【SARS-CoV-2 / COVID-19抗體】IgM/IgG抗體中和測定neutralization assays /血清學對照
【SARS-CoV-2 / COVID-19抗體】- 抗體中和測定 (neutralization assays) /血清學對照 (serological controls)
Absolute antibody 提供一系列可識別SARS-CoV-2（也稱為2019-nCoV或COVID-19）的抗冠狀病毒抗體。抗SARS單株抗體CR3022於2006年首次描述，並在2020年初，研究人員 (researchers showed) 表明該單株抗體與當時的2019-nCoV具有高親和力，可應用於crystallography, NTRL, SPR, ELISA試驗。Absolute antibody 提供33種不同之COVID-19抗體 (available in our catalog )，一系列人類 IgG1、 IgG1 Fc Silent、 IgG2、 IgG3、IgM、 IgA、Fab、 Fab2 抗體，可用於中和測定(neutralization assays) 和血清學對照 (serological controls)。兔 IgG，小鼠 IgG2b和小鼠 IgM用於檢測應用，共標記研究(co-labelling studies )和動物模型研究( animal model research)。具有His標籤的人和小鼠Fab和Fab2抗體，用於需要抗體片段(antibody fragments)的應用以及位點特異性功能化 (site-specific functionalization)。專有的人IgG1和小鼠IgG2b Fc Silent™ formats，旨在識別Fc依賴性和Fc依賴性效應子功能，並促進對抗體依賴性增強（ADE）作用的研究。
Available anti-COVID-19 antibody formats in our reagent catalog now include:
- Human IgG1, IgG2, IgG3, IgA and IgM for use in neutralization assays and as serological controls
- Rabbit IgG, mouse IgG2b and mouse IgM for detection applications, co-labelling studies and animal model research
- Human and mouse Fab and Fab2 formats with His-tags, for applications where antibody fragments are desirable and for site-specific functionalization
- Our proprietary human IgG1 and mouse IgG2b Fc Silent™ formats, which are aimed at discerning Fc-dependent and Fc-independent effector functions and facilitating research into the role of antibody-dependent enhancement (ADE)
| Format | Catalog Number |
| Human IgG1 | Ab01680-10.0 |
| Human IgG1 Fc Silent™ | Ab01680-10.3 |
| Human IgG2 | Ab01680-11.0 |
| Human IgG3 | Ab01680-12.1 |
| Human IgM | Ab01680-15.0 |
| Human IgA | Ab01680-16.0 |
| Human Fab | Ab01680-10.6 |
| Human Fab2 | Ab01680-10.7 |
| Rabbit IgG | Ab01680-23.0 |
| Mouse IgG2b | Ab01680-3.0 |
| Mouse IgG2b Fc Silent™ | Ab01680-3.3 |
| Mouse IgM | Ab01680-21.0 |
| Mouse Fab | Ab01680-1.6 |
| Mouse Fab2 | Ab01680-1.7 |
| Clone Name | Available Formats | Applications |
|---|---|---|
| Anti-Spike Protein [CV1] | Human IgG1, IgM, IgA, IgA1, IgA2, IgG2, IgG3, Fab fragment and Fab 2; Mouse IgG1, IgM, Fab fragment and Fab2; Rabbit IgG; Cat IgG1 and IgM; Ferret IgG1, IgM and IgA | NTRL, ELISA, FC, Therapeutic |
| Anti-Spike Protein (RBD) [CV30] | Human IgG1, IgM, IgA, IgA1, IgA2, IgG2, IgG3, Fab fragment and Fab 2; Mouse IgG1, IgM, Fab fragment and Fab2; Rabbit IgG; Cat IgG1 and IgM; Ferret IgG1, IgM and IgA | NTRL, ELISA, FC, Therapeutic |
| Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human IgG1, IgM, IgG3, IgA, IgA1, Fab, Fab2, IgG2, IgG4 and IgE; Mouse IgG2b, IgM, Fab fragment and Fab2; Rabbit IgG; Cat IgM and IgG1; Ferret IgG1, IgM and IgA | NTRL, ELISA |
| Anti-Covid-19 & SARS-CoV Nucleoprotein [CR3018 (03-018)] | Human IgG1, IgM, IgG3, IgA, IgA1, IgGA2, Fab, Fab2 and IgG2; Mouse IgG2b, IgM, Fab fragment and Fab2; Rabbit IgG; Cat IgM and IgG1; Ferret IgG1, IgM and IgA | ELISA, IF |
| Anti-Covid-19 & SARS-CoV Nucleoprotein [CR3009 (03-009)] | Human IgG1, IgM, IgG3, IgA, IgA1, IgA2, Fab, Fab2 and IgG2; Mouse IgG2b, IgM, Fab fragment and Fab2; Rabbit IgG; Cat IgM and IgG1; Ferret IgG1, IgM and IgA | ELISA, IF |
| Anti-Spike protein (RBD) [Sb#14]] | Human IgG1, IgM, IgG3, and IgA; Mouse IgG1; Rabbit IgG; VHH | ELISA, Blocking |
| Anti-Spike protein (RBD) [Sb#15] | Human IgG1, IgM, IgG3, and IgA; Mouse IgG1; Rabbit IgG; VHH | ELISA, Blocking |
| Anti-Spike protein (RBD) [Sb#16] | Human IgG1, IgM, IgG3, and IgA; Mouse IgG1; Rabbit IgG; VHH | ELISA, Blocking |
| Anti-Spike protein (RBD) [Sb#42] | Human IgG1, IgM, IgG3, and IgA; Mouse IgG1; Rabbit IgG; VHH | ELISA, Blocking |
| Anti-Spike protein (RBD) [Sb#45] | Human IgG1, IgM, IgG3, and IgA; Mouse IgG1; Rabbit IgG; VHH | ELISA, Blocking |
| Anti-Spike protein (RBD) [Sb#68] | Human IgG1, IgM, IgG3, and IgA; Mouse IgG1; Rabbit IgG; VHH | ELISA, Blocking |
