Human IgA lambda(dimer) |Nordic-MUbio貨號P 444

Background
純化的人 IgA1 λ (IgA1 lambda)可用作 IgA 參考抗原 (IgA reference antigen)、校準物(calibrator)、包被蛋白(coating protein)和封閉劑( blocking agent)，用於各種免疫測定(immunoassays)，包括免疫擴散(immunodiffusion)、免疫電泳(immunoelectrophoresis)、ELISA、蛋白質印跡(Western blotting)、斑點免疫結合測定 (dot-immunobinding assays, DIBA)、血細胞凝集(haemagglutination)和細胞結合測定( cell-binding assays)。

Product
Chromatographically purified Human IgA1 lambda, dimer. 0.5 ml solution of 1 mg/ml P 444. No preservative added. This IgA1 consists mainly of dimers (as shown in non-reducing PAGE) and may contain traces of J chain. Confirmed by immunoelectrophoresis and double radial immunodiffusion (Ouchterlony). Not less than 98% as determined by agar-gel electrophoresis.

Concentration: 1 mg/ml

Storage
After arrival store at +4°C. Prolonged storage may be at -20°C. Allow to stand at ambient temperature for 5-10 minutes to reach equilibrium. Working dilutions may be prepared by adding the required amount of phosphate buffered saline (PBS), should not be refrozen and preferably used within 24 hours. Repeated thawing and freezing should be avoided. If a slight precipitation occurs upon storage, this should be removed by centrifugation and will not affect the performance of the product.

Shipping Conditions: This product is shipped at ambient temperature.

Caution
This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Exalpha Biologicals accepts no liability for any inaccuracies or omissions in this information.

References
Hansen IS, Hoepel W, Zaat SAJ, Baeten DLP, den Dunnen J. Serum IgA Immune Complexes Promote Proinflammatory Cytokine Production by Human Macrophages, Monocytes, and Kupffer Cells through FcαRI-TLR Cross-Talk. J Immunol. 2017;199(12):4124-4131. doi:10.4049/jimmunol.1700883