瘦蛋白抗體 Leptin Antibody | 貨號5367-100

 

產品描述：瘦蛋白是小鼠肥胖基因最近鑑定的蛋白質產物。 肥胖基因中具有突變的小鼠阻斷瘦素的合成已經被發現是肥胖的和糖尿病的，並具有降低的活性，代謝和體溫。 已經從人類，猿猴，小鼠和大鼠細胞中分離出編碼瘦蛋白的cDNA克隆。 人瘦蛋白與小鼠蛋白質共享約84％的序列同一性。 人瘦蛋白cDNA編碼167個氨基酸殘基的蛋白質，具有21個氨基酸殘基的信號序列，被切割產生146個氨基酸殘基的成熟蛋白質。 瘦素mRNA的表達已被證明限於脂肪組織。 瘦素在生殖，免疫反應和神經內分泌信號傳導中起重要作用。

Antibody Target	Leptin
Alternate Name	Leptin Polyclonal, Anti-Leptin antibody, Leptin antibody, Anti- Leptin, Leptin
Host	Rabbit
Antibody Type	Polyclonal
Isotype	Rabbit IgG
Immunogen	E. coli-expressed recombinant mouse Leptin
Accession #	NP_032519
Gene ID	16846
Appearance	Colorless liquid
Concentration	0.5 mg/ml
Formulation	30 µg (0.5 mg/ml) affinity purified rabbit anti-mouse Leptin polyclonal antibody in phosphate buffered saline (PBS), pH 7.2, containing 30% glycerol, 0.5% BSA, 0.01% thimerosal.
Purification	Affinity purified
Species Reactivity	Mouse
Application	Western blot
Application & Usage	Western blot analysis (0.5-2 µg/ml). However, the optimal conditions should be determined individually. Other applications have not been tested.