binding site and also binds mammalian TGF-alpha. |
| Organism | Human (H. sapiens) |
| Unit quantity | 1.0 mg |
| Family | EGF Family |
| Aliases | BRCACOX, BRCOX |
| Gene Symbol | Acox2 |
| Gene ID | 1258 |
| Accession Number | NM_053115 |
| Source | E. coli |
| Species | Human (H. sapiens) |
| Appearance | Lyophilized Powder |
| Molecular Weight | 6.5 kDa |
| Endotoxin Level | <1.0 EU/µg of recombinant protein as determined by the LAL method. |
| Purity | >95% as determined by SDS-PAGE |
| Formulation | Recombinant Epidermal Growth Factor was lyophilized from a 0.2 μm filtered solution in PBS. |
| Function | The ED(50) was determined by the dose-dependent proliferation of HeLa cells and was found to be <2ng/mL. |
| Reconstitution | A quick spin of the vial followed by reconstitution in sterile distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Storage | The lyophilized protein is stable for at least one year from date of receipt at -70°C. Upon reconstitution, this cytokine can be stored in working aliquots at 2° – 8°C for one month, or at -20°C for six months, with a carrier protein without detectable loss of activity. Avoid repeated freeze/thaw cycles. |
| Usage | For research use only. Not for diagnostic or therapeutic use. |
aFGF重組蛋白 | IL-2重組蛋白 | 幹細胞因子（KITLG） | 重組人白血病抑制因子（LIF） | 重組人Human Noggin (NOG) | TNF-a | BMP2
| ABM重組蛋白貨號 | 重組蛋白品項 | 包裝規格 |
| Z102119 | Recombinant Human VEGF (121aa) | 10 x 100 µg (Z102117 x 10) |
| Z100895 | Recombinant Human VEGF (165aa) | 10 µg |
| Z100897 | Recombinant Human VEGF (165aa) | 100 µg |
| Z100899 | Recombinant Human VEGF (165aa) | 10 x 100 µg (10 x Z100897) |
| Z102535 | Recombinant Human VEGFB | 20 µg |
| Z500405 | Recombinant Human VRK1 (N-GST tag) | 10 µg |
| Z500406 | Recombinant Human VRK2 (N-GST tag) | 10 µg |
| Z101925 | Recombinant Human WISP2 | 20 µg |
| Z102545 | Recombinant Human WISP3 | 5 µg |
| Z500407 | Recombinant Human WNK1 (N-GST tag) | 10 µg |
| Z500408 | Recombinant Human WNK2 (N-GST tag) | 10 µg |
| Z102125 | Recombinant Human WNT1 | 10 µg |
| Z500409 | Recombinant Human YES1 (N-GST tag) | 10 µg |
| Z500410 | Recombinant Human YSK4 (MAP3K19) (N-GST tag) | 10 µg |
| Z500411 | Recombinant Human ZAK (N-GST tag) | 10 µg |
| Z500412 | Recombinant Human ZAP70 (N-GST tag) | 10 µg |
| Z600001 | Recombinant Mouse ABL1 (N-His tag) | 10 µg |
| Z600002 | Recombinant Mouse AURORA A (N-GST tag) | 10 µg |
| Z200265 | Recombinant Mouse Beta-Defensin 1 (DEFB1) | 20 µg |
| Z200269 | Recombinant Mouse Beta-Defensin 1 (DEFB1) | 500 µg |
| Z200285 | Recombinant Mouse Beta-Defensin 2 (DEFB2) | 20 µg |
| Z200289 | Recombinant Mouse Beta-Defensin 2 (DEFB2) | 1.0 mg |
