Aprotinin | An inhibitor of trypsin and related proteolytic enzymes貨號4690

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特點
An inhibitor of trypsin and related proteolytic enzymes
產品描述:抑肽酶抑制幾種蛋白水解酶如胰凝乳蛋白酶,激肽釋放酶,纖溶酶和胰蛋白酶的活性。它存在於血液和大多數組織中,在肺中濃度很高,抑制促炎細胞因子的釋放並維持糖蛋白體內平衡。在血小板中,抑肽酶減少糖蛋白損失(例如GpIb,GpIIb / IIIa),而在粒細胞中則抑制促炎粘著糖蛋白的表達。 抑肽酶是一種天然的蛋白酶抑制劑多肽,由排列在單個多肽鏈中的58個氨基酸組成,由三個二硫鍵交聯,分子量為6512道爾頓。 抑肽酶通過專有的色譜技術進行純化。
| Alternate Name | Pancreatic trypsin inhibitor, Basic protease inhibitor, BPI, BPTI, Aprotinin, AP |
| Source | Bovine lung |
| Appearance | Lyophilized protein |
| Physical Form Description | Sterile filtered and lyophilized with no additives |
| Molecular Weight | 6.5 kDa |
| Purity by SDS-PAGE | ≥98% |
| Purity by | ≥98% |
| Endotoxin Level | <0.1 ng/μg |
| Biological Activity | 5 x 10⁶ IU/mg. |
| Reconstitution Instructions | Reconstitute in H₂O to a concentration of 1 mg/ml. The solution can then be diluted into other aqueous buffers and store at 4°C for 1 week or –20°C for future use. For long-term storage, it is recommend to add a carrier protein (e.g., 0.1% BSA). Prevent f |
| Handling | Centrifuge the vial prior to opening. |
