Human GM-CSF protein (Animal-Free)重組蛋白 |貨號PRP2016

產品介紹:粒細胞-巨噬細胞集落刺激因子 (Granulocyte-macrophage colony-stimulating factor , GM-CSF) 是一種細胞因子(cytokine)，可刺激來自各種譜系的造血前體細胞(hematopoietic precursor cells)的生長(growth)和分化(differentiation)，包括粒細胞(granulocytes)、巨噬細胞(macrophages)、嗜酸性粒細胞(, eosinophils)和紅細胞(erythrocytes)。 GM-CSF 用於治療骨髓移植(bone marrow transplant)後的骨髓重建(reconstitution)、骨髓移植植入(bone marrow transplant engraftment)失敗或延遲(delay)、自體外周血祖細胞(autologous peripheral blood progenitor cells)的動員和移植後，以及患有急性髓性白血病 (acute myelogenous leukemia, AML) 的老年人的誘導化療(induction chemotherapy)後。

Product name	Human GM-CSF protein (Animal-Free)
Sequence	Amino acid sequence derived from human GM-CSF (NP_000749.2) (Met1-Glu144) was expressed with a 6His tag at the C-terminus.
Protein length	The recombinant human GM-CSF consists of 127 amino acids and predicts a molecular mass of 14.5 kDa. It migrates as an approximately 23.8 kDa band in SDS-PAGE under reducing conditions due to glycosylation.
Preparation method	HEK293 Cells
Purity	>98 % as determined by SDS-PAGE
Alternative	GM-CSF; GMCSF; Granulocyte-macrophage colony-stimulating factor; CSF2
Formulation	Lyophilized from sterile PBS, pH 7.4.
Features & Benefits	Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method.
Molecular weight	14.5-23.8 kDa
Usage notes	Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized Human GM-CSF protein using the buffer we provided not less than 100 µg/ml, which can then be further diluted to other aqueous solutions.
Storage instructions	Lyophilized Human GM-CSF protein (Animal-Free)should be stored desiccated below -20°C. Upon reconstitution, the protein should be stored at 4°C between 2-7 days and for future use below -20°C. For long term storage it is recommended to add a carrier protein (0.14% HSA or BSA). Please prevent freeze-thaw cycles.
Shipping	The product is shipped at ambient temperature.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.