In vivo Functional Grade Antibodies

業界領先的品質低內毒素 ≤ 0.5 – ≤ 1.0 EU/mg。Assay Genie in vivo functional-grade antibodies 是高純度、低內毒素(low endotoxin )單株抗體，可用於轉化(translational)和臨床前( preclinical)動物研究以及體外功能測定(in vitro functional assays)。這些抗體具有業界最高的品質標準，沒有可檢測到的可浸出的 Protein A 或aggregates，內毒素(endotoxin)水平極低，純度高達 ≥ 98%。體內抗體(in vivo antibodies )在經過 cGMP 和 ISO 9001:2015 / ISO 13485:2015 認證的設施中生產，由於不含病原體（IDEXX Impact I PCR 小鼠病原體譜），因此可用於注射到動物體內。該系列低和超低內毒素抗體已經過測試，可用於功能研究，例如共刺激(co-stimulation)、耗竭(depletion)、阻斷(blocking)和中和實驗(neutralization experiments)以及 ELISA、FC、ICC、IHC-PE、IHC-FF 等應用、IP、WB 、ELISpot、CODEX® 和CyTOF®。這些抗體採用靈活的包裝尺寸，包括 1 毫克、5 毫克、25 毫克、50 毫克和 100 毫克包裝尺寸，也可根據要求提供客製化包裝。本目錄包括免疫檢查點抗體(immune checkpoint antibodies)等頂級標靶，如 PD-1 [clone RMP1-14]、PD-L1 (B7-H1) [clone 10F.9G2] 和 CTLA-4 [9H10]，以及關鍵標靶免疫細胞耗竭(immune cell depletion )，例如CD4、CD8 等。

活體用 (低內毒素) 抗小鼠 PD-1 抗體 [RMP1-14] | Assaygenie貨號IVMB0037

Anti-Mouse PD-1 Antibody [RMP1-14] In Vivo – Low Endotoxin

PD-1 是 B7 Ig 超家族( B7 Ig superfamily) 的 50-55 kD 成員。 PD-1 也是 T 細胞調節因子 CD28/CTLA-4 家族的成員，可能在淋巴細胞克隆選擇和周邊耐受中發揮作用。 PD-1的配體是PD-L1和PD-L2，也是B7 Ig超家族的成員。 PD-1 及其配體負調控免疫反應。 PD-L1 或 B7-Homolog 1 是一種 40 kD I 型跨膜蛋白，據報道可共刺激 T 細胞生長和細胞激素產生。 PD-1 與其配體 PD-L1 的相互作用對於抑制 T 細胞反應（包括 T 細胞增殖和細胞激素產生）至關重要。 PD-L1 在多種癌症中表現增加。抑制 PD-1 和 PD-L1 之間的相互作用可以透過改善體外 T 細胞反應( T-cell responses )並介導臨床前抗腫瘤活性來作為免疫檢查點(immune checkpoint blockade)阻斷。在檢查點抑制(checkpoint inhibition)領域，使用抗PD1與抗CTLA4合併治療對於腫瘤治療具有顯著的治療潛力。 PD-L2 是 PD-1 的 25 kD I 型跨膜配體。透過 PD-1，PD-L2 可以作為 T 細胞功能的共同抑制劑。阻斷 PD-L2 和 PD-1 相互作用的 mAb 可調節 T 細胞反應，包括增強 T 細胞(T cell proliferation)增殖和細胞激素(cytokine production)產生。

Product Name:	Anti-Mouse PD-1 (CD279) [RMP1-14] In Vivo Antibody – Low Endotoxin
Product Code:	IVMB0037
Size:	1mg, 5mg, 25mg, 50mg, 100mg
Clone:	RMP1-14
Protein:	PD-1
Product Type:	Monoclonal Antibody
Synonyms:	Programmed Death-1, CD279, PD 1
Isotype:	Rat IgG2a κ
Reactivity:	Mouse
Immunogen:	Mouse PD-1 transfected BHK cells
Applications:	B, FA, WB
Formulation:	This monoclonal antibody is aseptically packaged and formulated in 0.01 M phosphate buffered saline (150 mM NaCl) PBS pH 7.2 – 7.4 with no carrier protein, potassium, calcium or preservatives added.
Endotoxin Level:	< 1.0 EU/mg as determined by the LAL method
Purity:	≥95% monomer by analytical SEC >95% by SDS Page
Preparation:	Functional grade preclinical antibodies are manufactured in an animal free facility using only In vitro protein free cell culture techniques and are purified by a multi-step process including the use of protein A or G to assure extremely low levels of endotoxins, leachable protein A or aggregates.