| Anti-SARS-CoV S glycoprotein [S227] | Human IgG1, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [S230] | Human IgG1, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [S215] | Human IgG1, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [S109] | Human IgG1, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [S124] | Human IgG1, IgM, IgG3, IgA1, Fab fragment and Fab2; Mouse IgG2b; Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [S222] | Human IgG1, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [S231] | Human IgG1, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [S228] | Human IgG1, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [S226] | Human IgG1, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [S217] | Human IgG1, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [S223] | Human IgG1, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [S110] | Human IgG1, IgM, IgG3, IgA1, Fab fragment and Fab2; Mouse IgG2b; Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [S225] | Human IgG1, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [4G2] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [5D3] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [6B1] | Human IgG, Human IgG2, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [5E4] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [1B5] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [4D4] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [11A] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [256] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL, ELISA |
| Anti-SARS-CoV S glycoprotein [A11] | Human IgG1, Human IgM, Mouse IgG, Mouse IgG2b, Mouse IgM, Rabbit IgG, scFv fragment | ELISA, IF, WB |
| Anti-SARS-CoV S glycoprotein [F26G9] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL, ELISA, IF |
| Anti-SARS-CoV S glycoprotein [F26G10] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL, ELISA, IF |
| Anti-SARS-CoV S glycoprotein [F26G19] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL, ELISA, IF, WB |
| Anti-MERS-CoV Spike Protein [D12] | Mouse IgG1, Rabbit IgG1 | NTRL, ELISA, IF |
| Anti-MERS-CoV Spike Protein [4c2] | Mouse IgG1, Rabbit IgG1 | NTRL, ELISA |
| Anti-MERS-CoV Spike Protein [3B12] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL |
| Anti-MERS-CoV Spike Protein [M14D3] | Human IgG1, Human IgM, Mouse IgG1, Mouse IgM, Mouse IgG2b, Rabbit IgG | NTRL |
| Anti-MERS-CoV Spike Protein [1F8] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL |
| Anti-MERS-CoV Spike Protein [3A1] | Human IgG, Human IgM, Mouse IgG, Mouse IgM, Rabbit IgG | NTRL |
| Anti-Bovine coronavirus [SF-3E4] | Mouse IgG1, Rabbit IgG1 | NTRL, ELISA, WB |
| Anti-SARS-CoV-2 and SARS-CoV nucleocapsid [mBG17] | Human IgG1, IgG2, IgG3, IgE, IgM, IgA1, Fab fragment and Fab2; Mouse IgG1, IgG2b, IgM, Fab fragment and Fab2; Rabbit IgG; Ferret IgG1, IgM and IgA; Cat IgG1 and IgM | WB, ELISA, IF |
| Anti-SARS-CoV-2 nucleocapsid [mBG86] | Human IgG1, IgG2, IgG3, IgM, IgA1, Fab fragment and Fab2; Mouse IgG1, IgA, IgM, IgG2b, Fab fragment and Fab2; Rabbit IgG; Ferret IgG1, IgM and IgA; Cat IgG1 and IgM | WB, ELISA, IF |
| Anti-Spike protein [EY6A] | Human IgG1, IgG2, IgA1, IgM, Fab fragment and Fab2; Mouse IgG2b and IgM; Rabbit IgG | NTRL, Surface Plasmon Resonance, therapeutic, ELISA, IF |
| Anti-Spike protein [SR4] | Human IgG1, IgM, IgG3, and IgA; Mouse IgG1; Rabbit IgG; VHH | Biolayer interferometry, FACS, NTRL, therapeutic, ELISA |
| Anti-Spike protein [MR3] | Human IgG1, IgM, IgG3, and IgA; Mouse IgG1; Rabbit IgG; VHH | Biolayer interferometry, FACS, NTRL, therapeutic, ELISA |
| Anti-Spike protein [Sb23] | Human IgG1, IgM, IgG3, and IgA; Mouse IgG1; Rabbit IgG; VHH | Biolayer interferometry, NTRL, ELISA |
| Anti-Covid-19 & SARS-CoV Nucleocapsid [1C7C7] | Human IgG1, IgM, IgA1, IgG2 and IgG4-S228P; Mouse IgG1, IgG2a, IgM, Fab fragment and Fab2; Rabbit IgG; Ferret IgG1, IgM and IgA; Cat IgG1 and IgM | WB, ELISA, FC, IHC |
