抗癌劑 | 微血管抑制劑Nocodazole  貨號2185-50  | 50 mg

產品描述: Biovision提供一系列癌症相關分析套組；包括血管新生、細胞侵入Invasion、細胞遷移migration、抗癌劑、抗癌蛋白、癌症行為分析等分析商品。其中抗癌劑系列商品，具有高純度≥98% by HPLC且穩定的生化物質，可以使用在癌症相關的抑制劑和活化劑之研究實驗。Nocodazole微血管抑制劑(microtubule inhibitor)；抑制有絲分裂( inhibits mitosis)。通過結合於β-微管蛋白並防止形成兩個鏈間二硫鍵之一，從而抑制微管動力學，中斷有絲分裂紡錘體功能，高爾基複合體的碎片化。Nocodazole, A microtubule inhibitor; inhibits mitosis. Disrupts microtubules by binding to β‑tubulin and preventing formation of one of the two interchain disulfide linkages, thus inhibiting microtubule dynamics, disruption of mitotic spindle function, and fragmentation of the Golgi complex. Arrests the cell cycle at G2/M phase. Also inhibits autophagosome-lysosome fusion. Enhances homology-directed repair (HDR) efficiency and increases Cas9-mediated gene editing frequencies.

Alternate Name	5-(2-Thienylcarbonyl)-1H-benzimidazol-2-yl]carbonic acid, methyl ester
Appearance	Pale yelow solid
CAS #	31430-18-9
Molecular Formula	C₁₄H₁₁N₃O₃S
Molecular Weight	301.32
Purity	≥98% by HPLC
Solubility	DMSO (100 mM)
SMILES	COC(=O)NC1=NC2=C(N1)C=C(C=C2)C(=O)C3=CC=CS3
InChi	InChI=1S/C14H11N3O3S/c1-20-14(19)17-13-15-9-5-4-8(7-10(9)16-13)12(18)11-3-2-6-21-11/h2-7H,1H3,(H2,15,16,17,19)
InChi Key	KYRVNWMVYQXFEU-UHFFFAOYSA-N
PubChem CID	4122
MDL Number	MFCD00005588
Handling	Protect from air and light
Storage Conditions	-20°C
Shipping Conditions	Gel Pack

Nocodazole, A microtubule inhibitor; inhibits mitosis. Disrupts microtubules by binding to β‑tubulin and preventing formation of one of the two interchain disulfide linkages, thus inhibiting microtubule dynamics, disruption of mitotic spindle function, and fragmentation of the Golgi complex. Arrests the cell cycle at G2/M phase. Also inhibits autophagosome-lysosome fusion. Enhances homology-directed repair (HDR) efficiency and increases Cas9-mediated gene editing frequencies.

