抗病毒系列商品->>乙醯半胱氨酸(Acetylcysteine) 

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乙醯半胱氨酸(Acetylcysteine)  | Antioxidant;mucolytic agent CAS#616-91-1 APExBIO貨號A8356

Antioxidant;mucolytic agent

產品介紹

乙醯半胱氨酸(Acetylcysteine)是半胱氨(CYSTEINE)酸的 N-乙酰基衍生物。它用作粘液溶解劑(mucolytic agent)以降低粘液分泌物(mucous secretions)的粘度(viscosity)。由於活性氧中間體(reactive oxygen intermediate)抑制病毒刺激，它還被證明對 HIV 患者俱有抗病毒作用。

 

Storage	Store at -20°C
M.Wt	163.19
Cas No.	616-91-1
Formula	C5H9NO3S
Synonyms	N-acetylcysteine; N-acetyl-L-cysteine; NAC; Acetadote
Solubility	≥44.6 mg/mL in H2O; ≥53.3 mg/mL in EtOH; ≥8.16 mg/mL in DMSO
Chemical Name	(2R)-2-acetamido-3-sulfanylpropanoic acid
SDF	Download SDF
Canonical SMILES	CC(=O)NC(CS)C(=O)O
Shipping Condition	Small Molecules with Blue Ice, Modified Nucleotides with Dry Ice.
General tips	For obtaining a higher solubility, please warm the tube at 37°C and shake it in the ultrasonic bath for a while. We do not recommend long-term storage for the solution, please use it up soon.

Product Citation

1. • 1. PIUS REYDERG AGYEMANG. “Profifiling of FDA-Approved and Clinical Trial Drugs Revealed Shared Cytotoxicity And Collateral Sensitivity In Resistant (H69ar) And Non-Resistant (H69) Small Cell Lung Cancer Cells. (Drug Repurposing in Cancer Chemotherapy).” South Dakota State University 2021.
   • 2. Jing Wu, Yan-Qiu You, et al. “DDX5-targeting fully human monoclonal autoantibody inhibits proliferation and promotes differentiation of acute promyelocytic leukemia cells by increasing ROS production.” Cell Death & Disease volume 11, Article number: 552 (2020);20 July 2020. PMID:32690860
   • 3. Mahnaz Maddah, Mohammad A Mandegar, et al. “Quantifying drug-induced structural toxicity in hepatocytes and cardiomyocytes derived from hiPSCs using a deep learning method.” J Pharmacol Toxicol Methods. 2020 Sep;105:106895. PMID:32629158
   • 4. Wang Z, Chen J, et al. “cGAS/STING axis mediates a topoisomerase II inhibitor-induced tumor immunogenicity.” J Clin Invest. 2019 Aug 13;130:4850-4862. PMID:31408442
   • 5. Ye J, Xue M, et al. “Diosbulbin B-Induced Mitochondria-Dependent Apoptosis in L-02 Hepatocytes is Regulated by Reactive Oxygen Species-Mediated Autophagy.” Front Pharmacol. 2019 Jun 19;10:676. PMID:31275148

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