LILRB4重組蛋白| LILRB4/CD85k/ILT-3 Biovision貨號: P1187

| 代理廠牌: | ![]() |
| 原廠連結: | |
| 相關下載: |
特點
商品: Human CellExp™ LILRB4 / CD85k / ILT3, Cynomolgus Recombinant|貨號: P1187-10

產品介紹: 白細胞免疫球蛋白樣受體亞族B成員4(LILRB4)也稱為CD85抗原樣家族成員K(CD85K),免疫球蛋白樣轉錄物3(ILT-3),白細胞免疫球蛋白樣受體5(LIR-5) 單核細胞抑制性受體HM18屬於白細胞免疫球蛋白樣受體(LIR)家族。 LILRB4 / CD85K含有2個Ig樣的C2型(免疫球蛋白樣)結構域。 在單核細胞,巨噬細胞,樹突細胞,肺,自然殺傷細胞和B細胞中檢測到CD85K。 LILRB4 / CD85K是I類MHC抗原的受體。 CD85K識別HLA-A,HLA-B,HLA-C和HLA-G等位基因的廣譜,涉及免疫反應的下調和耐受性的發展。 LILRB4干擾TNFRSF5信號傳導和NF-κB上調,並抑制受體介導的細胞蛋白磷酸化和細胞內鈣離子的動員。
| Alternate Name | LILRB4, ILT3, LIR5, CD85K, HM18 |
| Gene Symbol | LILRB4 |
| Gene ID | 107128256 |
| Accession # | XP_015297198.1 |
| Source | HEK293 cells |
| Appearance | Lyophilized |
| Physical Form Description | Lyophilized from 0.22 μm filtered solution in PBS pH 7.4. Generally 5-8% Mannitol or Trehalose is added as a protectant before lyophilization. |
| Molecular Weight | 52.7 kDa |
| Purity by SDS-PAGE | > 85% |
| Endotoxin Level | < 1.0 EU per/μg |
| Biological Activity | Immobilized Human ANGPTL7, His Tag at 5 μg/mL (100 μL/well) can bind Cynomolgus LILRB4, Fc Tag with a linear range of 10-156 ng/mL. |
| Reconstitution Instructions | Reconstitute in sterile deionized water to the desired protein concentration. |
| Handling | Centrifuge the vial prior to opening. |
