血管生成素-2 (Angiopoietin-2) Matched ELISA (Antibody Pair Set)  SinoBiological貨號SEK10691

Angiopoietin-2 Matched ELISA Antibody Pair Set,Human

AGPT2 Matched ELISA Antibody Pair Set, Human; ANG2 Matched ELISA Antibody Pair Set, Human; Angiopoietin-2 Matched ELISA Antibody Pair Set, Human

血管生成素-2（Angiopoietin-2, ANG 2 或 ANGPT2）是 ANG 家族(ANG family)的成員，在人類癌症的發生和生長過程中的血管生成(angiogenesis)中發揮著重要作用。 ANGPT-1 和 ANGPT-2 似乎都與酪氨酸激酶受體( tyrosine kinase receptor) Tie-2 結合，該受體主要存在於內皮細胞的管腔表面。 ANG-2 在血管生成( angiogenesis )中的作用通常被認為是 ANG1 的拮抗劑(antagonist)，抑制 ANG1 促進的 Tie2 信號傳導，而 Tie2 信號傳導對於血管成熟( blood vessel maturation)和穩定(stabilization)至關重要。 ANG-2 與另一種重要的血管生成因子血管內皮生長因子 A 協同調節血管生成。遺傳學研究表明，ANG-2 在發育過程中的淋巴管生成( lymphangiogenesis )中也至關重要。 ANG-2 具有調節血管張力( vascular tone)、激素分泌(hormone secretion)、組織生長( tissue growth)和神經活動( neural activity)的多種生理作用。一些報告表明，ANG-2可以在實驗系統中誘導新生血管形成(neovascularization)，這是由於不同生長因子的表達，如血管生成素2( angiopoietin 2)、血管內皮因子( vascular endothelial factor)及其受體、成纖維細胞生長因子( fibroblast growth factor)、血小板衍生生長因子( platelet derived growth factor)、轉化生長因子β(transforming growth factor beta )和表皮生長因素( epidermal growth factor)。此外，ANG-2血管生成素-2（Angiopoietin-2, ANG 2 或 ANGPT2）在許多腫瘤的脈管系統中強烈表達，並且有人認為ANG-2可能與其他細胞因子（例如血管內皮生長因子）協同作用，以促進腫瘤相關的血管生成和腫瘤進展。

產品介紹:  SinoBiological提供ELISA Antibody Pair Set系列商品；血管生成素-2 (Angiopoietin-2) ELISA Antibody Pair Set ，內含Capture Antibody、Detection Antibody、Standard。

Capture Antibody – 1 mg/mL of mouse anti-Human Angiopoietin-2 monoclonal antibody (in PBS, pH 7.4). Dilute to a working concentration of 2 μg/mL in PBS before coating. (Catalog: #10691-MM07)

Detection Antibody – 0.2 mg/mL of mouse anti-Human Angiopoietin-2 monoclonal antibody conjugated to horseradish-peroxidase (HRP) (in PBS, 50 % HRP-Protector, pH 7.4, store at 4℃). Dilute to working concentration of 0.5 μg/mL in detection antibody dilution buffer before use. (Catalog: # 10691-MM21)

Standard – Each vial contains 148 ng of recombinant Human Angiopoietin-2. Reconstitute with 1 mL detection antibody dilution buffer. After reconstitution, store at -20℃ to -80℃ in a manual defrost freezer. A seven-point standard curve using 2-fold serial dilutions in sample dilution buffer, and a high standard of 3500 pg/mL is recommended.

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Catalog #	Species	Molecule	Application
10084-R015	Human	CD274	ELISA, IHC-P
10004-R511	Human	ERBB2	ELISA, ELISA(Cap), FCM, lCC/IF, IF
10565-R102	Human	CD226	ELISA
10231-R301-P	Human	LDLR	FCM
10259-R110	Human	FCGR2B	WB, IHC-P, IP
10773-R023	Human	ASGR1	ELISA
10004-R002	Human	ERBB2	ELISA, IHC-P, FCM, ICC/IF, IF
10001-R021	Human	EGFR	WB, ELISA, ELISA(Det), ICC/IF, IF, IP
10694-R028	Human	EpCAM	WB, ELISA, ELISA(Det), IHC-P, FCM, ICC/IF, IF, IP
13909-R226	Human	F8	ELISA
10005-R017	Human	PVRL2	ELISA
10377-RD67	Human	PDCD1	ELISA, IHC-P
10594-RM03	Human	PCSK9	ELISA
10186-R125	Human	BSG	WB, ELISA, IHC-P, FCM, ICC/IF, IF, IP
10136-R111-P	Human	FLT1	FCM
10390-R024	Human	HAVCR2	ELISA, ELISA(Cap)
10390-R108	Human	HAVCR2	ELISA
11066-R105	Human	VEGFA	ELISA
11215-R107	Human	LAMP1	WB, ELISA, IHC-P, FCM, ICC/IF, IF, IP
11235-R019	Human	REG3A	ELISA, IHC-P
10973-R111	Human	vWF	ELISA, ELISA(Det), IHC-P
11050-R412	Human	NGF	ELISA
11279-R021	Human	CTNNB1	ELISA, IHC-P, ICC/IF, IF, IP
13908-R002	Human	ASGR2	ELISA, IHC-P, FCM, ICC/IF, IF
10008-R064	Human	VEGFA	ELlSA, ELISA(Det)
100087-R013	Human	FGF2	HC-P
10014-R101	Human	FGF2	ELISA
100393-R024-F	Human	GPC3	FCM
100393-R024-P	Human	GPC3	FCM
10084-R001	Human	CD274	ELISA
10231-R301-F	Human	LDLR	FCM
10289-R102	Human	LGALS3	HC-P
10400-R113	Human	CD4	EIISA, IHC-P
10417-R006	Human	TNFRSF1B	ELISA
10980-R081	Human	CD8A	HC-P
11051-Rn208	Human	HAVCR1	ELISA
12078-R001	Human	GLA	W8, ELISA, IP
10007-R104	Human	CSF3	ELISA
10073-R001	Human	CD14	IHC-P
10160-R005	Human	CFD	ELISA
10259-R112	Human	FCGR2B	ELISA.ELISA(Det)
10327-RM04	Human	MMP9	ELISA
10995-R018	Human	SerpinG1	WB, ELISA, ELISA(Det), IP
11031-R039	Human	CD8B	HC-P
11192-R179	Human	CD68	HC-P
11996-R351	Human	KIT	ELISA, IHC-P
12163-R005	Human	VSIG4	ELISA, ELISA(Det)
13908-R002-P	Human	ASGR2	FCM
100128-R001	Human	CD79A	IHC-P
100129-R101	Human	KRT14	WB, IHC-P, IP
100254-R211	Human	VIM	IHC-P