Human CD86/B7-2 protein, His tag (Animal-Free)重組蛋白 |貨號PRP2023

細胞因子(Cytokine)++–*

細胞因子(Cytokine)作為一種獨特的細胞信號轉導(cell signal transduction)分子，在細胞增殖(cell proliferation)和發育(development)中發揮著重要作用。 Abbkine 為癌症、細胞凋亡、內分泌學、免疫學、神經科學、蛋白酶和乾細胞研究提供細胞因子，包括白細胞介素(interleukin)、趨化因子(chemokine)、集落刺激因子 (colony stimulating factor , CSF)、干擾素(interferon)和轉化生長因子 (transforming growth factor , TGF) 和腫瘤壞死因子 (tumor necrosis factor , TNF) 家族。

Abbkine 為您提供細胞因子(Cytokine)，包括白細胞介素、趨化因子、集落刺激因子 (CSF)、干擾素、轉化生長因子 (TGF) 和腫瘤壞死因子 (TNF)，用於癌症、細胞凋亡、內分泌學、免疫學、神經科學、蛋白酶和幹細胞研究。這些細胞因子經每微克蛋白質內毒素，LAL法測定含量小於1.0EU。純度在95%以上，每個細胞因子都配備了1 mL與細胞因子最相容的再溶解緩衝液，因此再溶解後產品性能更穩定。過嚴格驗證，可滿足開發人員對高質量、高生物活性和有競爭力的價格的需求。

(Animal-Free) Abbkine細胞培養物（真核細胞）的非動物細胞因子(Animal-free cytokines)是利用非動物(non-animal)原料和表達系統生產的，表達系統中的培養基是無血清、無動物、化學成分透明的。

產品介紹:

分化簇 86 (Cluster of Differentiation 86, CD86) 也稱為 B 淋巴細胞活化抗原 B7-2(B-lymphocyte activation antigen)，是一種 I 型膜蛋白(type I membrane protein)，是免疫球蛋白超家族(immunoglobulin superfamily)的成員，在交叉指狀樹突細胞(interdigitating dendritic cells)、朗格漢斯細胞(Langerhans cells)、外周血樹突細胞(peripheral blood dendritic cells)上組成型表達。細胞、記憶B細胞和T helper cells)。 B7-2 主要作為單體存在於細胞表面，並與兩種共刺激受體 CD28 和 T 細胞上表達的細胞毒性 T 淋巴細胞相關抗原 4 (cytotoxic T lymphocyte-associated antigen 4 , CTLA-4) 相互作用，從而誘導調節 T 細胞活化和耐受性、細胞因子的產生和 CTL 的產生。表明由 CD86 介導的 B 和 T 輔助細胞之間的接觸促進了正常 B 細胞和 B 細胞淋巴瘤的增殖和 IgG 分泌的信號。最近的研究表明，CD86 還促進成熟 APC repertoire的產生，並促進 APC 功能和存活。 CD86在慢性血液透析(chronic hemodialysis)、過敏性肺部炎症(allergic pulmonary inflammation)、關節炎(arthritis)和抗病毒反應(antiviral responses)中具有重要作用，因此被認為是一種有希望的免疫治療(immune therapy)候選者(candidate)。重組人 CD86 由 230 個氨基酸組成，預計分子量為 26.2 KD。由於糖基化，它在還原條件下在 SDS-PAGE 中遷移為大約 42-66 KD。

Product name	Human CD86/B7-2 protein, His tag (Animal-Free)
Sequence	Amino acid sequence derived from human CD86 (NP_787058) (Met1-Pro247) was expressed with a 6 His tag at the C-terminus.
Protein length	The recombinant human CD86 consists of 230 amino acids and predicts a molecular mass of 26.2 KD. It migrates as an approximately 42-66 KD band in SDS-PAGE under reducing conditions due to glycosylation.
Preparation method	HEK293 Cells
Purity	>95% as determined by SDS-PAGE
Alternative	T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86
Formulation	Lyophilized from sterile PBS, pH 7.4.
Features & Benefits	Endotoxin: < 1.0 EU per µg of the protein as determined by the LAL method.
Molecular weight	26.2 KD
Gene ID	942
Alternative	T-lymphocyte activation antigen CD86; Activation B7-2 antigen; CD86