| Z200275 | Recombinant Mouse Beta-Defensin 3 (DEFB3) | 20 µg |
| Z200279 | Recombinant Mouse Beta-Defensin 3 (DEFB3) | 1.0 mg |
| Z600004 | Recombinant Mouse BRSK1 (N-GST tag) | 10 µg |
| Z600007 | Recombinant Mouse CAMK1 (N-GST tag) | 10 µg |
| Z600006 | Recombinant Mouse CAMK1 beta (N-GST tag) | 10 µg |
| Z200315 | Recombinant Mouse CCL22 | 20 µg |
| Z200319 | Recombinant Mouse CCL22 | 1.0 mg |
| Z200325 | Recombinant Mouse CCL25 | 20 µg |
| Z200329 | Recombinant Mouse CCL25 | 1.0 mg |
| Z200345 | Recombinant Mouse CXCL1 | 25 µg |
| Z200347 | Recombinant Mouse CXCL1 | 100 µg |
| Z200349 | Recombinant Mouse CXCL1 | 1.0 mg |
| Z200205 | Recombinant Mouse CXCL12 (SDF-1 beta) | 10 µg |
| Z200209 | Recombinant Mouse CXCL12 (SDF-1 beta) | 1.0 mg |
| Z200355 | Recombinant Mouse CXCL2 | 20 µg |
| Z200357 | Recombinant Mouse CXCL2 | 100 µg |
| Z200359 | Recombinant Mouse CXCL2 | 1.0 mg |
| Z200305 | Recombinant Mouse CXCL4 (PF4) | 20 µg |
| Z200309 | Recombinant Mouse CXCL4 (PF4) | 1.0 mg |
| Z200025 | Recombinant Mouse EGF | 500 µg |
| Z200029 | Recombinant Mouse EGF | 1.0 mg |
| Z200545 | Recombinant Mouse EGFL7 | 25 µg |
| Z200035 | Recombinant Mouse Eotaxin (CCL11) | 20 µg |
| Z200037 | Recombinant Mouse Eotaxin (CCL11) | 100 µg |
| Z200039 | Recombinant Mouse Eotaxin (CCL11) | 1.0 mg |
| Z200405 | Recombinant Mouse Eotaxin-2 (CCL24) | 20 µg |
| Z200409 | Recombinant Mouse Eotaxin-2 (CCL24) | 1.0 mg |
| Z600009 | Recombinant Mouse EPHA1 (N-GST tag) | 10 µg |
| Z600010 | Recombinant Mouse EPHA7 (N-GST tag) | 10 µg |
| Z600011 | Recombinant Mouse EPHB1 (N-GST tag) | 10 µg |
| Z200045 | Recombinant Mouse Exodus-2 (CCL21A) | 20 µg |
| Z200049 | Recombinant Mouse Exodus-2 (CCL21A) | 1.0 mg |
| Z600012 | Recombinant Mouse FER (N-GST tag) | 10 µg |
| Z200005 | Recombinant Mouse FGF1 | 50 µg |
| Z200007 | Recombinant Mouse FGF1 | 200 µg |
| Z200009 | Recombinant Mouse FGF1 | 1.0 mg |
| Z200015 | Recombinant Mouse FGF2 | 50 µg |
| Z200017 | Recombinant Mouse FGF2 | 250 µg |
| Z200019 | Recombinant Mouse FGF2 | 1.0 mg |
| Z200635 | Recombinant Mouse FGF8 | 50 µg |
| Z200639 | Recombinant Mouse FGF8 | 1.0 mg |
| Z200055 | Recombinant Mouse FLT3 Ligand (FLT3LG) | 10 µg |
| Z200059 | Recombinant Mouse FLT3 Ligand (FLT3LG) | 1.0 mg |
| Z200605 | Recombinant Mouse G-CSF (CSF3) | 10 µg |
| Z200065 | Recombinant Mouse GH1 | 50 µg |
| Z200067 | Recombinant Mouse GH1 | 200 µg |
| Z200069 | Recombinant Mouse GH1 | 1.0 mg |
| Z200075 | Recombinant Mouse GM-CSF (CSF2) | 20 µg |
| Z200077 | Recombinant Mouse GM-CSF (CSF2) | 5 x 20 µg (Z200075 x 5) |
| Z200079 | Recombinant Mouse GM-CSF (CSF2) | 1.0 mg |
| Z200415 | Recombinant Mouse GRO gamma (CXCL3) | 20 µg |
