Leptin, murine recombinant    4367-5包裝5MG

Adipose-derived hormone which regulates energy intake & energy expenditure

產品介紹: 瘦蛋白（抗肥胖蛋白）是小鼠ob（肥胖）基因的蛋白質產物，似乎涉及食慾控制。 ob基因在脂肪組織中表達，被認為是調節身體脂肪儲存。 具有ob / ob基因型的小鼠也形成類似II型（非胰島素依賴型）糖尿病的糖尿病形式。 鼠瘦蛋白是含有147個氨基酸殘基的16kDa蛋白質。

Alternate Name	OB Protein, Obesity Protein, OBS, Obesity factor.
Gene Symbol	LEP
Gene ID	16846
Accession #	P41160
Source	E. coli
Appearance	Lyophilized protein
Physical Form Description	Lyophilized with no additives
Molecular Weight	16.2 kDa
Purity by SDS-PAGE	≥98%
Endotoxin Level	<0.1 ng/μg
Biological Activity	Determined in an in vivo assay using the ob/ob mouse obesity model and NZO. Both strains of mice were treated via intraperitoneal injection once daily at a dose of 5 µg leptin/gm of body weight for 7 days. Significant effects on body weight, food consump
Reconstitution Instructions	Reconstitute in 10 mM HCl to a concentration of 1 mg/ml. The solution can then be diluted into other aqueous buffers and stored at 4°C for 1 week or –20°C for future use.