| Anti-Spike protein [Ty1] | Human IgG1, IgM, IgG3, and IgA; Mouse IgG1; Rabbit IgG; VHH | Biolayer interferometry, inhibit, NTRL, ELISA, FC, IF |
| Anti-Spike protein [MR17] | Human IgG1, IgM, IgG3, and IgA; Mouse IgG1; Rabbit IgG; VHH | Biolayer interferometry, FACS, NTRL, therapeutic, ELISA |
| 抗體貨號 | 抗體名稱 | Antibody Species | Isotype | LCFormat | Heavy Chain modification | Display_Amount |
| Ab01680-1.6 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Mouse | Fab fragment | kappa | His-Tagged | 100 μg |
| Ab01680-1.6-BS | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Mouse | Fab fragment | kappa | His-Tagged | 1 mg |
| Ab01680-1.6-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Mouse | Fab fragment | kappa | His-Tagged | 500 μg |
| Ab01680-1.7 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Mouse | F(ab)2 | kappa | AbFab2™ His-Tagged | 100 μg |
| Ab01680-1.7-BS | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Mouse | F(ab)2 | kappa | AbFab2™ His-Tagged | 1 mg |
| Ab01680-1.7-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Mouse | F(ab)2 | kappa | AbFab2™ His-Tagged | 500 μg |
| Ab01680-10.0 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | IgG1 | kappa | 200 μg | |
| Ab01680-10.0-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | IgG1 | kappa | 1 mg | |
| Ab01680-10.3 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | IgG1 | kappa | Fc Silent™ | 200 μg |
| Ab01680-10.3-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | IgG1 | kappa | Fc Silent™ | 1 mg |
| Ab01680-10.6 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | Fab fragment | kappa | His-Tagged | 100 μg |
| Ab01680-10.6-BS | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | Fab fragment | kappa | His-Tagged | 1 mg |
| Ab01680-10.6-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | Fab fragment | kappa | His-Tagged | 500 μg |
| Ab01680-10.7 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | F(ab)2 | kappa | AbFab2™ His-Tagged | 100 μg |
| Ab01680-10.7-BS | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | F(ab)2 | kappa | AbFab2™ His-Tagged | 1 mg |
| Ab01680-10.7-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | F(ab)2 | kappa | AbFab2™ His-Tagged | 500 μg |
| Ab01680-11.0 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | IgG2 | kappa | 200 μg | |
| Ab01680-11.0-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | IgG2 | kappa | 1 mg | |
| Ab01680-12.1 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | IgG3 | kappa | 200 μg | |
| Ab01680-12.1-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | IgG3 | kappa | 1 mg | |
| Ab01680-15.0 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | IgM | kappa | 50 μg | |
| Ab01680-15.0-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | IgM | kappa | 500 μg | |
| Ab01680-16.0 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | IgA | kappa | 50 μg | |
| Ab01680-16.0-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Human | IgA | kappa | 500 μg | |
| Ab01680-21.0 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Mouse | IgM | kappa | 50 μg | |
| Ab01680-21.0-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Mouse | IgM | kappa | 500 μg | |
| Ab01680-23.0 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Rabbit | IgG | kappa | 200 μg | |
| Ab01680-23.0-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Rabbit | IgG | kappa | 1 mg | |
| Ab01680-3.0 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Mouse | IgG2b | kappa | 200 μg | |
| Ab01680-3.0-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Mouse | IgG2b | kappa | 1 mg | |
| Ab01680-3.3 | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Mouse | IgG2b | kappa | Fc Silent™ | 200 μg |
| Ab01680-3.3-BT | Anti-COVID-19 & SARS-CoV S glycoprotein [CR3022] | Mouse | IgG2b | kappa | Fc Silent™ | 1 mg |