Fc Silent™ Antibodies: Turning down the background noise

Fc Silent 抗體 | 只要訊號不要雜訊 (Engineered Fc Domain)

Absolute Antibody 提供一系列抗體商品，其中Fc Silent™ Antibodies系列；能有效降低非特異性Fc結合。Fc Silent™技術，為應用生物工程技術，將Fc receptors (FcγR, FcR)點突變，進而中止抗體與ADCC的功能；有效降低Fc所造成的背景訊號。

Fc Silent™抗體應用於免疫細胞時flow cytometry、immunohistochemistry (IHC)資料顯示，有效降低非特異性之Fc結合，所造成的背景值。(訂購抗體前，請確認選擇抗體是否有Fc Silent™修飾標誌)

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Eptiope Tag系列抗體  c-Myc單株抗體 | GCN4單株抗體 | His Tag單株抗體 | Rhodopsin單株抗體 | Rim ABCTag單株抗體 | Tag54 Tag單株抗體 | V5 T ag單株抗體 |

【GCN4 Epitope Tag系列商品】 | Anti-GCN4 [C11L34]單株抗體, 200ug

 Description:  Recombinant monoclonal antibody to GCN4. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the scFv C11L34.

UniProt Accession Number of Target Protein: P03069

Alternative Name(s) of Target: General Control Protein 4 Immunogen: Biotinylated GCN4-peptide (HLENEVARLKK).

Specificity: This antibody binds to the HLENEVARLKK peptide from the leucine-zipper domain of the S. cerevisiae GCN4 transcriptional activator with a Kd of 5 pM.

Application Notes: This antibody binds to the GCN4-leucine zipper peptide, which is part of the dimerisation- and DNA-binding domain of the transcriptional activator GCN4 in S. cerevisiae.

Product	Expected Species Reactivity	Isotype/Format	Modification	Products
Ab00436-1.1 Anti-GCN4 [C11L34]	S. cerevisiae	Mouse IgG1		Purified
Ab00436-23.0 Anti-GCN4 [C11L34]	S. cerevisiae	Rabbit IgG		Purified
Ab00436-1.4 Anti-GCN4 [C11L34]	S. cerevisiae	Mouse IgG1	Fc Silent™	Purified