細胞因子(Cytokine)

細胞因子(Cytokine)作為一種獨特的細胞信號轉導(cell signal transduction)分子，在細胞增殖(cell proliferation)和發育(development)中發揮著重要作用。 Abbkine 為癌症、細胞凋亡、內分泌學、免疫學、神經科學、蛋白酶和乾細胞研究提供細胞因子，包括白細胞介素(interleukin)、趨化因子(chemokine)、集落刺激因子 (colony stimulating factor , CSF)、干擾素(interferon)和轉化生長因子 (transforming growth factor , TGF) 和腫瘤壞死因子 (tumor necrosis factor , TNF) 家族。Abbkine 為您提供細胞因子(Cytokine)，包括白細胞介素、趨化因子、集落刺激因子 (CSF)、干擾素、轉化生長因子 (TGF) 和腫瘤壞死因子 (TNF)，用於癌症、細胞凋亡、內分泌學、免疫學、神經科學、蛋白酶和幹細胞研究。這些細胞因子經每微克蛋白質內毒素，LAL法測定含量小於1.0EU。純度在95%以上，每個細胞因子都配備了1 mL與細胞因子最相容的再溶解緩衝液，因此再溶解後產品性能更穩定。過嚴格驗證，可滿足開發人員對高質量、高生物活性和有競爭力的價格的需求。(Animal-Free) Abbkine細胞培養物（真核細胞）的非動物細胞因子(Animal-free cytokines)是利用非動物(non-animal)原料和表達系統生產的，表達系統中的培養基是無血清、無動物、化學成分透明的。