Storage and Handling:	Functional grade preclinical antibodies may be stored sterile as received at 2-8°C for up to one month. For longer term storage, aseptically aliquot in working volumes without diluting and store at -80°C. Avoid Repeated Freeze Thaw Cycles.

低內毒素和超低內毒素有什麼不同？

Figure 1. Quality control for different lots of PD-1 [RMP1-14] antibody. All the in vivo antibodies undergo extensive quality control ensuring extreme lot-to-lot reproducibility. Endotoxin data for eight lots demonstrate that all lots were below the specification of ≤ 0.5 EU/mg as determined by the limulus amebocyte lysate (LAL) method (Fig. 1A). Analysis by size exclusion chromatography visualized by superimposing chromatograms for all nine lots, with overlapping retention times and minimal baseline noise (Fig. 1B). All lots show high purity as shown by non-reducing and reducing SDS-PAGE (Fig. 1C and 1D).IDEXX IMPACT I (PCR-based) Mouse Pathogen Profile for Purified In vivo Ultra Low Grade AntibodiesI

Antibodies and isotypes tested
Independent comparison of the in vivo efficacy and tolerability of clones of mAbs anti-PD-1 [RMP1-14 and 29F.1A12], anti-PD-L1 [10F.9G2], and anti-CTLA-4 [9H10] and isotype controls versus Vendor B using a CT26 syngeneic model (murine colorectal carcinoma derived from BALB/c mice). All antibodies had matching isotype controls, and phosphate-buffered
saline (PBS) was used as a control.

功效和耐受性基準測試

Independent comparison of the in vivo efficacy and tolerability of clones of mAbs anti-PD-1 [RMP1-14 and 29F.1A12], anti-PD-L1 [10F.9G2], and anti-CTLA-4 [9H10] and isotype controls versus Vendor B using a CT26 syngeneic model (murine colorectal carcinoma derived from BALB/c mice). All antibodies had matching isotype controls (Table 2), and phosphate-buffered saline (PBS) was used as a control.

Assay Genie SKU	Product Name	Isotype	Applications
IVMB0001	Anti-Mouse CD115 In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	B, CyTOF®, Depletion, FA, FC
IVMB0002	Anti-Mouse CD115 (CSF-1R) In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a κ	B, CyTOF®, Depletion, FA, FC
IVMB0003	Anti-Human IL-4 In Vivo Antibody – Low Endotoxin	Rat IgG1 κ	CyTOF®, IHC, N, WB
IVMB0004	Anti-Mouse IFNAR-1 In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1	B, ELISA, FC, IP, WB
IVMB0005	Anti-Mouse IL-1α In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG1	N, WB
IVMB0006	Anti-Mouse IL-1R (CD121a) In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	B, IP, WB
IVMB0007	Anti-Mouse TNFα In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	IP, N, WB
IVMB0008	Anti-Mouse TNFα In Vivo Antibody – Ultra Low Endotoxin	Armenian Hamster IgG	IP, N, WB
IVMB0009	Anti-Mouse H-2Kb (MHC Class I) [Y-3] In Vivo Antibody – Low Endotoxin	Mouse IgG2b κ	FA, ICC, IP, WB
IVMB0010	Anti-Mouse H-2Kb (MHC Class I) [Y-3] In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG2b κ	FA, ICC, IP, WB
IVMB0011	Anti-Human CD25 (IL-2Rα) [7G7B6] In Vivo Antibody – Low Endotoxin	Mouse IgG2a	ELISA, FC, IF Staining, IP, WB
IVMB0012	Anti-Human CD4 [OKT-4] In Vivo Antibody – Low Endotoxin	Mouse IgG2b κ	CODEX®, ELISA, FC, ICC, IF Staining, IHC FF, IHC FFPE, IP, N, WB
IVMB0013	Anti-Human CD40 [G28.5] In Vivo Antibody – Low Endotoxin	Mouse IgG1 κ	FA, FC
