Z-DEVD-FMK肽抑制劑 | Caspase-3 Inhibitor Z-DEVD-FMK貨號1009
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特點
Caspase-3 Inhibitor Z-DEVD-FMK
產品描述：Z-DEVD-FMK一種合成肽抑制劑，其不可逆地抑制半胱天冬酶-3和相關蛋白酶/半胱天冬酶活性並阻斷細胞凋亡。 DEVD是聚（ADP-核糖）聚合酶（PARP）中發現的特定識別序列。 該抑制劑被設計為甲酯以促進細胞滲透性。 （注意：如果預期的用途是純化或重組酶，應添加酯酶以產生游離羧基）。
| Alternate Name | Z-DEVD-FMK, Caspase-3 inhibitor, Z-DEVD fluoromethylketone |
| Peptide Sequence | Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK |
| Appearance | Liquid |
| Formulation | 1009-100 In DMSO (2 mM); 1009-20C In DMSO (10 mM) |
| Molecular Formula | C₃₀H₄₁FN₄O₁₂ |
| Molecular Weight | 668.7 |
| Purity | >98% by HPLC |
| SMILES | CC(C)C(C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CCC(=O)OC)NC(=O)C(CC(=O)OC)NC(=O)OCC1=CC=CC=C1 |
| InChi | InChI=1S/C30H41FN4O12/c1-17(2)26(29(42)33-20(22(36)15-31)13-24(38)45-4)35-27(40)19(11-12-23(37)44-3)32-28(41)21(14-25(39)46-5)34-30(43)47-16-18-9-7-6-8-10-18/h6-10,17,19-21,26H,11-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,43)(H,35,40)/t19-,20-,21-,26-/m0/s1 |
| InChi Key | GBJVAVGBSGRRKN-JYEBCORGSA-N |
| PubChem CID | 16760394 |
| Handling | Protect from light and moisture |