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PRP1013	Human TNF-α protein
PRP1010	Human bFGF protein
PRP1011	Mouse bFGF protein
PRP1014	Human IFN-γ protein, His Tag
PRP1015	Mouse IFN-γ protein, His Tag
PRP1016	Human GM-CSF protein
PRP1018	Human IL-33 protein
PRP1118	Mouse IL-33 protein
PRP1019	Human IL-1β protein
PRP1119	Mouse IL-1β protein
PRP1020	Human MCP2 protein, SUMO tag
PRP1113	Mouse TNF-α protein
PRP2016	Human GM-CSF protein (Animal-Free)
PRP2117	Mouse IL-4 protein (Animal-Free)
PRP1025	Human IL-2 protein
PRP1126	Mouse LIF protein, C-His tag
PRP1027	Human IL-36α protein
PRP1219	Rat IL-1β protein
PRP1028	Human TRAIL protein
PRP2024	Human CD155/PVR protein, His tag (Animal-Free)
PRP2023	Human CD86/B7-2 protein, His tag (Animal-Free)
PRP2022	Human CD24 protein, hFc tag (Animal-Free)
PRP2021	Human CD274/PD-L1 protein, His tag (Animal-Free)
PRP2112	Mouse IL-6 protein, His tag (Animal-Free)
PRP100005	Human VEGF121 protein
PRP100006	Human VEGF121 protein
PRP100008	Human aFGF protein
PRP100018	Human IL-12β protein, Fc Tag
PRP100022	Human BAFF protein
PRP100033	Human IL-8 protein (aa 23-99)
PRP100039	Human IL-18 protein
PRP100048	Human IL-1α protein
PRP100050	Human IL-1β protein (pro form), His Tag
PRP100051	Human IL-1β protein
PRP100077	Human Noggin protein
PRP100078	Human TNF-β protein
PRP100087	Human FLT3L protein, His Tag
PRP100103	Human IL-15 protein, His Tag
PRP100104	Human IL-15 protein
PRP100108	Human IL-13 protein
PRP100110	Human Thrombopoietin protein, His Tag
PRP100126	Human BMP-2 protein
PRP110126	Mouse BMP-2 protein
PRP120126	Rat BMP-2 protein
PRP100127	Human SCF (aa 1-189) protein, His Tag
PRP100139	Human VEGF-C protein, His Tag
PRP100142	Human GDNF protein
PRP100151	Human Sclerostin protein, His Tag
PRP100153	Human IGF1 protein
PRP100154	Human IGF1 protein
PRP100159	Human EGF protein
PRP100183	Human IFN-β protein
PRP100184	Human IL-35 (IL-12A & IL-27B) protein, Fc Tag
PRP100185	Human CXCL10 protein
PRP100188	Human Latent TGF-β1 protein, His Tag
PRP100190	Human TGF-β1 protein
PRP100221	Human FGF21 protein, His Tag
PRP100227	Human IL-10 protein, His Tag
PRP100228	Human IL-10 protein
PRP100239	Human VEGF165 protein
PRP100240	Human VEGF165 protein
PRP100253	Human IL-31 protein, His Tag
PRP100260	Human RANKL protein, Fc Tag
PRP100262	Human RANKL protein
PRP100263	Human IFN-γ protein
PRP100265	Human M-CSF protein, His Tag
PRP100268	Human M-CSF protein
PRP100272	Human IL-9 protein, His Tag
PRP100273	Human IL-4 protein
PRP100287	Human IL-17 protein, His Tag
PRP100288	Human IL-17 protein, His Tag
PRP100289	Human IL-17 protein
PRP100290	Human IL-17 protein
PRP100298	Human FGF19 protein
PRP100299	Human IL-24 protein, His Tag
PRP100308	Human IL-22 protein
PRP100327	Human IFN-α2 protein
PRP100333	Human IL-5 protein
PRP100371	Mouse IL-6 protein
PRP100372	Mouse IL-21 protein
PRP100386	Mouse VEGF164 protein
PRP100398	Mouse IL-13 protein
PRP100408	Mouse RANKL protein, Fc Tag
PRP100415	Mouse FGF21 protein, His Tag
PRP100449	Mouse Adiponectin protein, His Tag
PRP100489	Mouse GM-CSF protein
PRP100491	Mouse IL-17 protein
PRP100498	Mouse IL-4 protein
PRP100503	Mouse M-CSF protein
PRP100618	Rat TGF-β1 protein
PRP110618	Mouse TGF-β1 protein
PRP100705	Human IL-12 (IL-12A & IL-12B) protein, His Tag
PRP100730	Human Leptin protein
PRP1001	Human FGF1/FGF acidic protein
PRP1017	Mouse TGF-β1 protein, His tag (Animal-Free)
PRP1210	Rat bFGF protein
PRP2025	Human CD20 protein, His tag (Animal-Free)
PRP2026	Human CD22/SIGLEC-2 protein, His tag (Animal-Free)
PRP2027	Human CD38 protein, His tag (Animal-Free)
PRP2028	Human CD80/B7-1 protein, His tag (Animal-Free)
PRP1002	Human CNTF protein
PRP1029	Human IL-36γ protein
PRP1213	Rat TNF-α protein
PRP2029	Human CD3E protein, Fc tag (Animal-Free)
PRP2030	Human CD19 protein, Fc tag (Animal-Free)
PRP2031	Human CD28 protein, Fc tag (Animal-Free)
PRP2032	Human CD33/Siglec-3 protein, His tag (Animal-Free)
PRP2033	Human CD7/GP40 protein, His tag (Animal-Free)
PRP2034	Human CD30/TNFRSF8 protein, His tag (Animal-Free)
PRP2035	Human CD40/TNFRSF5 protein, His tag (Animal-Free)
PRP2036	Human CD73/NT5E protein, His tag (Animal-Free)
PRP2037	Human CD84/SLAMF5 protein, His tag (Animal-Free)
PRP2038	Human CD226/DNAM-1 protein, His tag (Animal-Free)
PRP2015	Human IL-3 protein, His tag (Animal-Free)
PRP2114	Mouse IL-13 protein, His tag (Animal-Free)
PRP1021	Human IL-1α/IL1A protein
PRP2039	Recombinant SARS-CoV-2 Spike RBD Protein, His tag (Animal-Free)
PRP1114	Mouse RANKL protein
PRP1211	Rat EGF protein
PRP1022	Human IL-8 protein
PRP1023	Human IL-18 protein
PRP1214	Rat IFN-γ protein
PRP1024	Human TGF-α protein
PRP2041	Human Transferrin protein
PRP2017	Human IL-4 protein
PRP2116	Mouse GM-CSF protein
PRP1030	Human FGF21 protein
PRP1031	Human sRANKL protein