鐵死亡Ferroptosis- Ferrostatin-1

Ferrostatin-1 (Fer-1)| CAS#347174-05-4 APExBIO貨號 A4371

Ferrostatin-1 is a selective inhibitor of ferroptosis.(Ferroptosis inhibitor, erastin-induced)

Ferrostatin-1 是鐵死亡的選擇性抑制劑。Ferrostatin-1 已被發現是一種有效的鐵死亡抑制劑(ferroptosis)。 Fer-1 可以透過阻斷胱胺酸輸入和穀胱甘肽產生來減弱氧化性、鐵依賴性癌細胞死亡(iron-dependent cancer cell death )。 據報道，它可以透過抑制脂質過氧化(lipid peroxidation)來防止亨廷頓病(Huntington’s disease)細胞模型死亡。[1]

Physical Appearance	A solid
Storage	Store at -20°C
M.Wt	262.35
Cas No.	347174-05-4
Formula	C15H22N2O2
Solubility	≥149 mg/mL in DMSO; ≥99.6 mg/mL in EtOH with ultrasonic; insoluble in H2O
SDF	Download SDF
Canonical SMILES	NC1=C(NC2CCCCC2)C=CC(C(OCC)=O)=C1
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	We do not recommend long-term storage for the solution, please use it up soon.

 

 

 

APExBIO台灣代理商

https://www.apexbt.com

APExBIO提供優質的胜肽和生物分析試劑，廣泛產品線如Protease、Chromatin/Epigenetics表觀遺傳學、MAPK Signal、DNA Damege/DNA repair、細胞凋亡、腫瘤生物學、Stem cell等研究領域， 還提供定制的服務，包括多肽合成，抗體的生產和檢測的發展。產品線DNA/RNA prep kit、Drug Screening panel、Bioactive peptides、Growth factors、Biotinylation Reagents、tag peptides、amino Acids、Growth factors等。APExBIO產品質量都伴隨著證書的分析，高效液相色譜，質譜，和HMNR數據。