Stat3 Inhibitor I, S3I-201抑制劑   | 貨號1775-25   5MG-25MG包裝

產品介紹: S3I-201在體外抑制Stat3.Stat3複合物形成和Stat3-DNA結合活性（IC 50 = 86±33μM）和Stat3依賴性轉錄活性。 S3I-201抑制Stat3調控的編碼細胞週期蛋白D1，Bcl-xL和存活蛋白的基因的表達，並抑制人體乳腺腫瘤的生長。

分子型式C₁₆H₁₅NO₇S | 分子量Molecular Weight: 365.36 | 純度Purity: ≥: 97.74%

Alternate Name	2-Hydroxy-4-[[[[4-methylphenyl)sulfonyl]oxy]acetyl]amino]-benzoic acid; NSC 74859; S3I-201
Appearance	Off-white solid
CAS #	501919-59-1
Molecular Formula	C₁₆H₁₅NO₇S
Molecular Weight	365.36
Purity	≥97% by HPLC
Solubility	DMSO (10 mg/ml)
SMILES	CC1=CC=C(C=C1)S(=O)(=O)OCC(=O)NC2=CC(=C(C=C2)C(=O)O)O
InChi	InChI=1S/C16H15NO7S/c1-10-2-5-12(6-3-10)25(22,23)24-9-15(19)17-11-4-7-13(16(20)21)14(18)8-11/h2-8,18H,9H2,1H3,(H,17,19)(H,20,21)
InChi Key	HWNUSGNZBAISFM-UHFFFAOYSA-N
PubChem CID	252682
MDL Number	MFCD09907564