亞精胺或精胺 N1-乙醯轉移酶 1 單株小鼠抗體 (CPTC-SAT1-3) 貨號2273
Spermidine or Spermine N1-Acetyltransferase 1 Monoclonal Mouse Antibody (CPTC-SAT1-3)

亞精胺(Spermidine)/精胺N1-乙醯轉移酶1(spermine N1-acetyltransferase 1 )（SAT1或SSAT1）是多胺(polyamines)分解代謝中的關鍵調節酶，催化亞精胺(spermidine)或精胺乙醯化(spermine)生成N1-乙醯亞精胺(N1-acetyl spermidine )或N1-乙醯精胺( N1-acetyl spermine)，以及N1，N12-二乙醯精胺(N1, N12-diacetylspermine)。SAT1 的細胞水平通常極低，但它會被多種刺激迅速誘導，包括多胺(polyamines)、多胺類似物(polyamine analogs)、有毒化學物質(toxic chemicals)、某些藥物(certain drugs)和生長因子。據報道，Epstein-Barr 病毒陽性(Epstein-Barr virus positive)的 Burkitt 淋巴瘤細胞中 SAT1 下調。一抗(Primary antibodies )可以是純化的，或帶有精選的螢光 CF® 染料和其他標記。CF® 染料具有卓越的亮度和光穩定性。請參閱CF® 染料手冊以了解更多資訊。注意：不建議使用 CF®405S 和 CF®405M 等藍色螢光染料的結合物來檢測低豐度目標，因為藍色染料的螢光較低，並且比其他染料顏色會產生更高的非特異性背景( non-specific background)。

Antibody number	#2273
Antibody reactivity (target)	Spermidine or Spermine N1-Acetyltransferase 1
Antibody type	Primary
Host species	Mouse
Clonality	Monoclonal
Clone	CPTC-SAT1-3
Isotype	IgG2a, kappa
Molecular weight	20 kDa
Synonyms	DC21; Diamine acetyltransferase 1; Diamine N acetyltransferase 1; EC 2.3.1.57; KDSD; KSDX; Polyamine N acetyltransferase 1; Putrescine acetyltransferase; SAT1; spermidine/spermine N1 acetyltransferase alpha; SSAT; SSAT1
Human gene symbol	SAT1
Entrez gene ID	6303
SwissProt	P21673
Unigene	28491
Immunogen	Recombinant full-length human SAT1 protein
Antibody target cellular localization	Cytoplasmic
Species reactivity	Human
Antibody application notes	For coating for ELISA, order Ab without BSA, Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody, Optimal dilution and staining procedure for a specific application should be determined by user, Recommended starting concentrations for titration are 1-2 ug/mL for most applications, or 1 ug/million cells/100 uL for flow cytometry
Positive control	Human liver tissue lysate; human tonsil or kidney.
Shipping condition	Room temperature
Storage Conditions	Store at 2 to 8 °C, Protect fluorescent conjugates from light, Note: store BSA-free antibodies at -10 to -35 °C
Regulatory status	For research use only (RUO)
Antibody/conjugate formulation	Conjugates: 0.1 mg/mL in PBS/0.1% BSA/0.05% azide, HRP conjugates: 0.1 mg/mL in PBS/0.05% BSA, Purified: 0.2 mg/mL in PBS/0.05% BSA/0.05% azide, Purified, BSA-free: 1 mg/mL in PBS without azide
Validated in protein array	Monospecific
Shelf life	Guaranteed for at least 24 months from date of receipt when stored as recommended
Tumor expression	Leukemia/lymphoma

Catalog Number Key for Primary Antibody Conjugates

Antibody # prefix	Conjugation	Ex/Em (nm)	Laser line	Detection channel	Dye Features
BNC04	CF®405S	404/431	405	DAPI (microscopy), AF405	CF®405S Features
BNC88	CF®488A	490/515	488	GFP, FITC	CF®488A Features
BNC68	CF®568	562/583	532, 561	RFP, TRITC	CF®568 Features
BNC94	CF®594	593/614	561	Texas Red®	CF®594 Features
BNC40	CF®640R	642/662	633-640	Cy®5	CF®640R Features
BNC47	CF®647	650/665	633-640	Cy®5	CF®647 Features
BNCB	Biotin	N/A	N/A	N/A
BNUB	Purified	N/A	N/A	N/A
BNUM	Purified, BSA-free	N/A	N/A	N/A

Alexa Fluor, Pacific Blue, Pacific Orange, and Texas Red are trademarks or registered trademarks of Thermo Fisher Scientific; Cy is a registered trademark of Cytiva; IRDye, LI-COR, and Odyssey are registered trademarks of LI-COR Bioscience.

 

Biotium 提供範圍廣泛的螢光探針用於研究凋亡細胞(Apotosis)

The NucView® Caspase-3 Substrate comes in 3 colors, and measures caspase activity in real time, in live cells. MitoView™ 633 can measure the decrease in mitochondria membrane potential that occurs in early apoptosis. CF® Dye Annexin V conjugates come in many color options, and label PS on the membranes of late apoptotic cells. We also offer kits containing combinations of these probes.