溶菌酶抑制劑篩選| Lysozyme Inhibitor Screening Kit貨號K237-100
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特點
Lysozyme Inhibitor Screening Kit
產品描述：Lysozyme溶菌酶（EC 3.2.1.17），也稱為muramidase胞壁質酶或N-乙酰胞壁酰胺聚醣水解酶 (N-acetylmuramide glycanhydrolase) ，Lysozyme溶菌酶廣泛存在於各種生物液體中，如tears淚液，saliva唾液和tissues組織。它可作為先天免疫系統的關鍵effector。它也是由某些癌合成的。癌細胞（尤其是myelomonocytic leukemia髓單核細胞白血病）過量產生Lysozyme溶菌酶導致更高水平的Lysozyme溶菌酶導致renal failure腎衰竭。已經證明溶菌酶的表達水平是獨立的t prognostic factor預後因子，其可用於預測乳腺癌患者的relapse-free survival無復發存活和overall survival總體存活。因此，lysozyme inhibitors溶菌酶抑制劑可構成開發抗炎和/或抗腫瘤藥物的有吸引力的潛在靶標。 BioVision的溶菌酶抑制劑篩選試劑盒使用N，N’，N” – Triacetylchitotriose-一種競爭性抑制劑，可與溶菌酶的活性位點結合。該抑制劑降低了溶菌酶對水解螢光底物的催化能力，提供簡單，快速，靈敏和可靠的測試，適用於篩選溶菌酶抑制劑。
| Cat # +Size | K237-100 |
| Size | 100 assays |
| Detection Method | Fluorescence (Ex/Em = 360/445 nm) |
| Species Reactivity | Mammalian |
| Applications | The kit provides a rapid, simple, sensitive, and reliable test suitable for high throughput screening of Lysozyme inhibitors. Inhibitor control (N,N’,N”-Triacetylchitotriose) is included to compare the efficacy of test inhibitors. |
| Features & Benefits | • Simple procedure • Fast and convenient • The assay is sensitive, stable and high-throughput adaptable |
| Kit Components | • Lysozyme Assay Buffer • Lysozyme substrate (in DMSO) • Lysozyme (lyophilized) • N,N’,N”-Triacetylchitotriose |
| Storage Conditions | -20°C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |
溶菌酶ELISA檢測套組 | 溶菌酶活性檢測 | 溶菌酶抗體 | 溶菌酶抑制劑篩選