Z-DEVD-FMK肽抑制劑 | 貨號1009

Caspase-3 Inhibitor Z-DEVD-FMK

產品描述：Z-DEVD-FMK一種合成肽抑制劑，其不可逆地抑制半胱天冬酶-3和相關蛋白酶/半胱天冬酶活性並阻斷細胞凋亡。 DEVD是聚（ADP-核糖）聚合酶（PARP）中發現的特定識別序列。 該抑制劑被設計為甲酯以促進細胞滲透性。 （注意：如果預期的用途是純化或重組酶，應添加酯酶以產生游離羧基）。

Alternate Name	Z-DEVD-FMK, Caspase-3 inhibitor, Z-DEVD fluoromethylketone
Peptide Sequence	Z-Asp(OMe)-Glu(OMe)-Val-Asp(OMe)-FMK
Appearance	Liquid
Formulation	1009-100 In DMSO (2 mM); 1009-20C In DMSO (10 mM)
Molecular Formula	C₃₀H₄₁FN₄O₁₂
Molecular Weight	668.7
Purity	>98% by HPLC
SMILES	CC(C)C(C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CCC(=O)OC)NC(=O)C(CC(=O)OC)NC(=O)OCC1=CC=CC=C1
InChi	InChI=1S/C30H41FN4O12/c1-17(2)26(29(42)33-20(22(36)15-31)13-24(38)45-4)35-27(40)19(11-12-23(37)44-3)32-28(41)21(14-25(39)46-5)34-30(43)47-16-18-9-7-6-8-10-18/h6-10,17,19-21,26H,11-16H2,1-5H3,(H,32,41)(H,33,42)(H,34,43)(H,35,40)/t19-,20-,21-,26-/m0/s1
InChi Key	GBJVAVGBSGRRKN-JYEBCORGSA-N
PubChem CID	16760394
Handling	Protect from light and moisture