BioSim™Bevacizumab ELISA試劑盒 | 貨號E4373-100 合併為Abcam ab237642

BioSim™ Bevacizumab (Avastin®) (Human) ELISA Kit.

產品描述：Bevacizumab（Avastin®）是一種特異於所有人血管內皮生長因子-A（VEGF-A）同種型的重組人IgG1單克隆抗體。人源化抗VEGF單克隆抗體Bevacizumab已被FDA批准作為轉移性結直腸癌與化療聯合的一線治療。Bevacizumab在幾個物種中的藥代動力學特性，並且與典型的人源化單克隆抗體一致。文獻顯示，維持治療期間循環濃度的監測代表了一些其他副作用的直接和/或間接因素。鑑定（非）應答的生物標誌物和可能與血清濃度有關的不良藥物反應的風險因素和維持Bevacizumab的有效濃度以便用可靠的方法潛在地避免一些副作用可能是有益的。 BioVision的BioSim™Bevacizumab ELISA試劑盒用於特異性定量人血清或血漿中Bevacizumab的濃度，具有高靈敏度和重現性。

貝伐珠單抗標準曲線範例
典型標準曲線：此標準曲線僅用於演示。每次測定都必須運行標準曲線。

Cat # +Size	E4373-100 (ab237642)
Size	100 assays
Kit Summary	• Detection method- Absorbance (450 nm) • Species reactivity- Human • Application- quantitative measurement of Bevacizumab in human serum and plasma
Detection Method	Absorbance (450 nm)
Species Reactivity	Human
Applications	This ELISA kit is used for quantitative measurement of Bevacizumab in human serum and plasma
Features & Benefits	• Easy, convenient, sensitive and time-saving method to measure the level of Bevacizumab in human serum and plasma. • Detection Range: 30 – 1000 ng/ml • Sensitivity: 30 ng/ml • Assay Precision: Intra-Assay: CV < 15%; Inter-Assay: CV < 15% (CV (%) = SD/mean X 100) • Recovery rate: 85 – 115% with normal human serum samples with known concentrations • Cross Reactivity: No significant cross-reactivity or interference with other proteins present in native human serum or other therapeutic immunoglobulins.
Kit Components	• Micro ELISA Plate • Bevacizumab Standards (S1 – S7) • Assay Buffer • HRP-conjugate Probe • TMB substrate (Avoid light) • Stop Solution • Wash buffer (20X) • Plate sealers