Angiotensin-Converting Enzyme (ACE) Inhibitors抑制劑 | Captopril抑制劑 | 貨號: B1187-5G

An angiotensin-converting enzyme (ACE) inhibitor

Captopril是血管緊張素轉化酶（ACE）抑制劑（IC 50= 0.022μM）。也抑制bifunctional Zn2+-containing leukotriene A4可逆地與競爭性水解/氨（LTA4水解酶）（Ki =6.0μM or leukotriene B4> formation and Ki = 60 nM for L-lysine-p-nitroanilide)。體內顯示血管舒張和抗高血壓作用。臨床上有用的抗高血壓藥物

Captopril is an angiotensin-converting enzyme (ACE) inhibitor (IC₅₀ = 0.022 μM). Also inhibits the bifunctional Zn2+-containing leukotriene A4 hydrolase/aminopeptidase (LTA4 hydrolase) reversibly and competitively (Ki = 6.0 μM for leukotriene B4> formation and Ki = 60 nM for L-lysine-p-nitroanilide). Displays vasodilatory and antihypertensive effects in vivo. Clinically useful antihypertensive agent.

Molecular Formula: C₉H₁₅NO₃S

Molecular Weight: 217.28

Purity: ≥98% by HPLC

Solubility: DMSO (20 mg/ml)

Catalog #	Product Name+	Size
9687-100	ACE2 Inhibitor, DX600	100 µg
9687-500	ACE2 Inhibitor, DX600	500 µg
9687-1000	ACE2 Inhibitor, DX600	1 mg
B1187-1G	Captopril	1 g
B1187-5G	Captopril	5 g

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