Caspase-9 多株抗體 | 胱天蛋白酶-9多株抗體Biovision貨號3016-100
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特點
胱天蛋白酶-9是胱天蛋白酶家族成員中最重要的胱天蛋白酶之一。 合成胱天蛋白酶-9作為在經歷細胞凋亡的細胞中處理的無活性原酶。 處理的半胱天冬酶-9由大（32-35kD）和小（10kD）亞基組成，其形成活性酶。 活化的半胱天冬酶-9又切割並激活胱天蛋白酶-3，其是導致凋亡中許多關鍵蛋白質的蛋白水解切割的蛋白酶之一。
相關商品 Z-DEVD-FMK | Caspase-3 (Active) 抗體 | pGB Caspase-3 siRNA 載體 | DEVD-pNA | Caspase-3抑制劑藥物篩選
| Antibody Target | Caspase-9 |
| Alternate Name | CASP-9 , EC 3.4.22.62 , ICE-like apoptotic protease 6 ,ICE-LAP6 ,Apoptotic protease Mch-6 ,Apoptotic protease-activating factor 3 , Apaf-3 |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Synthetic peptide surrounding amino acid 290 of human caspase-9 |
| Accession # | RP11-265F14.3 |
| Gene ID | 842 |
| Appearance | Colorless liquid |
| Concentration | 0.5 mg/ml |
| Formulation | In PBS pH 7.2, containing 30% glycerol, 0.5% BSA, 5 mM EDTA and 0.03% Proclin |
| Purification | Affinity purified |
| Species Reactivity | Human, mouse, rat, hamster, bovine, rabbit, pig |
| Application | Western blot |
| Application & Usage | Western blotting (0.5-4 µg/ml). However, the optimal conditions should be determined individually. The antibody detects proform (~46 kDa), intermediate (~33-36 kDa), and the fully cleaved (~20-25 kDa) caspase-9. |