| Z200417 | Recombinant Mouse GRO gamma (CXCL3) | 200 µg |
| Z200419 | Recombinant Mouse GRO gamma (CXCL3) | 1.0 mg |
| Z600013 | Recombinant Mouse HIPK2 (N-GST tag) | 10 µg |
| Z200085 | Recombinant Mouse IFNG | 100 µg |
| Z200089 | Recombinant Mouse IFNG | 1.0 mg |
| Z200625 | Recombinant Mouse IGF1 | 20 µg |
| Z200115 | Recombinant Mouse IL10 | 10 µg |
| Z200119 | Recombinant Mouse IL10 | 1.0 mg |
| Z200125 | Recombinant Mouse IL11 | 10 µg |
| Z200127 | Recombinant Mouse IL11 | 100 µg |
| Z200129 | Recombinant Mouse IL11 | 1.0 mg |
| Z200245 | Recombinant Mouse IL13 | 10 µg |
| Z200247 | Recombinant Mouse IL13 | 100 µg |
| Z200249 | Recombinant Mouse IL13 | 1.0 mg |
| Z200435 | Recombinant Mouse IL17 | 25 µg |
| Z200437 | Recombinant Mouse IL17 | 100 µg |
| Z200439 | Recombinant Mouse IL17 | 1.0 mg |
| Z200655 | Recombinant Mouse IL18 | 5 µg |
| Z200657 | Recombinant Mouse IL18 | 25 µg |
| Z200659 | Recombinant Mouse IL18 | 1.0 mg |
| Z200429 | Recombinant Mouse IL18BP | 1.0 mg |
| Z200095 | Recombinant Mouse IL1A | 10 µg |
| Z200097 | Recombinant Mouse IL1A | 100 µg |
| Z200099 | Recombinant Mouse IL1A | 1.0 mg |
| Z200105 | Recombinant Mouse IL1B | 10 µg |
| Z200107 | Recombinant Mouse IL1B | 100 µg |
| Z200109 | Recombinant Mouse IL1B | 1.0 mg |
| Z200135 | Recombinant Mouse IL2 | 20 µg |
| Z200137 | Recombinant Mouse IL2 | 100 µg |
| Z200139 | Recombinant Mouse IL2 | 1.0 mg |
| Z200255 | Recombinant Mouse IL25 | 10 µg |
| Z200257 | Recombinant Mouse IL25 | 100 µg |
| Z200259 | Recombinant Mouse IL25 | 1.0 mg |
| Z200145 | Recombinant Mouse IL3 | 10 µg |
| Z200149 | Recombinant Mouse IL3 | 1.0 mg |
| Z200155 | Recombinant Mouse IL33 | 10 µg |
| Z200157 | Recombinant Mouse IL33 | 100 µg |
| Z200159 | Recombinant Mouse IL33 | 1.0 mg |
| Z200165 | Recombinant Mouse IL4 | 10 µg |
| Z200169 | Recombinant Mouse IL4 | 1.0 mg |
| Z200475 | Recombinant Mouse IL5 | 25 µg |
| Z200175 | Recombinant Mouse IL6 | 10 µg |
| Z200177 | Recombinant Mouse IL6 | 100 µg |
| Z200179 | Recombinant Mouse IL6 | 1.0 mg |
| Z200645 | Recombinant Mouse IL7 | 10 µg |
| Z600014 | Recombinant Mouse JNK1 (N-GST tag) | 10 µg |
| Z200185 | Recombinant Mouse KGF (FGF7) | 10 µg |
| Z200187 | Recombinant Mouse KGF (FGF7) | 100 µg |
| Z200189 | Recombinant Mouse KGF (FGF7) | 1.0 mg |
| Z200195 | Recombinant Mouse LIF | 10 µg |
| Z200197 | Recombinant Mouse LIF | 100 µg |
| Z200199 | Recombinant Mouse LIF | 1.0 mg |
| Z200485 | Recombinant Mouse LIF | 100 µg |
| Z200555 | Recombinant Mouse LIX (CXCL5) | 20 µg |
| Z200557 | Recombinant Mouse LIX (CXCL5) | 200 µg |
| Z200559 | Recombinant Mouse LIX (CXCL5) | 1.0 mg |
| Z200395 | Recombinant Mouse MCP-2 (CCL8) | 20µg |
