Poly(I:C) Toll-like receptor 3 (TLR3) agonist CAS#24939-03-5 APExBIO貨號B5551

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Poly(I:C) Toll-like receptor 3 (TLR3) agonist CAS#24939-03-5 APExBIO貨號B5551
Poly(I:C) Toll-like receptor 3 (TLR3) agonist
產品介紹 Poly (I:C) 是一種合成的雙股 RNA (dsRNA) 類似物,是一種免疫刺激劑,可作為最有效的干擾素 (interferon, IFN) 誘導劑。 Toll 樣受體 3 (TLR3) 激動劑(agonist)[1]。其平均分子量在1.5-8kb之間。含有 TLR7/8 激動劑 R848 或 CL075 的混合物與 Poly (I:C) 結合,產生 3 天成熟的樹突細胞 [2]。通常用於刺激體內免疫系統的活化。也促進 hPSC 來源的心肌細胞的成熟[3]。
| Physical Appearance | A solid (HMW) |
| Storage | Store at -20°C |
| Cas No. | 24939-03-5 |
| Formula | (C10H13N4O8P)x.(C9H14N3O8P)x |
| Solubility | insoluble in DMSO; insoluble in EtOH; ≥21.5 mg/mL in H2O |
| Shipping Condition | Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice. |
| General tips | For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. We do not recommend long-term storage for the solution, please use it up soon. |

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