BDNF 多株抗體 |貨號6725-100

產品介紹: Neurotrophins神經營養蛋白在發育過程中，扮演調節神經元自然發生的細胞死亡的作用。原型神經營養因子-神經生長因子（NGF），最初發現於20世紀50年代作為可溶性肽促進交感神經節的存活和神經突向外生長。鑑定三種另外的結構同源的神經營養因子；包括腦源性神經營養因子（BDNF）、神經營養因子-3（NT-3）、和神經營養蛋白-4（NT-4）（也稱為NT-5）。各種神經營養蛋白刺激不同，但部分重疊的神經元群體之體外存活。已經鑑定了神經營養因子通過其介導其活性的細胞表面受體。例如，Trk A受體是NGF的優先受體，但也結合NT-3和NT-4。 Trk B受體同樣地結合BDNF和NT-4，並且以較小的程度結合NT-3，而Trk C受體僅結合NT-3。

Size	100 μl
SKU+Size	6725-100
Antibody Target	BDNF
Alternate Name	BDNF; Brain-derived neurotrophic factor; Abrineurin
Host	Rabbit
Antibody Type	Polyclonal
Isotype	Rabbit IgG
Immunogen	This BDNF antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 206-236 amino acids from the C-terminal region of human BDNF.
Accession #	P23560
Gene ID	627
Appearance	Colorless liquid
Formulation	100 µl of antibody in PBS with 0.09% (W/V) sodium azide
Purification	This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Species Reactivity	Human
Application	Western blot, IHC
Positive Control	Western blot: CEM cell line, IHC: human brain tissue, FACS: CEM cells, IF: NCI-H460 cells
Application & Usage	Western blot: ~1:1000, IHC: ~1:10–1:50, IF: ~1:10–1:50, FC: ~1:10–1:50.