FDP (high purity) | CAS#217305-49-2 Biotium 貨號#10030 (5MG) 

FDP（二磷酸螢光素，四銨鹽，高純度）是最敏感的螢光鹼性磷酸酶底物。它也是蛋白酪氨酸磷酸酶 (protein tyrosine phosphatase, PTPase) 的優異底物，因此是 PTPase 抑制劑高通量篩選 (HTS) 的首選底物。

FDP (fluorescein diphosphate, tetraammonium salt, high purity) is the most sensitive fluorogenic alkaline phosphatase substrate. It is also an excellent substrate for protein tyrosine phosphatase (PTPase) and thus the substrate of choice in the high throughput screening (HTS) for PTPase inhibitor. FDP itself is colorless, but the end product of the enzymatic reaction is the green fluorescent dye fluorescein.

• λ_Ex/λ_Em = 490/514 nm (end product)
• ε = 90,000 (end product)
• Off-white solid soluble in water
• Store at -20°C and protect from light, especially in solution
• C₂₀H₂₆N₄O₁₁P₂
• MW: 560.39
• [217305-49-2]

1. Appl Environ Microbiol 64, 1526 (1998).

2. Biol Res 27, 241 (1994).

3. Anal Biochem 285, 58 (2000).

4. J Biomol Screen 4, 327 (1999).

5. Proc Natl Acad Sci USA 93, 3068 (1996).

Biotium 提供範圍廣泛的螢光探針用於研究凋亡細胞(Apotosis)

The NucView® Caspase-3 Substrate comes in 3 colors, and measures caspase activity in real time, in live cells. MitoView™ 633 can measure the decrease in mitochondria membrane potential that occurs in early apoptosis. CF® Dye Annexin V conjugates come in many color options, and label PS on the membranes of late apoptotic cells. We also offer kits containing combinations of these probes.