重組人白血病抑制因子（LIF） | Leukemia Inhibitory Factor ABM貨號Z101345
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【Growth factors&cytokines細胞生長因子】 CHO cell/HEK293 /E.coli表現系統
Growth factors生長因子和cytokines細胞因子，是天然存在的signaling molecules信號分子，它們是高等生物細胞之間攜帶調節信號的關鍵因素。儘管細胞因子主要與immune system housekeeping免疫系統相關，生長因子在生物體的發育和成熟階段調節具廣泛的過程；不受控制的生長因子激活通常與oncogenesis腫瘤發生相關。生長因子和細胞因子對於細胞的許多功能是不可缺少的。傳統的細胞生物學實驗使用動物血清作為正常細胞代謝所需的生長因子和營養來源。但是，使用動物血清，容易增加病毒，支原體和朊病毒污染的風險；與血清收集相關的高成本和倫理問題；對可能還含有生長抑制劑。高品質Growth factors&cytokines產品具有以下特點：(A) 嚴格條件下的高純度生產確保質量保持一致，每批批次純度≥95％通過SDS-PAGE. (B) 內毒素最小 – Limulus Amebocyte Lysate (LAL) assay。低於1 EU/ug recombinant protein。(C) 確保每一批生物活性。
重組人白血病抑制因子（LIF） (CHO Cell) | 貨號Z101345
LIF、分化刺激因子、D因子、黑素瘤來源的LPL抑制劑、MLPLI、INN = Emfilermin，HILDA、重組人白血病抑制因子（ Leukemia Inhibitory Factor , LIF）
產品介紹: LIF是以可溶性(soluble)和基質結合形式( matrix-bound forms)存在的多功能分泌型糖蛋白(secreted glycoprotein)。 它顯示生物活性(biologic activities )，從骨髓白血病細胞(myeloid leukemic cells )分化為巨噬細胞譜系(macrophage lineage )，對骨代謝( bone metabolism)，炎症( inflammation)，神經發育(neural development)，胚胎形成( embryogenesis)和植入( implantation)維持的影響。 現在清楚的是，LIF在結構和作用機制上都與細胞因子白細胞介素IL-6家族( interleukin IL-6 family)有關，細胞因子也包括IL-11，睫狀神經營養因子( ciliary neurotrophic factor)，制瘤素M ( oncostatin M)和心肌營養因子1(cardiotrophin 1)。這些細胞因子的作用介導 通過特定的細胞表面受體由獨特的鍊和共享的信號轉導子單元gp130組成。
aFGF重組蛋白 | IL-2重組蛋白 | 幹細胞因子（KITLG） | 重組人白血病抑制因子（LIF） | 重組人Human Noggin (NOG) | TNF-a | BMP2
| Gene Symbol | LIF |
| Gene ID | 3976 |
| Accession No. | P15018 |
| Source | CHO cells |
| Appearance | Lyophilized Powder |
| Molecular Weight | 20.0 kDa |
| Endotoxin Level | <1.0 EU/μg of recombinant protein as determined by the LAL method. |
| Purity | >95% as determined by SDS-PAGE |
| Bioactivity | The ED(50) was determined by the dose-dependent differentiation of M1 myeloid leukemic cells was found to be in the range of 0.01 ng/mL. |
| Formulation | Recombinant Leukemia Inhibitory Factor was lyophilized from a 0.2 μm filtered PBS pH 4.5 |
| Product | Source | Size | Cat. No. |
| Recombinant Human THPO | HEK293 | 10 µg | Z103085 |
| Recombinant Human THPO | HEK293 | 100 µg | Z103087 |
| Recombinant Human LIF | E. coli | 10 µg | Z100605 |
| Recombinant Mouse LIF | E. coli | 10 µg | Z200195 |
| Recombinant Human SERPINF1 | E. coli | 10 µg | Z100765 |
| Recombinant Human MIF | E. coli | 25 µg | Z100915 |
| Recombinant Mouse LIF | CHO cells | 100 µg | Z200485 |
| Recombinant Human LIF | CHO cells | 50 µg | Z101345 |
| Recombinant Human THPO | E. coli | 10 µg | Z101515 |
| Recombinant Mouse THPO | E. coli | 10 µg | Z200535 |
| Recombinant Mouse LIF | E. coli | 1.0 mg | Z200199 |
| Recombinant Human MIF | E. coli | 1.0 mg | Z100919 |
| Recombinant Human LIF | E. coli | 1.0 mg | Z100609 |
| Recombinant Human SERPINF1 | E. coli | 1.0 mg | Z100769 |
| Recombinant Human THPO | E. coli | 1.0 mg | Z101519 |
| Recombinant Mouse THPO | E. coli | 1.0 mg | Z200539 |
| Recombinant Human LIF | E. coli | 100 µg | Z100607 |
| Recombinant Human MIF | E. coli | 100 µg | Z100917 |
| Recombinant Human SERPINF1 | E. coli | 500 µg | Z100767 |
| Recombinant Mouse LIF | E. coli | 100 µg | Z200197 |
| Recombinant Porcine LIF | E. coli | 10 µg | Z400015 |
| Recombinant Porcine LIF | E. coli | 1.0 mg | Z400019 |
| Recombinant Porcine LIF | E. coli | 100 µg | Z400017 |