Irisin | Active, human recombinant 重組蛋白 | 貨號: 7852-50/7852-10

Activates beige fat cells

產品介紹: Irisin是最近發現的運動誘導的肌細胞，其由骨骼肌分泌並通過FNDC5的切割產生。 研究表明，Irisin刺激線粒體解偶聯蛋白-1（UCP-1;棕色脂肪的產熱能力的調節劑）表達，因此Irisin可以通過增加能量消耗來上調白色至棕色脂肪的轉化並改善全身代謝。因此，Irisin是一種潛在的新藥物靶標，用於研究代謝性疾病，如肥胖症和2型糖尿病（T2DM）。此外，FNDC5樣受體是保守的脊椎動物和關鍵的神經元發展。

Alternate Name	Fibronectin Type III Domain-containing Protein 5, FNDC5 (cleaved); Fibronectin Type III Repeat-containing Protein 2, FRCP2 (cleaved).
Gene Symbol	FNDC5
Gene ID	252995
Accession #	Q8NAU1
Source	E. coli
Appearance	Lyophilized powder
Physical Form Description	Lyophilized from PBS.
Molecular Weight	~13.00 kDa
Purity by SDS-PAGE	≥95%
Reconstitution Instructions	Reconstitute to 0.1 mg/ml with sterile water
Amino Acid Sequence	Full-length untagged Irisin (112 amino acids)
Handling	Centrifuge the vial prior to opening.
Storage Conditions	-20°C
Shipping Conditions	Gel Pack
USAGE	For Research Use Only! Not to be used in humans