IVMB0014	Anti-Human HLA-A, B, C (MHC Class I) In Vivo Antibody – Low Endotoxin	Mouse IgG2a κ	B, CODEX®, FC, IHC FF, IP, WB
IVMB0015	Anti-Human HLA-A, B, C (MHC Class I) In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG2a κ	B, CODEX®, FC, IHC FF, IP, WB
IVMB0016	Anti-Human CD71 In Vivo Antibody – Low Endotoxin	Mouse IgG1	FC, WB
IVMB0017	Anti-Human CD71 In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1	FC, IHC
IVMB0018	Anti-Human CD20 In Vivo Antibody – Low Endotoxin	Mouse IgG2b κ	CyTOF®, FC, WB
IVMB0019	Anti-Human CD20 In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG2b κ	CyTOF®, FC, WB
IVMB0020	Anti-Human HLA-DR (MHC Class II) In Vivo Antibody – Low Endotoxin	Mouse IgG2a	B, CODEX®, CyTOF®, FC, IHC FF, IP, WB
IVMB0021	Anti-Human HLA-DR (MHC Class II) In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG2a	B, CODEX®, CyTOF®, Depletion, FC, IHC FF, IP, WB
IVMB0022	Anti-Mouse IFNγ [XMG1.2] In Vivo Antibody – Low Endotoxin	Rat IgG1 κ	CyTOF®, ELISA Cap, ELISPOT, ICFC, IHC FF, N, WB
IVMB0023	Anti-Mouse IL-12 In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	ELISA, ICFC, IP, N, WB
IVMB0024	Anti-Mouse IL-2 [JES6-1A12] In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	IP, N, WB
IVMB0025	Anti-Mouse Ly-6G In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	CODEX®, CyTOF®, Depletion, FC, IHC FF, WB
IVMB0026	Anti-Mouse Ly-6G In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a	CODEX®, CyTOF®, Depletion, FC, IHC FF, WB
IVMB0027	Anti-Mouse CD32/CD16 In Vivo Antibody – Low Endotoxin	Rat IgG2b	B, CODEX®, FA, FC, IHC FF, IP, WB
IVMB0028	Anti-Mouse CD32/CD16 In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b	CODEX®, FC, IHC FF, IP, WB
IVMB0029	Anti-Mouse CD172a In Vivo Antibody – Low Endotoxin	Rat IgG1 κ	B, CyTOF®, FC, IHC FF, IP
IVMB0030	Anti-Mouse CD172a In Vivo Antibody – Ultra Low Endotoxin	Rat IgG1 κ	B, CyTOF®, FC, IHC FF, IP
IVMB0031	Anti-Mouse PD-1 (CD279) [29F.1A12] In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	B, CODEX®, CyTOF®, FC, IHC FF, WB
IVMB0032	Anti-Mouse PD-1 (CD279) [29F.1A12] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a κ	B, CODEX®, CyTOF®, FC, IHC FF, WB
IVMB0033	Anti-Mouse IFNγ [H22] In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	IP, N, WB
IVMB0034	Anti-Mouse IFNγ [H22] In Vivo Antibody – Ultra Low Endotoxin	Armenian Hamster IgG	ELISA, IF, IP, N, WB
IVMB0035	Anti-Mouse γ/δ (TCR) In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	Depletion, FC, IP
IVMB0036	Anti-Mouse γ/δ (TCR) In Vivo Antibody – Ultra Low Endotoxin	Armenian Hamster IgG	Depletion, FC, IP
IVMB0037	Anti-Mouse PD-1 (CD279) [RMP1-14] In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	B, FA, WB
IVMB0038	Anti-Mouse PD-1 (CD279) [RMP1-14] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a κ	B, FA, WB
IVMB0039	Anti-Mouse PD-L2 In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	FC, IHC FF, IP, WB
IVMB0040	Anti-Mouse CD11a [FD441.8] In Vivo Antibody – Low Endotoxin	Rat IgG2b	FA, FC, WB
IVMB0041	Anti-Mouse CD11a [FD441.8] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b	FC
IVMB0042	Anti-Mouse CD11b In Vivo Antibody – Low Endotoxin	Rat IgG2b κ	CODEX®, CyTOF®, FA, FC, ICC, IHC FF