| Z200397 | Recombinant Mouse MCP-2 (CCL8) | 200 µg |
| Z200399 | Recombinant Mouse MCP-2 (CCL8) | 1.0 mg |
| Z200385 | Recombinant Mouse MCP-5 (CCL12) | 25 µg |
| Z200387 | Recombinant Mouse MCP-5 (CCL12) | 100 µg |
| Z200389 | Recombinant Mouse MCP-5 (CCL12) | 1.0 mg |
| Z200335 | Recombinant Mouse MEC (CCL28) | 20 µg |
| Z200339 | Recombinant Mouse MEC (CCL28) | 1.0 mg |
| Z600015 | Recombinant Mouse MEK1 (EE) (N-GST tag) | 10 µg |
| Z200295 | Recombinant Mouse MIF | 25 µg |
| Z200297 | Recombinant Mouse MIF | 100 µg |
| Z200299 | Recombinant Mouse MIF | 1.0 mg |
| Z200375 | Recombinant Mouse MIP-1 gamma (CCL9) | 20 µg |
| Z200379 | Recombinant Mouse MIP-1 gamma (CCL9) | 1.0 mg |
| Z200455 | Recombinant Mouse MIP-3 (CCL19) | 20 µg |
| Z200459 | Recombinant Mouse MIP-3 (CCL19) | 1.0 mg |
| Z600017 | Recombinant Mouse MSK2 (N-GST tag) | 10 µg |
| Z600018 | Recombinant Mouse NEK1 (N-GST tag) | 10 µg |
| Z200235 | Recombinant Mouse Noggin (NOG) | 20 µg |
| Z600019 | Recombinant Mouse PAK3 (N-GST tag) | 10 µg |
| Z600020 | Recombinant Mouse PDGFR alpha (N-GST tag) | 10 µg |
| Z600021 | Recombinant Mouse PIM3 (N-GST tag) | 10 µg |
| Z200495 | Recombinant Mouse Prolactin (PRL) | 10 µg |
| Z200615 | Recombinant Mouse SHH | 25 µg |
| Z200617 | Recombinant Mouse SHH | 250 µg |
| Z200619 | Recombinant Mouse SHH | 1.0 mg |
| Z200365 | Recombinant Mouse SR-PSOX (CXCL16) | 25 µg |
| Z200369 | Recombinant Mouse SR-PSOX (CXCL16) | 1.0 mg |
| Z200595 | Recombinant Mouse Stem Cell Factor (KITLG) | 10 µg |
| Z200597 | Recombinant Mouse Stem Cell Factor (KITLG) | 10 x 10 µg |
| Z200505 | Recombinant Mouse Stem Cell Factor (KITLG) | 100 µg |
| Z200599 | Recombinant Mouse Stem Cell Factor (KITLG) | 1.0 mg |
| Z600025 | Recombinant Mouse TGFBR1 (ALK5) (N-GST tag) | 10 µg |
| Z600026 | Recombinant Mouse TGFBR2 (N-GST tag) | 10 µg |
| Z200535 | Recombinant Mouse THPO | 10 µg |
| Z200539 | Recombinant Mouse THPO | 1.0 mg |
| Z200215 | Recombinant Mouse TNF | 50 µg |
| Z200217 | Recombinant Mouse TNF | 100 µg |
| Z200219 | Recombinant Mouse TNF | 1.0 mg |
| Z600027 | Recombinant Mouse TTBK2 (N-GST tag) | 10 µg |
| Z200585 | Recombinant Mouse VEGF (120aa) | 10 µg |
| Z200587 | Recombinant Mouse VEGF (120aa) | 100 µg |
| Z200589 | Recombinant Mouse VEGF (120aa) | 1.0 mg |
| Z200575 | Recombinant Mouse VEGF (164aa) | 10 µg |
| Z200577 | Recombinant Mouse VEGF (164aa) | 100 µg |
| Z200579 | Recombinant Mouse VEGF (164aa) | 1.0 mg |
| Z600029 | Recombinant Mouse WNK4 (N-GST tag) | 10 µg |
| Z400015 | Recombinant Porcine LIF | 10 µg |
| Z400017 | Recombinant Porcine LIF | 100 µg |
| Z400019 | Recombinant Porcine LIF | 1.0 mg |
| Z600003 | Recombinant Rat BMX (N-GST tag) | 10 µg |
