Smad1 Antibody抗體｜BIOVISION貨號3461
| 代理廠牌： |  |
| 原廠連結： | |
| 相關下載： |
特點
產品介紹: Smad蛋白是果蠅母親對dpp（Mad）的哺乳動物同源物，已被認為是TGFβ/ BMP信號傳導的下游效應物。 Smad1，Smad5和Smad8是BMP2和BMP4功能的效應子，而Smad2和Smad3參與TGF-β和激活素介導的生長調節。 已顯示Smad4通過與各種Smad家族成員的相互作用來介導所有上述活動。 Smad6和Smad7通過乾擾TGFβ介導的其他Smad家族成員的磷酸化來調節對激活素/TGFβ信號傳導的反應。
| Antibody Target | Smad1 |
| Host | Rabbit |
| Antibody Type | Polyclonal |
| Isotype | Rabbit IgG |
| Immunogen | Synthetic peptide corresponding to amino acid residues around 253 of human Smad1 |
| Accession # | P97588 |
| Gene ID | 25671 |
| Appearance | Colorless liquid |
| Concentration | 0.5 mg/ml |
| Formulation | 100 µg (0.5 mg/ml) affinity purified rabbit polyclonal antibody in phosphate-buffered saline (PBS) containing 30% glycerol, 0.5% BSA, and 0.01% thimerosal. |
| Purification | Affinity purified |
| Species Reactivity | Human |
| Application | Western blot |
| Application & Usage | Western blotting (0.5-4 µg/ml). However, the optimal concentrations should be determined individually. The antibody recognizes ~50-60 kDa Smad1 from samples of human, mouse, and rat origins. Reactivity to other species has not been tested. |
| Handling | The antibody solution should be gently mixed before use. |
| Storage Conditions | -20 °C |
| Shipping Conditions | Gel Pack |
| USAGE | For Research Use Only! Not For Use in Humans. |