IVMB0043	Anti-Mouse CD11b In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b κ	CODEX®, CyTOF®, FA, FC, ICC, IHC FF
IVMB0044	Anti-Mouse CD127 (IL-7Rα) In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	B, CyTOF®, FA, FC, IF Staining, IHC FF, IP, WB
IVMB0045	Anti-Mouse 4-1BB In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	ELISA, FA, WB
IVMB0046	Anti-Mouse 4-1BB In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a	ELISA, FA, WB
IVMB0047	Anti-Mouse CTLA-4 [9H10] In Vivo Antibody – Low Endotoxin	Syrian Hamster IgG	B, WB
IVMB0048	Anti-Mouse CTLA-4 [9H10] In Vivo Antibody – Ultra Low Endotoxin	Syrian Hamster IgG	B, WB
IVMB0049	Anti-Mouse CTLA-4 (CD152) In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG1 κ	FA, FC, IP, WB
IVMB0050	Anti-Mouse CTLA-4 (CD152) In Vivo Antibody – Ultra Low Endotoxin	Armenian Hamster IgG1	FA, FC, IP, WB
IVMB0051	Anti-Mouse CD19 In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	B, CODEX®, Depletion, FC, IHC FF, IP, WB
IVMB0052	Anti-Mouse CD19 In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a	B, CODEX®, Depletion, FC, IHC FF, IP, WB
IVMB0053	Anti-Mouse CD209b In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG1 κ	B, FC, IHC FF, WB
IVMB0054	Anti-Mouse CD209b In Vivo Antibody – Ultra Low Endotoxin	Armenian Hamster IgG1 κ	B, FC, IHC FF, WB
IVMB0055	Anti-Mouse RANKL In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	B, FC, IP, WB
IVMB0056	Anti-Mouse CD28 In Vivo Antibody – Low Endotoxin	Syrian Hamster IgG	B, Costim, CyTOF®, FC, IHC FF, IP, WB
IVMB0057	Anti-Mouse CD28 In Vivo Antibody – Ultra Low Endotoxin	Syrian Hamster IgG	B, Costim, CyTOF®, FA, IP, WB
IVMB0058	Anti-Mouse CD3ε [145-2C11] In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	Act, B, CODEX®, CyTOF®, Depletion, FA, FC, ICC, IF, IHC FF, WB
IVMB0059	Anti-Mouse CD3ε [145-2C11] In Vivo Antibody – Ultra Low Endotoxin	Armenian Hamster IgG	Act, B, CODEX®, CyTOF®, Depletion, FA, FC, ICC, IF, IHC FF, WB
IVMB0060	Anti-Mouse CD4 [GK1.5] In Vivo Antibody – Low Endotoxin	Rat IgG2b κ	B, Costim, CyTOF®, Depletion, FA, FC, IHC, IP
IVMB0061	Anti-Mouse CD4 [GK1.5] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b κ	B, Costim, CyTOF®, Depletion, FA, FC, IHC, IP
IVMB0062	Anti-Mouse CD54 [YN1/1.7.4] In Vivo Antibody – Low Endotoxin	Rat IgG2b κ	CODEX®, CyTOF®, FA, FC, IHC FF, IP, WB
IVMB0063	Anti-Mouse CD54 [YN1/1.7.4] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b κ	CODEX®, CyTOF®, FA, FC, IHC FF, IP, WB
IVMB0064	Anti-Mouse CD62L In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	B, CyTOF®, FA, FC, IHC FF, IP, WB
IVMB0065	Anti-Mouse CD62L In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a κ	B, CyTOF®, FC, IHC FF, IP, WB
IVMB0066	Anti-Mouse CD80 In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	B, CyTOF®, IP, WB
IVMB0067	Anti-Mouse CD80 In Vivo Antibody – Ultra Low Endotoxin	Armenian Hamster IgG	B, CyTOF®, IP, WB
IVMB0068	Anti-Mouse CD8a (Ly 2) In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	B, CODEX®, CyTOF®, Depletion, FC, IHC FF, IP, WB
IVMB0069	Anti-Mouse CD8a (Ly 2) In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a κ	B, CODEX®, CyTOF®, Depletion, FC, IHC FF, IP, WB
IVMB0070	Anti-Mouse CD8a (Ly 2.2) In Vivo Antibody – Low Endotoxin	Rat IgG2b	Depletion, FA, FC, ICC, IF Staining, IHC FFPE, IP
