ODM-201新一代AR拮抗劑 | Androgen Receptor Antagonists Biovision 貨號: 9668-25
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Androgen Receptor Antagonists抑制劑 | ODM-201抑制劑 | 貨號: 9668-25
A new-generation, potent and selective androgen receptor (AR) antagonist
ODM-201是新一代，有效的和選擇性之雄激素受體（AR）拮抗劑（Ki = 11 nM）。在AR過度之HS-HEK293細胞，ODM-201抑制過度表達AR之雄激素誘導之nuclear translocation。在VCaP 細胞系內源性AR基因擴增和AR過度表達，ODM-201抑制雄激素誘導的細胞增殖 (230 Nm IC 50)
ODM-201 is a new-generation, potent and selective androgen receptor (AR) antagonist (Ki = 11 nM). In AR overexpressing HS-HEK293 cells, ODM-201 inhibits the androgen-induced nuclear translocation of overexpressed AR. In the VCaP cell line with endogenous AR gene amplification and AR overexpression, ODM-201 inhibits androgen-induced cell proliferation with IC₅₀ value of 230 Nm
Molecular Formula: C₁₉H₁₉ClN₆O₂
Molecular Weight: 389.85
Purity: ≥98% by HPLC
Solubility: DMSO
| Catalog # | Product Name+ | Size |
| 9535-5 | ARN-509 | 5 mg |
| 9535-25 | ARN-509 | 25 mg |
| 9479-10 | MDV-3100 | 10 mg |
| 9479-50 | MDV-3100 | 50 mg |
| 9668-5 | ODM-201 | 5 mg |
| 9668-25 | ODM-201 | 25 mg |
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