PS-341 | A proeasome inhibitor抑制劑 | 貨號1846  

產品介紹: 有效（Ki = 0.6nM），特異性和可逆蛋白酶體抑制劑。 它抑制IC 50為0.1μM的H460細胞（人非小細胞肺癌細胞系）的細胞增殖。

Alternate Name	MG-341; ((R)-3-Methyl-1-((S)-3-phenyl-2-(pyrazine-2-carboxamido)propanamido)butyl)boronic acid
Appearance	White to off-white solid
CAS #	179324-69-7
Molecular Formula	C₁₉H₂₅BN₄O₄
Molecular Weight	384.24
Purity	≥99% by HPLC
Solubility	DMSO (200mg/ml) or EtOH (200 mg/ml)
SMILES	B(C(CC(C)C)NC(=O)C(CC1=CC=CC=C1)NC(=O)C2=NC=CN=C2)(O)O
InChi	InChI=1S/C19H25BN4O4/c1-13(2)10-17(20(27)28)24-18(25)15(11-14-6-4-3-5-7-14)23-19(26)16-12-21-8-9-22-16/h3-9,12-13,15,17,27-28H,10-11H2,1-2H3,(H,23,26)(H,24,25)/t15-,17-/m0/s1
InChi Key	GXJABQQUPOEUTA-RDJZCZTQSA-N
PubChem CID	387447
MDL Number	MFCD09056737