Rhodopsin Epitope Tag系列抗體 | Rhodopsin單株抗體, 200ug

代理廠牌：
原廠連結：
相關下載：

特點

Fc Silent™ Antibodies: Turning down the background noise

Fc Silent 抗體 | 只要訊號不要雜訊 (Engineered Fc Domain)

Absolute Antibody 提供一系列抗體商品，其中Fc Silent™ Antibodies系列；能有效降低非特異性Fc結合。Fc Silent™技術，為應用生物工程技術，將Fc receptors (FcγR, FcR)點突變，進而中止抗體與ADCC的功能；有效降低Fc所造成的背景訊號。

Fc Silent™抗體應用於免疫細胞時flow cytometry、immunohistochemistry (IHC)資料顯示，有效降低非特異性之Fc結合，所造成的背景值。(訂購抗體前，請確認選擇抗體是否有Fc Silent™修飾標誌)

【Rhodopsin Epitope Tag系列商品】 | Anti-Rhodopsin [Rho 1D4]單株抗體, 200ug
Description: Recombinant monoclonal antibody to Rhodopsin. Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma Rho 1D4.

Alternative Name(s) of Target: Visual Purple Immunogen: Bleached bovine rod outer segment (ROS).

Specificity: The antibody binds to the C-terminus of rhodopsin on the cytoplasmic side of disk membranes. The epitope has the following amino acid sequence: ‘TETSQVAPA’. A limitation of the 1D4 tag, however, is that it has to be placed at the C-terminus of a protein. This is because the Rho1D4 monoclonal antibody requires a free carboxylate group for high affinity binding. Amidation of the carboxyl group lowers its immunoreactivity to the Rho1D4 antibody by over 100 fold.

Application Notes: The antibody binds to the C-terminus of rhodopsin on the cytoplasmic side of disk membranes. Rhodopsin is the major pigment in rod photoreceptors and belongs to the family of G-protein-coupled receptors (GPCRs). The linear epitope (TETSQVAPA) can be used as a protein tag.

Product	Expected Species Reactivity	Isotype/Format	Modification	Products
Ab00337-1.1 Anti-Rhodopsin [Rho 1D4]	Mouse; Rat; Cow; Human, Zebrafish, Amphibians	Mouse IgG1		Purified
Ab00337-1.4 Anti-Rhodopsin [Rho 1D4]	Mouse; Rat; Cow; Human, Zebrafish, Amphibians	Mouse IgG1	Fc Silent™	Purified
Ab00337-10.6 Anti-Rhodopsin [Rho 1D4]	Mouse; Rat; Cow; Human, Zebrafish, Amphibians	Human Fab fragment	His-Tagged	Purified
Ab00337-23.0 Anti-Rhodopsin [Rho 1D4]	Mouse; Rat; Cow; Human, Zebrafish, Amphibians	Rabbit IgG		Purified
Ab00337-10.0 Anti-Rhodopsin [Rho 1D4]	Mouse; Rat; Cow; Human, Zebrafish, Amphibians	Human IgG1		Purified
Ab00337-10.3 Anti-Rhodopsin [Rho 1D4]	Mouse; Rat; Cow; Human, Zebrafish, Amphibians	Human IgG1	Fc Silent™	Purified
Ab00337-10.7 Anti-Rhodopsin [Rho 1D4]	Mouse; Rat; Cow; Human, Zebrafish, Amphibians	Human F(ab’)2	AbFab2™	Purified
Ab00337-22.0 Anti-Rhodopsin [Rho 1D4]	Mouse; Rat; Cow; Human, Zebrafish, Amphibians	Hamster (Armenian) IgG		Purified
Ab00337-24.1 Anti-Rhodopsin [Rho 1D4]	Mouse; Rat; Cow; Human, Zebrafish, Amphibians	Goat IgG		Purified
Ab00337-6.1 Anti-Rhodopsin [Rho 1D4]	Mouse; Rat; Cow; Human, Zebrafish, Amphibians	Rat IgG1		Purified
Ab00337-6.4 Anti-Rhodopsin [Rho 1D4]	Mouse; Rat; Cow; Human, Zebrafish, Amphibians	Rat IgG1	Fc Silent™	Purified

↑回到頁首↑