IVMB0071	Anti-Mouse CD8a (Ly 2.2) In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b	Depletion, FA, FC, ICC, IF Staining, IHC FFPE, IP
IVMB0072	Anti-Mouse CTLA-4 [9D9] In Vivo Antibody – Low Endotoxin	Mouse IgG2b	FA, WB
IVMB0073	Anti-Mouse CTLA-4 [9D9] In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG2b	FA, WB
IVMB0074	Anti-Mouse TCR V gamma 2 In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	Depletion, FC, IP
IVMB0075	Anti-Mouse Vγ2 TCR In Vivo Antibody – Ultra Low Endotoxin	Armenian Hamster IgG	Depletion, FC, IP
IVMB0076	Anti-Mouse GM-CSF In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	N, WB
IVMB0077	Anti-Mouse GM-CSF In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a	N, WB
IVMB0078	Anti-Mouse/Human CD44 [IM7] In Vivo Antibody – Low Endotoxin	Rat IgG2b κ	CODEX®, CyTOF®, ELISA Det, FC, ICC, IHC FF, IHC FFPE, IP, WB
IVMB0079	Anti-Mouse/Human CD44 [IM7] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b	CODEX®, CyTOF®, ELISA Det, FC, ICC, IHC FF, IHC FFPE, IP, WB
IVMB0080	Anti-Mouse/Human TGF-β1, 2, 3 In Vivo Antibody – Low Endotoxin	Mouse IgG1	IHC, N, WB
IVMB0081	Anti-Mouse/Human TGF-β1, 2, 3 In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1	IHC, N, WB
IVMB0082	Anti-Mouse CD278 (ICOS) In Vivo Antibody – Low Endotoxin	Rat IgG2b κ	B, FA, WB
IVMB0083	Anti-Mouse CD278 (ICOS) In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b	B, FA, WB
IVMB0084	Anti-Mouse IL-10 In Vivo Antibody – Low Endotoxin	Rat IgG1 κ	CyTOF®, N, WB
IVMB0085	Anti-Mouse IL-1β In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	IP, N, WB
IVMB0086	Anti-Mouse IL-4 In Vivo Antibody – Low Endotoxin	Rat IgG1 κ	CyTOF®, ELISA Cap, ELISPOT, FA, ICC, IHC, IP, N
IVMB0087	Anti-Human/Mouse Integrin β7 In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	B, CyTOF®, FC, IP
IVMB0088	Anti-Mouse CD223 (LAG-3) In Vivo Antibody – Low Endotoxin	Rat IgG1 κ	B, FA, IP, WB
IVMB0089	Anti-Mouse LPAM-1 In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	B, FC, IHC FF, IP
IVMB0090	Anti-Mouse LPAM-1 In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a κ	B, FC, IHC FF, IP
IVMB0091	Anti-Mouse Ly-6G/Ly-6C (Gr-1) In Vivo Antibody – Low Endotoxin	Rat IgG2b	CyTOF®, Depletion, IHC FF, IP, WB
IVMB0092	Anti-Mouse Ly-6G/Ly-6C (Gr-1) In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b	CyTOF®, Depletion, FC, IHC FF, IHC FFPE, IP, WB
IVMB0093	Anti-Mouse CD8b.2 In Vivo Antibody – Low Endotoxin	Rat IgG1 κ	Depletion, FA, FC, ICC, WB
IVMB0094	Anti-Mouse CD8b.2 In Vivo Antibody – Ultra Low Endotoxin	Rat IgG1	Depletion, FA, FC, ICC, WB
IVMB0095	Anti-Mouse PD-L1 (B7-H1) [10F.9G2] In Vivo Antibody – Low Endotoxin	Rat IgG2b κ	B, CODEX®, FC, IHC FF, WB
IVMB0096	Anti-Mouse PD-L1 (B7-H1) [10F.9G2] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b κ	B, CODEX®, FA, IHC FF, WB
IVMB0097	Anti-Mouse CD366 (Tim-3) In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	B, CODEX®, FC, IF Staining, IHC, IHC FF
IVMB0098	Anti-Mouse CD120b (TNFR2) In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	B, IP, WB
IVMB0099	Anti-Mouse CD120b (TNFR2) In Vivo Antibody – Ultra Low Endotoxin	Armenian Hamster IgG	B, ELISA Cap, FC, IP, WB
IVMB0100	Anti-Mouse NK1.1 In Vivo Antibody – Low Endotoxin	Mouse IgG2a κ	B, CyTOF®, Depletion, FC, IP, WB
