氯丙嗪 (Chlorpromazine) | A dopamine receptor antagonist CAS #69-09-0貨號B1992

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氯丙嗪 (Chlorpromazine) | A dopamine receptor antagonist CAS #69-09-0貨號B1992
A dopamine receptor antagonist
產品介紹: 氯丙嗪 (Chlorpromazine) 是一種多巴胺受體拮抗劑(dopamine receptor antagonist)。減少神經遞質(neurotransmitter binding)的結合。抑制小鼠腦細胞溶膠中一氧化氮(nitric oxide synthesis)的合成。也可作為nAChR,組胺(histamine)和5-HT受體的拮抗劑。對多種腫瘤細胞系顯示出生長抑制作用。表現出抗精神病活性(antipsychotic activity)。
| Alternate Name | 2-Chloro-N,N-dimethyl-10H-phenothiazine-10-propanamine, monohydrochloride; CPZ; Thorazine; Promacid |
| Appearance | White to off-white solid |
| CAS # | 69-09-0 |
| Molecular Formula | C₁₇H₁₉ClN₂S • HCl |
| Molecular Weight | 355.32 |
| Purity | ≥98% |
| Solubility | DMSO (~ 30 mg/ml) |
| SMILES | N(C)CCCN1C2=CC=CC=C2SC3=C1C=C(C=C3)Cl.Cl |
| InChi | InChI=1S/C17H19ClN2S.ClH/c1-19(2)10-5-11-20-14-6-3-4-7-16(14)21-17-9-8-13(18)12-15(17)20;/h3-4,6-9,12H,5,10-11H2,1-2H3;1H |
| InChi Key | FBSMERQALIEGJT-UHFFFAOYSA-N |
| PubChem CID | 6240 |
| MDL Number | MFCD00012654 |
| Handling | Protect from air and moisture |
| Storage Conditions | RT |
| Shipping Conditions | RT |
