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【CMXRos粒線體紅色螢光探針】Mito-Tracker Red CMXRos-APExBIO貨號 B8810

Mito-Tracker Red CMXRos| APExBIO貨號 B8810

A red-fluorescent probe that selectively labels mitochondria, and staining is retained if the cells need fixation after the mitochondria labeling

產品介紹

A red-fluorescent probe that selectively labels mitochondria, and staining is retained if the cells need fixation after the mitochondria labeling

Mito-Tracker Red CMXRos,粒線體紅色螢光探針(A red-fluorescent probe )也稱為 MitoMark Red I,是一種氧化紅色螢光探針,可選擇性標記粒線體。一些傳統的粒線體螢光探針,如四甲基玫瑰胺和羅丹明 123( rhodamine 123),被功能性粒線體(functional mitochondria)隔離。當粒線體膜電位喪失( mitochondria membrane potential)時,這些探針很容易從細胞中洗掉。這項特性限制了在需要用固定劑或其他影響粒線體功能的試劑處理細胞的實驗中的使用。 Mito-Tracker Red CMXRos 是 X-rosamine 的衍生物,它被動地擴散穿過活細胞的質膜並在活躍的粒線體中累積。同時,如果細胞在粒線體染色後需要固定,Mito-Tracker Red CMXRos 會保留在粒線體中。

Mito-Tracker Red CMXRos, also called MitoMark Red I, is an oxidized red fluorescent probe that selectively labels mitochondria. Some conventional fluorescent probes for mitochondria such as tetramethylrosamine and rhodamine 123, are sequestered by functional mitochondria. These probes are easily washed out of cells upon loss in the mitochondria membrane potential. This characteristic limits the use in experiments that require cells to be treated with fixatives or other regent that affect the function of the mitochondria. Mito-Tracker Red CMXRos is a derivative of X-rosamine, which passively diffuses across the plasma membrane of live cells and accumulates in active mitochondria. Meanwhile, Mito-Tracker Red CMXRos is retained in the mitochondria if the cells need fixation after the mitochondria staining.

Ex/Em 578/598
Synonyms MitoMark Red I
Storage The product should be stored at -20°C away from light and moisture.
Shipping Condition Blue ice
EXP Date This product should be stored at -20°C away from light and moisture. Stable for 1 year.
Physical Appearance Solid
M.Wt 531.52
Cas No. 167095-09-2
Formula C32H32Cl2N2O
Solubility Soluble in DMSO
Shipping Condition Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips We do not recommend long-term storage for the solution, please use it up soon.

 

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APExBIO提供優質的胜肽和生物分析試劑,廣泛產品線如Protease、Chromatin/Epigenetics表觀遺傳學、MAPK Signal、DNA Damege/DNA repair、細胞凋亡、腫瘤生物學、Stem cell等研究領域, 還提供定制的服務,包括多肽合成,抗體的生產和檢測的發展。產品線DNA/RNA prep kit、Drug Screening panel、Bioactive peptides、Growth factors、Biotinylation Reagents、tag peptides、amino Acids、Growth factors等。APExBIO產品質量都伴隨著證書的分析,高效液相色譜,質譜,和HMNR數據。

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