E蛋白DIII（C-C’）的重組單株抗體| Anti-E-protein DIII (C-C’) [ZV-48]  貨號Ab000810-2.0   

Recombinant monoclonal antibody to E-protein DIII (C-C’). Manufactured using AbAb’s Recombinant Platform with variable regions (i.e. specificity) from the hybridoma ZV-48.

抗體介紹:  E蛋白DIII（C-C’）的重組單株抗體 (Clone Name: ZV-48) 。其免疫原為分別通過在感染ZIKV H / PF / 2013的30天後，分別用1000 FFU的ZIKV MR-766感染小鼠，然後在30天內加強免疫，並用活ZIKV DIII進行最終的靜脈內加強免疫（第299-407位氨基酸） ZIKV E蛋白）。特異性：ZV-48在結構域III（DIII，CC-C’環）上與寨卡病毒包膜蛋白(Zika virus envelope protein)結合。 與其他測試的黃病毒(flaviviruses)沒有交叉反應的報導。Published Application(s): crystallization, NTRL, SPR, FC。Published Species Reactivity: Zika Virus

Alternative Name(s) of Target:  Envelope protein; ZIKV E; ZV48

免疫原(Immunogen: 通過用鼠重組TIGIT四聚體免疫TIGIT  –  /  – 小鼠來產生該抗體。Clone Name: 1B4。Published Application(s): Blocking, ELISA, FC

Published Species Reactivity: Mouse

Antibody first published in: Zhao et al. Structural Basis of Zika Virus-Specific Antibody Protection. Cell. 2016 Aug 11;166(4):1016-27 PMID:27475895