GLUT4抗體 | 貨號3945-30T

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GLUT4 Antibody
產品描述:Insulin stimulates glucose uptake in the muscles and adipose tissues by activating GLUT4 (Glucose Transporter Type 4). GLUT 4 is a transmembrane protein that facilitates glucose transport from storage sites to cell surface. Human insulin resistance involves a defect in GLUT4 that leads to accumulation in a dense membrane compartment from which insulin is unable to recruit GLUT4 to the cell surface。胰島素(Insulin)通過激活GLUT4(4型葡萄糖轉運蛋白)刺激肌肉(muscles)和脂肪組織(adipose tissues)吸收葡萄糖(glucose)。 GLUT 4是一種跨膜蛋白(transmembrane protein),可促進葡萄糖(glucose)從存儲位點(storage sites)轉運到細胞表面(cell surface)。 人胰島素抵抗涉及GLUT4的缺陷,該缺陷導致在緻密膜室中積累(accumulation),胰島素無法從該膜室將GLUT4募集到細胞表面。

| Antibody Target | GLUT4 |
| Alternate Name | Solute carrier family 2, facilitated glucose transporter member 4, Glucose transporter type 4, insulin-responsive, GLUT-4 |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Synthetic peptide surrounding amino acid 403 of mouse GLUT4. |
| Accession # | EDL12495.1 |
| Gene ID | 20528 |
| Appearance | Colorless liquid |
| Concentration | 0.5 mg/ml |
| Formulation | 200 µg (0.5 mg/ml) affinity purified rabbit anti-GLUT4 polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal |
| Purification | Affinity purified |
| Species Reactivity | Mouse, rat |
| Application | Western blot |
| Positive Control | 3T3 cell lysate, rat kidney tissue lysate |
| Application & Usage | Western blot analysis (1-4 µg/ml). However, the optimal conditions should be determined individually. 3T3 cell lysate can be used as a positive control. |
| Handling | The antibody solution should be gently mixed before use. |
乾浴加熱水浴槽 | Finnpipette F3 微量分注器 | 試管振盪器 Vortex Mixer | Genereach迷你型微量離心機 | ELISA儀器