IVMB0101	Anti-Mouse NK1.1 In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG2a κ	B, CyTOF®, Depletion, FC, IP, WB
IVMB0102	Anti-Human Alpha Defensin-5 [8C8] In Vivo Antibody – Low Endotoxin	Mouse IgG2b κ	Dot, ELISA, IHC FFPE, WB
IVMB0103	Anti-Human CD119 (IFN-γ Rα Chain) In Vivo Antibody – Low Endotoxin	Mouse IgG1	FA, FC
IVMB0104	Anti-Human CD119 (IFN-γ Rα Chain) In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1	FA, FC
IVMB0105	Anti-Human CD11a In Vivo Antibody – Low Endotoxin	Mouse IgG2a	Costim, FC, WB
IVMB0106	Anti-Human CD11a In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG2a	Costim, FC, WB
IVMB0107	Anti-Human CD11b In Vivo Antibody – Low Endotoxin	Mouse IgG1 κ	CODEX®, FC, IF Staining, IHC FF
IVMB0108	Anti-Human CD11b In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1 κ	CODEX®, FC, IF Staining, IHC FF
IVMB0109	Anti-Human CD11c In Vivo Antibody – Low Endotoxin	Mouse IgG1 κ	B, CyTOF®, FA, FC, WB
IVMB0110	Anti-Human CD11c In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1 κ	B, CyTOF®, FA, FC, IHC FF, WB
IVMB0111	Anti-Human CD14 In Vivo Antibody – Low Endotoxin	Mouse IgG2a	FC, WB
IVMB0112	Anti-Human CD16 [3G8] In Vivo Antibody – Low Endotoxin	Mouse IgG1 κ	B, CyTOF®, FC, IHC FF, IP
IVMB0113	Anti-Human CD16 [3G8] In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1 κ	B, CyTOF®, FC, IHC FF, IP
IVMB0114	Anti-Human CD2 In Vivo Antibody – Low Endotoxin	Mouse IgG2a	Costim, FC, IHC, WB
IVMB0115	Anti-Mouse PD-L2 (CD273) In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1	B, FC, WB
IVMB0116	Anti-Mouse/Human PD-L2 (CD273) In Vivo Antibody – Low Endotoxin	Mouse IgG1	B, FC
IVMB0117	Anti-Human CD3 [UCHT-1] In Vivo Antibody – Low Endotoxin	Mouse IgG1 κ	Act, CODEX®, CyTOF®, FC, IF Staining, IHC FF, IP, WB
IVMB0118	Anti-Human CD3 In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1 κ	CODEX®, CyTOF®, FC, IF Staining, IHC FF, IP, WB
IVMB0119	Anti-Human CD38 [OKT10] In Vivo Antibody – Low Endotoxin	Mouse IgG1	FC
IVMB0120	Anti-Human CD38 [OKT10] In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1	FC
IVMB0121	Anti-Human CD62L In Vivo Antibody – Low Endotoxin	Mouse IgG1	B, CODEX®, FC, IF, IHC FF, WB
IVMB0122	Anti-Human CD62L In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1	B, CODEX®, FC, IF, IHC FF, WB
IVMB0123	Anti-Human CD7 In Vivo Antibody – Low Endotoxin	Mouse IgG1 κ	FC, IF Staining
IVMB0124	Anti-Human CD8 In Vivo Antibody – Low Endotoxin	Mouse IgG2a	FA, FC, WB
IVMB0125	Anti-Human CD8 In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG2a	FA, FC, WB
IVMB0126	Anti-Human EGFR In Vivo Antibody – Low Endotoxin	Mouse IgG2b κ	IHC, WB
IVMB0127	Anti-Human EGFR In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG2b κ	WB
IVMB0128	Anti-Human Fibulin-4 [5G11] In Vivo Antibody – Low Endotoxin	0	IF Microscopy, IF Staining, IHC FFPE, WB
IVMB0129	Anti-Human Hepsin [3H10.1] In Vivo Antibody – Low Endotoxin	Mouse IgG1 κ	ELISA, FC
IVMB0130	Anti-Human HLA A2,B7 (MHC Class I) In Vivo Antibody – Low Endotoxin	Mouse IgG1	FC
IVMB0131	Anti-Human HLA-DP (MHC Class II) Monomorphic In Vivo Antibody – Low Endotoxin	Mouse IgG3	FC, ICC
IVMB0132	Anti-Human HLA-DQ (MHC Class II) In Vivo Antibody – Low Endotoxin	Mouse IgG2a	ELISA, FC, IP, WB
