泛艾霉素 (Pirarubicin) | CAS#72496-41-4 APExBIO貨號B2295
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Rapamycin)| Romidepsin (FK228, depsipeptide) | Daptomycin | Pirarubicin | Tunicamycin
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泛艾霉素 (Pirarubicin) | CAS#72496-41-4 APExBIO貨號B2295
anthracycline anti-neoplastic doxorubicin
泛艾霉素(Tunicamycin) Pirarubicin is an analogue of the anthracycline anti-neoplastic doxorubicin. Intercalates into DNA and interacts with Topo II (topoisomerase II) and supressing DNA replication. Pirarubicin is an inhibitor of Topo II. 泛艾霉素(Tunicamycin)是蒽環類(anthracycline)抗腫瘤多柔比星(anti-neoplastic doxorubicin)的類似物。 嵌入 DNA 並與 Topo II(拓撲異構酶 II)相互作用並抑制 DNA 複製(supressing DNA replication)。 Pirarubicin 是 Topo II 的抑制劑。
- Krai Daowtak,Suchart Kothan,et al. “In vitro evaluation of P-glycoprotein functions in human neuroblastoma cell lines.” Journal of Associated Medical Sciences.Vol 51 No 2 (2018): May-August.
Physical Appearance | A solid |
Storage | Store at -20°C |
M.Wt | 627.64 |
Cas No. | 72496-41-4 |
Formula | C32H37NO12 |
Solubility | insoluble in H2O; insoluble in EtOH; ≥7.65 mg/mL in DMSO |
Chemical Name | 7-[4-amino-6-methyl-5-(oxan-2-yloxy)oxan-2-yl]oxy-6,9,11-trihydroxy-9-(2-hydroxyacetyl)-4-methoxy-8,10-dihydro-7H-tetracene-5,12-dione |
SDF | Download SDF |
Canonical SMILES | CC1C(C(CC(O1)OC2CC(CC3=C(C4=C(C(=C23)O)C(=O)C5=C(C4=O)C=CC=C5OC)O)(C(=O)CO)O)N)OC6CCCCO6 |
Shipping Condition | Ship with blue ice, or upon other requests. |
General tips | For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. We do not recommend long-term storage for the solution, please use it up soon. |
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品項 | CAS# | #貨號 | 應用 |
Romidepsin (FK228, depsipeptide) |
CAS#128517-07-7
|
貨號A8173 | HDAC1/HDAC2,強效和選擇性抑制劑 |
Pirarubicin | CAS#72496-41-4 | 貨號B2295 | anthracycline anti-neoplastic doxorubicin |
Tunicamycin | CAS# 15663-27-1 |
貨號A8321
|
高效、廣譜的化療藥物 |
Azithromycin | CAS#83905-01-5 | 貨號A2213 | Hsp90 inhibitor |
Bleomycin Sulfate |
CAS# 9041-93-4
|
貨號B1398 | Antibiotic by inhibiting protein synthesis |
Nystatin (Fungicidin) | CAS#1400-61-9 | 貨號B1993 | antifungal antibiotic |
Rapamycin | CAS#53123-88-9 | 貨號A8167 | Original antifungal antibiotic |
Daptomycin | CAS#103060-53-3 | 貨號A1206 | Calcium-dependent antibiotic |