Caspase 3單株抗體|Caspase-3 Antibody 貨號3004-100

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特點
Caspase-3 Antibody (Clone C33)
產品介紹: Caspase家族的半胱氨酸蛋白酶在細胞凋亡中扮演關鍵作用。 Caspase-3是Caspase家族成員中研究最廣泛的凋亡蛋白。 Caspase-3被合成為無活性的前酶,其通過自身蛋白水解和/或通過另一種上游蛋白酶切割而在經歷凋亡的細胞中加工。 加工形式的胱天蛋白酶-3由大(17kD)和小(12kD)亞基組成,它們結合形成活性酶。 活性胱天蛋白酶-3蛋白水解切割並活化其他半胱天冬酶,以及細胞中的相關靶標(例如,PARP和DFF)。

| Cat # +Size | 3004-100 |
| Size | 100 µg |
| Alternate Name | CPP32 ,CASP3, apopain, procaspase3,CPP32B,SCA-1,CPP-32,Apopain,Yama |
| Host | Mouse |
| Antibody Type | Monoclonal |
| Isotype | Mouse IgG1 |
| Immunogen | Recombinant human Caspase-3 |
| Accession # | P42574 |
| Gene ID | 836 |
| Appearance | Colorless liquid |
| Concentration | 0.2 mg/ml |
| Formulation | 100 µg (200 µg/ml) in PBS containing 50% glycerol, 0.5 mg/ml BSA and 0.01% thimerosal. |
| Purification | Affinity purified |
| Species Reactivity | Human, mouse, rat |
| Application | Western blot |
| Application & Usage | Western blotting (0.5-4 µg/ml). The antibody recognizes both proform and the cleaved large fragment of caspase-3 in samples of human, mouse and rat origins. However, the optimal conditions should be determined individually. |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
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