IVMB0133	Anti-Human HLA-DQ (MHC Class II) In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG2a	ELISA, FC, IP, WB
IVMB0134	Anti-Human ICAM-1 In Vivo Antibody – Low Endotoxin	Mouse IgG1	FC, IHC FFPE, IP, WB
IVMB0135	Anti-Human ICAM-1 In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1	FC, IHC FFPE, IP, WB
IVMB0136	Anti-Human TCR Vα24-Jα18 (iNKT cell) In Vivo Antibody – Low Endotoxin	Mouse IgG1 κ	CyTOF®, FC
IVMB0137	Anti-Human TCR Vα24-Jα18 (iNKT cell) In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG1 κ	CyTOF®, FC
IVMB0138	Anti-Mouse CD318 In Vivo Antibody – Low Endotoxin	Mouse IgG2b κ	FC
IVMB0139	Anti-Mouse CD11a [I21/7] In Vivo Antibody – Low Endotoxin	Rat IgG2a	FA, FC
IVMB0140	Anti-Mouse CD11a [I21/7] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a	FC
IVMB0141	Anti-Mouse CD11c In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	B, CODEX®, CyTOF®, IHC FF, WB
IVMB0142	Anti-Mouse CD120a (TNFR1) [55R-170] In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	B, IP, WB
IVMB0143	Anti-Mouse CD120a (TNFR1) [55R-593] In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	IP, WB
IVMB0144	Anti-Mouse CD120a (TNFR1) [55R-170] In Vivo Antibody – Ultra Low Endotoxin	Armenian Hamster IgG	B, FC, IP, WB
IVMB0145	Anti-Mouse CD120a (TNFR1) [55R-593] In Vivo Antibody – Ultra Low Endotoxin	Armenian Hamster IgG	FC, IP, WB
IVMB0146	Anti-Mouse CD155 (PVR) In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	FC
IVMB0147	Anti-Mouse CD155 (PVR) In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a κ	FC
IVMB0148	Anti-Mouse CD25 In Vivo Antibody – Low Endotoxin	Rat IgG1 λ	B, CODEX®, Depletion, FA, FC, IHC FF, IP, WB
IVMB0149	Anti-Mouse CD25 In Vivo Antibody – Ultra Low Endotoxin	Rat IgG1 λ	B, CODEX®, Depletion, FA, FC, IHC FF, IP, WB
IVMB0150	Anti-Mouse CD3ε [500A2] In Vivo Antibody – Low Endotoxin	Syrian Hamster IgG2a κ	B, FC, IHC FF
IVMB0151	Anti-Mouse CD3ε [500A2] In Vivo Antibody – Ultra Low Endotoxin	Syrian Hamster IgG2a κ	B, FC, IHC FF
IVMB0152	Anti-Mouse CD40 In Vivo Antibody – Low Endotoxin	Rat IgG2a	Act, FA, FC
IVMB0153	Anti-Mouse CD40 [FGK45] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a	Act, FA, WB
IVMB0154	Anti-Mouse CD8 In Vivo Antibody – Low Endotoxin	Rat IgG2b κ	Depletion, FC, IHC FF, WB
IVMB0155	Anti-Mouse CD8 [YTS 169] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b κ	Depletion, FC, IHC FF, WB
IVMB0156	Anti-Mouse CD86 In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	B, WB
IVMB0157	Anti-Mouse CD86 In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a κ	B, ELISA, WB
IVMB0158	Anti-Mouse CD90 (Thy-1) [T24/31] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG	Depletion, FA, FC, WB
IVMB0159	Anti-Mouse CD90 (Thy-1) [HK2.1] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2c	FA, WB
IVMB0160	Anti-Mouse CD90 (Thy-1) [HK2.1] In Vivo Antibody – Low Endotoxin	Rat IgG2c	FA, WB
IVMB0161	Anti-Mouse CD90 (Thy-1) [T24/31] In Vivo Antibody – Low Endotoxin	Rat IgG2b κ	Depletion, FA, FC, WB
IVMB0162	Anti-Mouse CD90.2 (Thy 1.2) In Vivo Antibody – Low Endotoxin	Rat IgG2b κ	CODEX®, Costim, CyTOF®, Depletion, FC, IHC FF, WB
IVMB0163	Anti-Mouse CD90.2 (Thy-1.2) In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b κ	Costim, CyTOF®, Depletion, FC, IHC FF, WB
