人重組α-烯醇酶 | Human Recombinant Alpha-Enolase貨號6363-100

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Human Recombinant Alpha-Enolase人重組α-烯醇酶 | 貨號6363-100
A metalloenzyme responsible for conversion of 2-PG to PEP


產品描述:α-烯醇酶(Alpha-enolase),也稱為烯醇酶1(Enolase 1),是三種烯醇化酶同工酶 (enolase isoenzymes) 之一,是在大多數組織中表達的糖酵解酶(glycolytic enzyme)。 該蛋白質在缺氧條件(hypoxic conditions)下在無氧代謝(anaerobic metabolism)中起關鍵作用,並且可以在組織侵入(tissue invasion)期間充當細胞表面纖溶酶原受體(cell surface plasminogen receptor)。 在一些乳腺癌(breast)和肺癌(lung cancer)病例中,α-烯醇酶(alpha-enolase)的異常表達與腫瘤進展相關。 它也被鑑定為與橋本氏腦病(Hashimoto’s encephalopathy)和嚴重哮喘(severe asthma)相關的自身抗原(auto antigen)。

| Alternate Name | Non-Neuronal Enolase (NNE); Enolase-1(ENO1); MBP-1; MYC promoter-binding protein 1; PPH; taucrystallin. |
| Gene Symbol | ENO1 |
| Gene ID | 2023 |
| Accession # | P06733 |
| Source | E. Coli |
| Appearance | Liquid |
| Physical Form Description | In 50 mM Tris, 150 mM NaCl, 20 mM MgCl2 and 20% Glycerol |
| Molecular Weight | 47.1 kDa (1-434 aa) |
| Purity by SDS-PAGE | ≥90% |
| Biological Activity | ≥ 80 U/mg |
| Handling | Centrifuge the vial prior to opening. |
| Storage Conditions | -20°C |
乾浴加熱水浴槽 | Finnpipette F3 微量分注器 | 試管振盪器 Vortex Mixer | Genereach迷你型微量離心機 | ELISA儀器