| Z600005 | Recombinant Rat BTK (N-His tag) | 10 µg |
| Z600008 | Recombinant Rat CAMKK1 (N-GST tag) | 10 µg |
| Z300035 | Recombinant Rat CNTF | 20 µg |
| Z300037 | Recombinant Rat CNTF | 100 µg |
| Z300039 | Recombinant Rat CNTF | 1.0 mg |
| Z300105 | Recombinant Rat CXCL1 | 25 µg |
| Z300107 | Recombinant Rat CXCL1 | 100 µg |
| Z300109 | Recombinant Rat CXCL1 | 1.0 mg |
| Z300115 | Recombinant Rat CXCL2 | 20 µg |
| Z300117 | Recombinant Rat CXCL2 | 100 µg |
| Z300119 | Recombinant Rat CXCL2 | 1.0 mg |
| Z300045 | Recombinant Rat EGF | 100 µg |
| Z300049 | Recombinant Rat EGF | 1.0 mg |
| Z300145 | Recombinant Rat Eotaxin (CCL11) | 20 µg |
| Z300147 | Recombinant Rat Eotaxin (CCL11) | 100 µg |
| Z300149 | Recombinant Rat Eotaxin (CCL11) | 1.0 mg |
| Z300005 | Recombinant Rat FGF2 | 50 µg |
| Z300009 | Recombinant Rat FGF2 | 1.0 mg |
| Z300185 | Recombinant Rat G-CSF (CSF3) | 5 µg |
| Z300187 | Recombinant Rat G-CSF (CSF3) | 100 µg |
| Z300135 | Recombinant Rat GRO gamma (CXCL3) | 10 µg |
| Z300137 | Recombinant Rat GRO gamma (CXCL3) | 100 µg |
| Z300139 | Recombinant Rat GRO gamma (CXCL3) | 1.0 mg |
| Z300015 | Recombinant Rat IFNG | 100 µg |
| Z300019 | Recombinant Rat IFNG | 1.0 mg |
| Z300055 | Recombinant Rat IGF1 | 50 µg |
| Z300057 | Recombinant Rat IGF1 | 250 µg |
| Z300059 | Recombinant Rat IGF1 | 1.0 mg |
| Z300025 | Recombinant Rat IL10 | 20 µg |
| Z300029 | Recombinant Rat IL10 | 1.0 mg |
| Z300095 | Recombinant Rat IL13 | 10 µg |
| Z300099 | Recombinant Rat IL13 | 1.0 mg |
| Z300175 | Recombinant Rat IL17 | 25 µg |
| Z300179 | Recombinant Rat IL17 | 1.0 mg |
| Z300075 | Recombinant Rat IL1B | 10 µg |
| Z300077 | Recombinant Rat IL1B | 100 µg |
| Z300079 | Recombinant Rat IL1B | 1.0 mg |
| Z300195 | Recombinant Rat IL2 | 5 µg |
| Z300197 | Recombinant Rat IL2 | 100 µg |
| Z300199 | Recombinant Rat IL2 | 1.0 mg |
| Z300165 | Recombinant Rat IL20 | 10 µg |
| Z300169 | Recombinant Rat IL20 | 1.0 mg |
| Z300205 | Recombinant Rat IL3 | 5 µg |
| Z300155 | Recombinant Rat IL5 | 10 µg |
| Z300159 | Recombinant Rat IL5 | 1.0 mg |
| Z300085 | Recombinant Rat IL6 | 10 µg |
| Z300089 | Recombinant Rat IL6 | 1.0 mg |
| Z300125 | Recombinant Rat LIX (CXCL5) | 20 µg |
| Z300129 | Recombinant Rat LIX (CXCL5) | 1.0 mg |
| Z600016 | Recombinant Rat MET (N-GST tag) | 10 µg |
| Z600024 | Recombinant Rat TEC (N-GST tag) | 10 µg |
| Z300065 | Recombinant Rat TNF | 20 µg |
| Z300067 | Recombinant Rat TNF | 100 µg |
| Z300069 | Recombinant Rat TNF | 1.0 mg |
| Z600028 | Recombinant Rat TXK (N-GST tag) | 10 µg |
| Z600023 | Recombinant Rous Sarcoma Virus SRC (N-GST tag) | 10 µg |
| Z600022 | Recombinant Xenopus PKC alpha (N-GST tag) | 10 µg |