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Phorbol-12-myristate 13-acetate (PMA) | 貨號1544-5 (abcam ab120297)

這是最常用的佛波酯 (phorbol ester)。它結合併激活蛋白激酶C(activates protein kinase C)，在細胞和組織中引起廣泛的作用，並且是一種非常有效的小鼠皮膚腫瘤啟動子(skin tumor promoter.)。抑制Fas抗原誘導的凋亡(apoptosis induced)，但誘導HL-60早幼粒細胞白血病細胞凋亡。 引用文獻Lu et al., IL-17A, But Not IL-17F, Is Indispensable for Airway Vascular Remodeling Induced by Exaggerated Th17 Cell Responses in Prolonged Ovalbumin-Challenged Mice. J. Immunol., Apr 2015; 194: 3557 – 3566.

穀胱甘肽過氧化物酶活性測定 |  FRAP檢測 | 總膠原蛋白分析 | Dopamine多巴胺檢測 | 三酸甘油酯分析 | Cholesterol Efflux膽固醇排出螢光分析 | 脂質過氧化（MDA）測定 | 支鏈氨基酸 BCAA檢測

引用文獻 Lu et al., IL-17A, But Not IL-17F, Is Indispensable for Airway Vascular Remodeling Induced by Exaggerated Th17 Cell Responses in Prolonged Ovalbumin-Challenged Mice. J. Immunol., Apr 2015; 194: 3557 – 3566.

Cat # +Size	1544-5 (abcam ab120297)
Size	5 mg
Alternate Name	PMA, 12-O-Tetradecanoylphorbol 13-acetate,TPA, 4β,9α,12β,13α,20-Pentahydroxytiglia-1,6-dien-3-one 12-tetradecanoate 13-acetate
Appearance	White solid
CAS #	16561-29-8
Molecular Formula	C₃₆H₅₆O₈
Molecular Weight	616.83
Purity	>99%
Solubility	DMSO or EtOH
SMILES	CCCCCCCCCCCCCC(=O)OC1C(C2(C(C=C(CC3(C2C=C(C3=O)C)O)CO)C4C1(C4(C)C)OC(=O)C)O)C
InChi	InChI=1S/C36H56O8/c1-7-8-9-10-11-12-13-14-15-16-17-18-29(39)43-32-24(3)35(42)27(30-33(5,6)36(30,32)44-25(4)38)20-26(22-37)21-34(41)28(35)19-23(2)31(34)40/h19-20,24,27-28,30,32,37,41-42H,7-18,21-22H2,1-6H3/t24-,27+,28-,30-,32-,34-,35-,36-/m1/s1
InChi Key	PHEDXBVPIONUQT-RGYGYFBISA-N
PubChem CID	27924
MDL Number	MFCD00036736
Handling	Protect from light
Storage Conditions	-20°C
Shipping Conditions	Gel Pack
USAGE	For Research Use Only! Not For Use in Humans.

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