抗α5β1整合素（Volociximab）人IgG4抗體 | 貨號A1092-200

Anti-alpha 5 beta 1 Integrin (Volociximab), Human IgG4 Antibody

BioVision的研究級生物仿製藥。基於人IgG的單克隆抗體（mAb）是癌症治療中增長最快的類別。 幾種單克隆抗體已被FDA批准用於治療各種solid tumors實體瘤和hematological malignancies血液惡性腫瘤。 BioVision提供人IgG型式之的research grade biosimilars 研究級生物仿製藥以供應研究需求。 單克隆抗體使用具有來自治療性抗體的可變區的重組技術製造，以實現相似的安全性和功效。 這些抗體可用作臨床前鑑定之對照和用於開發新型治療劑之效力測定。主要特徵：無添加劑：在含有防腐劑的PBS緩衝液（0.02％Proclin 300）; 高純度：使用蛋白A> 98％純度; 多功能：可用於各種應用; ELISA，Neutralization，流式細胞術，IHC，IF

Immunofluorescent and Immunohistochemical staining using anti-Carcinoembryonic antigen (Arcitumomab), Human IgG1 Antibody (Cat. No. A1096-200) (A & B) and Anti-CD52 (Campath-1H), Human IgG1 Antibody (Cat. No. A1105-200) (C & D).

Volociximab產品介紹: Volociximab該抗體與a5ß1 integrin特異性結合，該蛋白是配體如fibronectin纖連蛋白，vitronectin玻連蛋白，laminins層粘連蛋白和collagens膠原之糖蛋白跨膜受體超家族的一部分。 a5ß1整合素受體在細胞過程如inflammation炎症，cell proliferation細胞增殖，angiogenesis血管生成和tumour metastasis腫瘤轉移中扮演關鍵作用。原始小鼠抗體的可變結構域，嵌合小鼠：該抗體的人IgG4版本已經在體內測試：在具有激光誘導的脈絡膜新血管形成（CNV）的cynomolgus monkeys食蟹猴中，在兔模型和人類志願者中。 該抗體用PDL Biopharma和Biogen-Idec達到II期臨床試驗。

更多抗體 抗CD20（利妥昔單抗） | 抗α5β1整合素（Volociximab） | Anti-HER2 (Trastuzumab) | 抗VEGF（Bevacizumab） | 抗EGFR（西妥昔單抗）嵌合抗體  | 抗CD11a（Efalizumab)） | Anti-PD-L1 (Atezolizumab) 

Cat # +Size	A1092-200
Size	200 µg
Antibody Target	ITGA5
Alternate Name	Fibronectin receptor; CD49 antigen-like family member E; Integrin alpha-F; VLA-5; CD49e
Host	Recombinant
Antibody Type	Monoclonal
Isotype	Human IgG4, kappa
Immunogen	Heterodimeric α5β1Fc fusion protein
Accession #	P08648
Gene ID	3678
Appearance	Colorless liquid
Formulation	200 µg affinity purified human antibody in phosphate-buffered saline (PBS) containing 0.02% Proclin 300
Purification	Affinity purified using protein A
Species Reactivity	Human
Application	ELISA; FC; IF; Block; IHC
Handling	The antibody solution should be gently mixed before use

 

Cat. No.	Product Name	Trade Name	Isotype	Size
A1045-100	Anti-VEGF (Bevacizumab), humanized Antibody	Avastin	Human IgG1	100 µg
A1046-100	Anti-HER2 (Trastuzumab), humanized Antibody	Herceptin	Human IgG1	100 µg
A1047-100	Anti-EGFR (Cetuximab), Chimeric Antibody	Erbitux	Human IgG1	100 µg
A1048-100	Anti-TNF-α (Adalimumab), humanized Antibody	Humira	Human IgG1	100 µg
A1049-100	Anti-CD20 (Rituximab), Chimeric Antibody	Mabthera	Human IgG1	100 µg
A1050-100	Anti-EGFR (Panitumumab), humanized Antibody	Vectibix	Human IgG1	100 µg
A1088-200	Anti-OX40L (Oxelumab), Human IgG1 Antibody	Xolair	Human IgG1	200 µg
A1089-200	Anti-CD11a (Efalizumab), Human IgG1 Antibody	Raptiva	Human IgG1	200 µg
A1090-200	Anti-EGFR (Matuzumab), Human IgG1 Antibody	Matuzumab	Human IgG1	200 µg
A1091-200	Anti-CD4 (Clenoliximab), Human IgG4 Antibody	Clenoliximab	Human IgG4	200 µg
A1092-200	Anti-alpha 5 beta 1 Integrin (Volociximab), Human IgG4 Antibody	Volociximab	Human IgG4	200 µg
A1093-200	Anti-TNF alpha (Humicade), Human IgG4 Antibody	Humicade	Human IgG4	200 µg
A1094-200	Anti-CD40L (Ruplizumab), Human IgG1 Antibody	Antova	Human IgG1	200 µg
A1096-200	Anti-Carcinoembryonic antigen (Arcitumomab), Human IgG1 Antibody	CEA-Scan	Human IgG1	200 µg
A1097-200	Anti-TNF alpha (Infliximab), Human IgG1 Antibody	Remicade	Human IgG1	200 µg
A1098-200	Anti-IL-2R alpha (CD25) (Basiliximab), Human IgG1 Antibody	Simulect	Human IgG1	200 µg
A1099-200	Anti-IL-2R alpha (Daclizumab), Human IgG1 Antibody	Zenapax	Human IgG1	200 µg
A1105-200	Anti-CD52 (Campath-1H), Human IgG1 Antibody	Campath	Human IgG1	200 µg
A1305-100	Anti-PD-L1 (Atezolizumab), Humanized Antibody	Tecentriq	Human IgG1	100 µg
A1306-100	Anti-PD-1 (Pembrolizumab), Humanized Antibody	Keytruda	Human IgG1	100 µg
A1307-100	Anti-PD-1 (Nivolumab), Humanized Antibody	Opdivo	Human IgG1	100 µg

蛋白質定量商品 Coomassie blue蛋白質定量分析套組 | BCA蛋白測定試劑盒(低濃度10-600ug/ml)| 5％耐洗滌 | BCA蛋白測定試劑盒 (還原劑兼容)