Catalog #	Product Name+	Size
1862-25	(R,S)-Lenalidomide	25 mg
1862-100	(R,S)-Lenalidomide	100 mg
2828-5	2′-Deoxy-6-thioguanosine	5 mg
2828-25	2′-Deoxy-6-thioguanosine	25 mg
2150-100	3,3′-Diindolylmethane	100 mg
2150-1000	3,3′-Diindolylmethane	1 g
2377-10	Amifostine	10 mg
2377-50	Amifostine	50 mg
2519-50	Artemisinin	50 mg
2519-250	Artemisinin	250 mg
1552-25	Betulinic acid	25 mg
1575-5	Bexarotene	5 mg
1575-50	Bexarotene	50 mg
2246-10	Bleomycin sulfate	10 mg
2246-50	Bleomycin sulfate	50 mg
1560-5	Brefeldin A	5 mg
B1140-5	Briciclib	5 mg
B1140-25	Briciclib	25 mg
1741-100	Capecitabine	100 mg
1741-1000	Capecitabine	1 g
1553-100	Carboplatin	100 mg
2075-5	Carnosic Acid	5 mg
2075-25	Carnosic Acid	25 mg
1550-100	Cisplatin	100 mg
1550-1000	Cisplatin	1 g
2236-5	Clofarabine	5 mg
2236-25	Clofarabine	25 mg
2239-10	Combretastatin A4	10 mg
2239-50	Combretastatin A4	50 mg
1815-5	CP-31398 Dihydrochloride	5 mg
1815-25	CP-31398 Dihydrochloride	25 mg
1578-5	Cyclopamine	5 mg
9657-1G	Cyclophosphamide monohydrate	1 g
9657-5G	Cyclophosphamide monohydrate	5 g
2833-5	Cytochlor	5 mg
2833-25	Cytochlor	25 mg
1524-500	Daunorubicin.HCl	500 mg
1524-10	Daunorubicin.HCl	10 mg
1524-50	Daunorubicin.HCl	50 mg
B1062-25	Diallyl trisulfide	25 mg
B1062-100	Diallyl trisulfide	100 mg
2232-10	Docetaxel	10 mg
2232-50	Docetaxel	50 mg
1527-5	Doxorubicin.HCl	5 mg
9579-5	Ellipticine	5 mg
9579-25	Ellipticine	25 mg
1970-50	Emetine dihydrochloride	50 mg
1970-250	Emetine dihydrochloride	250 mg
2012-1	Epothilone B	1 mg
2012-5	Epothilone B	5 mg
2231-1	Erastin	1 mg
2231-5	Erastin	5 mg
2896-10	Etoposide phosphate	10 mg
2896-50	Etoposide phosphate	50 mg
1746-5	EZSolution™ Rapamycin	5 mg
1763-10	Fludarabine Phosphate	10 mg
1763-50	Fludarabine Phosphate	50 mg
1564-1	Geldanamycin	1 mg
1759-25	Gemcitabine Hydrochloride	25 mg
1759-100	Gemcitabine Hydrochloride	100 mg
1533-10	Genistein	10 mg
2526-1	Hypericin	1 mg
2526-5	Hypericin	5 mg
2152-250	α-Galactosylceramide	250 µg
2152-1000	α-Galactosylceramide	1 mg
2722-50	α-Tocopheryl succinate	50 mg
2722-250	α-Tocopheryl succinate	250 mg
2038-100	Ilimaquinone	100 μg
2318-5	Imperatorin	5 mg
2318-25	Imperatorin	25 mg
9634-5	Iron Chelator, Dp44MT	5 mg
9634-25	Iron Chelator, Dp44MT	25 mg
1689-05	Jasplakinolide, jaspis johnstoni	50 µg
2408-100	L-Selenomethionine	100 mg
2408-500	L-Selenomethionine	500 mg
2408-1000	L-Selenomethionine	1 g
2181-100	Latrunculin A	100 µg
2182-1	Latrunculin B	1 mg
1885-50	Mitoxantrone	50 mg
1885-250	Mitoxantrone	250 mg
1772-250	Naringenin	250 mg
1772-1000	Naringenin	1 g
1576-5	Nedaplatin	5 mg
1891-5	Nimbolide	5 mg
1891-25	Nimbolide	25 mg
2185-10	Nocodazole	10 mg
2185-50	Nocodazole	50 mg
1730-25	Oridonin	25 mg
1730-5	Oridonin	5 mg
1577-25	Oxaliplatin	25 mg
1567-25	Paclitaxel	25 mg
2053-1	Pellitorine	1 mg
2053-5	Pellitorine	5 mg
1554-10	Pifithrin-ɑ	10 mg
1919-10	Piperlongumine	10 mg
1919-50	Piperlongumine	50 mg
1988-10	Piperlonguminine	10 mg
1988-50	Piperlonguminine	50 mg
1958-5	Pixantrone maleate	5 mg
1958-25	Pixantrone maleate	25 mg
2054-10	PK 11195	10 mg
2054-50	PK 11195	50 mg
2290-50	Plumbagin	50 mg
2290-250	Plumbagin	250 mg
2767-50	Podophyllotoxin	50 mg
2767-250	Podophyllotoxin	250 mg
2311-250	Prodigiosin	250 µg
2311-1000	Prodigiosin	1 mg
2073-5	Pterostilbene	5 mg
2073-25	Pterostilbene	25 mg
2436-5	Quinol 1h	5 mg
2436-25	Quinol 1h	25 mg
2437-5	Quinol 2	5 mg
2437-25	Quinol 2	25 mg
1568-5	Rapamycin	5 mg
1551-1000	Tamoxifen citrate	1 g
2226-10	Temozolomide	10 mg
2226-50	Temozolomide	50 mg
B1049-10	Toremifene citrate	10 mg
B1049-50	Toremifene citrate	50 mg
1959-5	Vinblastine Sulfate	5 mg
1959-25	Vinblastine Sulfate	25 mg
1957-5	Vinorelbine Tartrate	5 mg
1957-25	Vinorelbine Tartrate	25 mg
2694-5	VK3-OCH3	5 mg
2694-25	VK3-OCH3	25 mg
9693-5	Wogonin	5 mg
9693-25	Wogonin	25 mg

 

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