MCE (MedChem Express) -菸鹼醯胺 (Nicotinamide)

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菸鹼醯胺 (Nicotinamide)   | CAS#98-92-0 MCE貨號HY-B0150 

Nicotinamide is a form of vitamin B3 or niacin. Nicotinamide Hydrochloride inhibits SIRT2 activity (IC₅₀: 2 μM). Nicotinamide also inhibits SIRT1. Nicotinamide increases cellular NAD₊, ATP, ROS levels. Nicotinamide inhibits tumor growth and improves survival. Nicotinamide also has anti-HBV activity.

菸鹼醯胺(Nicotinamide)是維生素 B3 或菸鹼酸的一種形式。鹽酸菸鹼醯胺抑制 SIRT2 活性（IC50：2 μM）。菸鹼醯胺(Nicotinamide) 還能抑制 SIRT1。菸鹼醯胺(Nicotinamide) 可增加細胞 NAD+、ATP、ROS 水平。菸鹼醯胺(Nicotinamide) 可抑制腫瘤生長並提高存活率。菸鹼醯胺(Nicotinamide) 還具有抗B型肝炎病毒活性。

Molecular Weight	122.12
Formula	C6H6N2O
CAS No.	98-92-0
Appearance	Solid
Color	White to off-white
SMILES	O=C(C1=CC=CN=C1)N
Structure Classification	Alkaloids Pyridine Alkaloids
Initial Source	Endogenous metabolite Human Gut Microbiota Metabolites Microorganisms
Shipping	Room temperature in continental US; may vary elsewhere.

MedChemexpress (MCE) 產品類別－依研究類型區分：

•Anti-infection

•Antibody-drug Conjugate/ADC Related

•Apoptosis

•Autophagy

•Cell Cycle/DNA Damage

•Cytoskeleton

•Epigenetics

•GPCR/G Protein

•Immunology/Inflammation

•JAK/STAT Signaling•MAPK/ERK Pathway

•Membrane Transporter/Ion Channel

•Metabolic Enzyme/Protease

•Neuronal Signaling

•NF-κB

•PI3K/Akt/mTOR

•PROTAC

•Protein Tyrosine Kinase/RTK•Stem Cell/Wnt

•TGF-beta/Smad

•Vitamin D Related

•Others