IVMB0164	Anti-Mouse Dendritic Cells In Vivo Antibody – Low Endotoxin	Rat IgG2b κ	WB
IVMB0165	Anti-Mouse Dendritic Cells In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2b κ	WB
IVMB0166	Anti-Mouse H-2b In Vivo Antibody – Low Endotoxin	Mouse IgG1 κ	FA
IVMB0167	Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a	B, IP, WB
IVMB0168	Anti-Mouse ICAM-1 (CD54) [BE29G1] In Vivo Antibody – Low Endotoxin	Rat IgG2a	B, IP, WB
IVMB0169	Anti-Mouse CD370 In Vivo Antibody – Low Endotoxin	Rat IgG1	FC, IF, WB
IVMB0170	Anti-Mouse CD70 In Vivo Antibody – Low Endotoxin	Mouse IgG2a κ	B, ELISA, FA, FC, IF
IVMB0171	Anti-Mouse IFNß In Vivo Antibody – Low Endotoxin	Mouse IgG2a	B, FA, N, WB
IVMB0172	Anti-Mouse IFNß In Vivo Antibody – Ultra Low Endotoxin	Mouse IgG2a	B, FA, N, WB
IVMB0173	Anti-Mouse IFNα In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG1	B, FA, N, WB
IVMB0174	Anti-Mouse IFNα In Vivo Antibody – Ultra Low Endotoxin	Armenian Hamster IgG1	B, FA, N, WB
IVMB0175	Anti-Mouse IFNβ In Vivo Antibody – Low Endotoxin	Armenian Hamster IgG	N, WB
IVMB0176	Anti-Mouse Ly-6C [7B10] In Vivo Antibody – Low Endotoxin	Armenian Hamster IgM	WB
IVMB0177	Anti-Mouse Ly-6C [HK1.4] In Vivo Antibody – Low Endotoxin	Rat IgG2c	CODEX®, CyTOF®, IHC FF, IP, WB
IVMB0178	Anti-Mouse H-2Kd (MHC Class I) In Vivo Antibody – Low Endotoxin	Mouse IgG1 κ	FC, WB
IVMB0179	Anti-Mouse/Human CD45R [RA3-6B2] In Vivo Antibody – Ultra Low Endotoxin	Rat IgG2a κ	Act, CODEX®, CyTOF®, Depletion, FA, FC, IHC FF, IP
IVMB0180	Anti-Mouse/Human CD45R (B220) [RA3-6B2] In Vivo Antibody – Low Endotoxin	Rat IgG2a κ	Act, CODEX®, CyTOF®, Depletion, FA, FC, IHC FF, IP
IVMB0181	Anti-Mouse/Rat CD126 (IL-6Rα) In Vivo Antibody – Low Endotoxin	Rat IgG2b κ	FA, FC, N, WB
IVMB0182	Armenian Hamster IgG Isotype Control – Low Endotoxin	Armenian Hamster IgG	FC
IVMB0183	Armenian Hamster IgG Isotype Control – Ultra Low Endotoxin	Armenian Hamster IgG1	FC
IVMB0184	Mouse IgG1 Isotype Control [HKSP] – Low Endotoxin	Mouse IgG1
IVMB0185	Mouse IgG1 Isotype Control [HKSP84] – Low Endotoxin	Mouse IgG1
IVMB0186	Mouse IgG1 Isotype Control [HKSP84] – Ultra Low Endotoxin	Mouse IgG1
IVMB0187	Mouse IgG1 Isotype Control [HKSP] – Ultra Low Endotoxin	Mouse IgG1
IVMB0188	Mouse IgG2a Isotype Control – Low Endotoxin	Mouse IgG2a
IVMB0189	Mouse IgG2a Isotype Control – Ultra Low Endotoxin	Mouse IgG2a κ
IVMB0190	Mouse IgG2b Isotype Control – Low Endotoxin	Mouse IgG2b κ
IVMB0191	Mouse IgG2b Isotype Control – Ultra Low Endotoxin	Mouse IgG2b
IVMB0192	Mouse IgG3 Isotype Control – Low Endotoxin	Mouse IgG3
IVMB0193	Mouse IgG3 Isotype Control – Ultra Low Endotoxin	Mouse IgG3
IVMB0194	Mouse IgM Isotype Control – Low Endotoxin	Mouse IgM
IVMB0195	Mouse IgM Isotype Control – Ultra Low Endotoxin	Mouse IgM
IVMB0196	Rat IgG1 Isotype Control – Low Endotoxin	Rat IgG1
IVMB0197	Rat IgG1 Isotype Control – Ultra Low Endotoxin	Rat IgG1
IVMB0198	Rat IgG2a Isotype Control – Ultra Low Endotoxin	Rat IgG2a
IVMB0199	Rat IgG2a Isotype Control – Low Endotoxin	Rat IgG2a
IVMB0200	Rat IgG2b Isotype Control – Low Endotoxin	Rat IgG2b
IVMB0201	Rat IgG2b Isotype Control – Ultra Low Endotoxin	Rat IgG2b κ
IVMB0202	Anti-Mouse IFNAR-1 In Vivo Antibody – Low Endotoxin	Mouse IgG1	B,ELISA,FC,IP,WB