aFGF重組蛋白 | 293細胞表達Growth Factors貨號Z100005
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【Growth factors&cytokines細胞生長因子】 CHO cell/HEK293 /E.coli表現系統
Growth factors生長因子和cytokines細胞因子，是天然存在的signaling molecules信號分子，它們是高等生物細胞之間攜帶調節信號的關鍵因素。儘管細胞因子主要與immune system housekeeping免疫系統相關，生長因子在生物體的發育和成熟階段調節具廣泛的過程；不受控制的生長因子激活通常與oncogenesis腫瘤發生相關。生長因子和細胞因子對於細胞的許多功能是不可缺少的。傳統的細胞生物學實驗使用動物血清作為正常細胞代謝所需的生長因子和營養來源。但是，使用動物血清，容易增加病毒，支原體和朊病毒污染的風險；與血清收集相關的高成本和倫理問題；對可能還含有生長抑制劑。高品質Growth factors&cytokines產品具有以下特點：(A) 嚴格條件下的高純度生產確保質量保持一致，每批批次純度≥95％通過SDS-PAGE. (B) 內毒素最小 – Limulus Amebocyte Lysate (LAL) assay。低於1 EU/ug recombinant protein。(C) 確保每一批生物活性。
aFGF重組蛋白 | 293細胞表達Growth Factors貨號 Z100005
aFGF, FGF-1, Heparin-binding growth factor 1, HBGF-1, Endothelial cell growth factor, ECGF-beta, FGFA, FGF1
產品介紹: aFGF和bFGF顯示55％的同源性，然而限於幾個功能域。 通過X射線晶體學顯示的aFGF的結構顯示出與IL1相似的折疊結構。 因為aFGF與bFGF相同的受體結合，所以aFGF或多或少顯示相同的活性譜。然而，在類似的測定中，它通常比bFGF活性低。 FGF受體由至少四種受體酪氨酸激酶組成的基因家族編碼，其轉導在與細胞生長和分化相關的各種發育和生理過程中重要的信號。 重組人FGF1是16kDa的單一多肽。
aFGF重組蛋白 | IL-2重組蛋白 | 幹細胞因子（KITLG） | 重組人白血病抑制因子（LIF） | 重組人Human Noggin (NOG) | TNF-a | BMP2
| Gene Symbol | FGF1 |
| Gene ID | 9158 |
| Accession No. | P05230 |
| Source | E. coli |
| Appearance | Lyophilized Powder |
| Molecular Weight | 16.0 kDa |
| Endotoxin Level | <1.0 EU/μg of recombinant protein as determined by the LAL method |
| Purity | >95% as determined by SDS-PAGE |
| Gel Image | |
| Bioactivity | The ED50 as determined by the dose-dependent stimulation of mouse fibroblasts was <0.5ng/ml |
| Bioactivity Data | |
| Formulation | Lyophilized from a 0.2 μm filtered solution in PBS |
| Reconstitution | A quick spin of the vial followed by reconstitution in distilled water to a concentration not less than 0.1 mg/mL. This solution can then be diluted into other buffers. |
| Product | Source | Size | Cat. No. |
| Recombinant Human FGF1 | E. coli | 50 µg | Z100005 |
| Recombinant Mouse FGF1 | E. coli | 50 µg | Z200005 |
| Recombinant Human FGF10 | E. coli | 25 µg | Z100205 |
| Recombinant Human FGF16 | E. coli | 20 µg | Z102295 |
| Recombinant Human FGF17 | E. coli | 20 µg | Z102305 |
| Recombinant Human FGF18 | E. coli | 20 µg | Z102315 |
| Recombinant Human FGF19 | E. coli | 25 µg | Z102325 |
| Recombinant Human FGF10 | E. coli | 1.0 mg | Z100209 |
| Recombinant Human FGF1 | E. coli | 1.0 mg | Z100009 |
| Recombinant Mouse FGF1 | E. coli | 1.0 mg | Z200009 |
| Recombinant Human FGF17 | E. coli | 1.0 mg | Z102309 |
| Recombinant Human FGF19 | E. coli | 1.0 mg | Z102329 |
| Recombinant Human FGF16 | E. coli | 1.0 mg | Z102299 |
| Recombinant Human FGF1 | E. coli | 250 µg | Z100007 |
| Recombinant Human FGF10 | E. coli | 100 µg | Z100207 |
| Recombinant Human FGF16 | E. coli | 100 µg | Z102297 |
| Recombinant Human FGF17 | E. coli | 100 µg | Z102307 |
| Recombinant Human FGF18 | E. coli | 200 µg | Z102317 |
| Recombinant Human FGF18 | E. coli | 1.0 mg | Z102319 |
| Recombinant Mouse FGF1 | E. coli | 200 µg | Z200007 |