Mouse Anti-Influenza A, Nucleoprotein-HRP抗體 | 貨號10780-05

小鼠抗流感病毒A核蛋白介紹:  A型流感病毒核蛋白(Influenza virus type A nucleoprotein)，也稱為NP，由498個氨基酸序列組成，在流感病毒中是特定類型的。 NP包封病毒基因組 (NP encapsulates) 以形成核糖核蛋白（RNP）顆粒，用於轉錄(transcription)和包裝(packaging)。 特異性識別A型流感病毒NP。 該克隆可以與克隆FluA-NP 2C9（SBA貨號#10770-01）配對作ELISA的檢測抗體。

小鼠抗流感病毒A核蛋白抗體特性: Mouse Anti-Influenza A, Nucleoprotein-UNLB抗體。免疫源為Recombinant influenza vrus type A nucleoprotein。抗體專一性為Influenza virus type A nucleoprotein。抗體溶液Borate buffered saline, pH 8.2。

Recombinant influenza proteins were resolved by electrophoresis, transferred to PVDF membrane, and probed with Mouse Anti-Influenza A, Nucleoprotein-UNLB (SB Cat. No. 10780-01). Proteins were visualized using Goat Anti-Mouse IgG, Human ads-HRP (SB Cat. No. 1030-05) and chemiluminescent detection.

Clone	FluA-NP 4F1
Isotype	Mouse (BALB/c) IgG1κ
Isotype Control	Mouse IgG1-HRP
Immunogen	Recombinant influenza virus type A nucleoprotein
Specificity	Influenza virus type A nucleoprotein
Alternalte Name(s)	NP
Description	Influenza virus type A nucleoprotein, also known as NP, is composed of a 498 amino acid sequence and is type-specific in influenza viruses. The NP encapsulates the virus genome to form a ribonucleoprotein (RNP) particle for the purposes of transcription and packaging. The monoclonal antibody FluA-NP 4F1 has been shown to specifically recognize type A influenza virus NP in virus infected cell culture and patient samples. This clone can be paired as a detection antibody for ELISA with clone FluA-NP 2C9 (SB Cat. No. 10770-01).
Format/Conjugate	HRP (Horseradish Peroxidase)
Buffer Formulation	50% Glycerol/50% Phosphate buffered saline, pH 7.4
Volume	1.0 mL
Storage & Handling	2-8°C Please refer to product specific SDS
Applications	Applications for relevant formats of this clone include – ELISA – Quality tested Immunocytochemistry – Reported in literature 1-4,6,7 Western Blot – Reported in literature 2,4,5
Recommended Dilutions	Please refer to product specific Technical Bulletin

 

Cat. No.	Product Description	Clone	Size
10730-05	Mouse Anti-Influenza A, Matrix Protein-HRP	FluAc	1.0 mL
10730-01	Mouse Anti-Influenza A, Matrix Protein-UNLB	FluAc	0.1 mg
10770-01	Mouse Anti-Influenza A, Nucleoprotein-UNLB	FluA-NP 2C9	0.5 mg
10780-05	Mouse Anti-Influenza A, Nucleoprotein-HRP	FluA-NP 4F1	1.0 mL
10780-01	Mouse Anti-Influenza A, Nucleoprotein-UNLB	FluA-NP 4F1	0.5 mg
10885-05	Mouse Anti-Influenza B, Nucleoprotein-HRP	3D7	1.0 mL
10885-01	Mouse Anti-Influenza B, Nucleoprotein-UNLB	3D7	0.5 mg
10890-05	Mouse Anti-Influenza B, Nucleoprotein-HRP	1H7a	1.0 mL
10890-01	Mouse Anti-Influenza B, Nucleoprotein-UNLB	1H7a	0.5 mg

文獻參考

References

1. Wei G, Meng W, Guo H, Pan W, Liu J, Peng T, et al. Potent neutralization of influenza A virus by a single-domain antibody blocking M2 ion channel protein. PLoS One. 2011;6(12):e28309. (ICC)
2. Shoji M, Takahashi E, Hatakeyama D, Iwai Y, Morita Y, Shirayama R, et al. Anti-influenza activity of C60 fullerene derivatives. PLoS One. 2013;8(6):e66337. (ICC, WB)
3. Hatakeyama D, Shoji M, Yamayoshi S, Hirota T, Nagae M, Yanagisawa S, et al. A novel functional site in the PB2 subunit of influenza A virus essential for acetyl-CoA interaction, RNA polymerase activity, and viral replication. J Biol Chem. 2014;289:24980-94. (ICC)
4. Shoji M, Arakaki Y, Esumi T, Kohnomi S, Yamamoto C, Suzuki Y, et al. Bakuchiol is a phenolic isoprenoid with novel enantiomer-selective anti-influenza A virus activity involving Nrf2 activation. J Biol Chem. 2015 Oct 7. pii: jbc.M115.669465. [Epub ahead of print]. (ICC, WB)
5. Narkpuk J, Wanitchang A, Kramyu J, Frantz PN, Jongkaewwattana A, Teeravechyan S. An unconventional BST-2 function: down-regulation of transient protein expression. Biochem Biophys Res Commun. 2014;450:1469-74. (WB)
6. Farooqui A, Leon AJ, Lei Y, Wang P, Huang J, Tenorio R, et al. Heterogeneous virulence of pandemic 2009 influenza H1N1 virus in mice. Virol J. 2012;9:104. (ICC)
7. Shoji M, Woo S, Masuda A, Win NN, Ngwe H, Takahashi E, et al. Anti-influenza virus activity of extracts from the stems of Jatropha multifida Linn. collected in Myanmar. BMC Complement Altern Med. 2017;17:96. (ICC)