非達黴素(Fidaxomycin) | CAS#873857-62-6貨號2832

產品描述: 非達黴素(Fidaxomycin)是一種天然的大環抗生素(macrocyclic antibiotic)和RNA聚合酶抑制劑(RNA polymerase inhibitor)，與革蘭氏陰性菌(Gram-negative bacteria)相比，對革蘭氏陽性菌(Gram-positive bacteria)具有選擇性（IC₅₀s分別為0.4和6μM）。它顯示出對大多數革蘭氏陽性細菌(Gram-positive bacteria)有效的抗菌活性，並有效靶向革蘭氏陽性(Gram-positive bacteria) 艱難梭菌（MIC = 12 ng / ml）。還顯示出對耐多藥結核分枝桿菌(multidrug-resistant Mycobacterium tuberculosis) 具有優異的殺菌活性。

穀胱甘肽過氧化物酶活性測定 |  FRAP檢測 | 總膠原蛋白分析 | Dopamine多巴胺檢測 | 三酸甘油酯分析 | Cholesterol Efflux膽固醇排出螢光分析 | 脂質過氧化（MDA）測定 | 支鏈氨基酸 BCAA檢測

Alternate Name	3E,5E,8S,9E,11S,12R,13E,15E,18S)-3-[[[6-Deoxy-4-O-(3,5-dichloro-2-ethyl-4,6-dihydroxybenzoyl)-2-O-methyl-β-D-mannopyranosyl]oxy]methyl]-12-[[6-deoxy-5-C-methyl-4-O-(2-methyl-1-oxopropyl)-β-D-lyxo-hexopyranosyl]oxy]-11-ethyl-8-hydroxy-18-[(1R)-1-hydroxyethyl]-9,13,15-trimethyl-oxacyclooctadeca-3,5,9,13,15-pentaen-2-one; Clostomicin B1; Dificid; Dificlir; Fidaxomicin; Fidaxomycin; Lipiarmicin; Lipiarmycin; Lipiarmycin A 3; OPT 80; PAR 01; PAR 101; R-Tiacumicin B; Tiacumicin B
Appearance	White solid
CAS #	873857-62-6
Molecular Formula	C₅₂H₇₄Cl₂O₁₈
Molecular Weight	1058.04
Purity	≥98%
Solubility	DMSO
SMILES	CCC1C=C(C(CC=CC=C(C(=O)OC(CC=C(C=C(C1OC2C(C(C(C(O2)(C)C)OC(=O)C(C)C)O)O)C)C)C(C)O)COC3C(C(C (C(O3)C)OC(=O)C4=C(C(=C(C(=C4O)Cl)O)Cl)CC)O)OC)O)C

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